Unlock instant, AI-driven research and patent intelligence for your innovation.

Application of atemisia gmelinii extract in preparing drugs for preventing liver injuries

A liver injury and drug technology, applied in the field of extracts of Artemisia japonica, can solve the problem of no particularly good method, and achieve the effect of significant curative effect and wide range of sources.

Active Publication Date: 2012-03-21
朴光春
View PDF2 Cites 4 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] There is no particularly good way to treat and prevent liver damage in clinical practice

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Application of atemisia gmelinii extract in preparing drugs for preventing liver injuries
  • Application of atemisia gmelinii extract in preparing drugs for preventing liver injuries
  • Application of atemisia gmelinii extract in preparing drugs for preventing liver injuries

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0013] 1. Separation of monomeric compounds

[0014] Take 1500g of Artemisia persicae, soak in water for 3 hours, heat for 2 hours, filter to obtain filtrate I, add water to the residue and heat for 1 hour to obtain filtrate II, combine filtrates I and II to obtain Artemisia persicae water extract. Add the water extract of Artemisia tennensis to the pretreated macroporous adsorption resin column, elute with distilled water, 50% ethanol, and 95% ethanol in turn, collect the 50% ethanol eluate, concentrate, freeze-dry to dryness, and extract the The 50% ethanol eluate of Artemisia tennensis was dissolved in water, extracted with dichloromethane and ethyl acetate in sequence to obtain dichloromethane extract, ethyl acetate extract and the remaining water-soluble part. An appropriate amount of the remaining water-soluble part was loaded on a pretreated reversed-phase silica gel column, and gradient elution was carried out in a methanol-water system. Observation and judgment base...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a 2-hydroxyl-6-methoxy acetophenone-4-O-Beta-D-glucoside which is obtained by separating atemisia gmelinii and an application of acetophenone-4-O-Beta-D-glucoside and 6-methoxy-quercitin patuletin-7-O-Beta-D-glucoside in preparing drugs for preventing liver injuries. The active components of the drug of the invention are obtained by extracting and separating the atemisia gmelinii, the source of the active components is wide, and the liver injury curative effects are obvious.

Description

technical field [0001] The invention relates to the extract of Artemisia argyi, in particular to an anti-liver damage monomer compound isolated from Artemisia argyi. Background technique [0002] Liver injury is a pathological state with outstanding characteristics shared by many liver diseases, which seriously threatens human health. Various harmful factors such as drugs, viruses, alcohol, organisms, etc. may cause liver function to be damaged to varying degrees, thereby reducing liver detoxification, excretion function, reserve and regeneration capacity, reducing liver blood flow, and aggravating metabolic load, resulting in endogenous diseases. Environmental disturbance, liver cell necrosis and apoptosis, and then cause liver damage. Liver damage caused by various harmful factors mainly includes drug-induced liver damage, viral liver damage, alcohol-induced liver damage, and immune liver damage. Billions of people around the world have suffered or are suffering from live...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7048A61K31/7034A61P1/16
Inventor 朴光春元海丹
Owner 朴光春