Programmable young animal frightening stimulus stress experiment system

An experimental system and small animal technology, applied in the field of rodent stress experimental system, can solve the problems of poor flexibility, poor consistency in the study of mouse stress reflex behavior, unfavorable independent design of experimental procedures, etc., to facilitate experimental observation and ensure normal survival The effect of experimental environment, great flexibility and practicality

Inactive Publication Date: 2012-03-28
TIANJIN UNIV OF SPORT
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] 1. The non-mechatronic system has a complex structure, a large volume, and takes up a lot of space;
[0006] 2. The use of fixed program software has poor flexibility and is not conducive to independent design of experimental programs;
[0007] 3. The types of small animal stress reflex stimulation signals and their programming combination functions can not meet the experimental needs well. The stress stimulation experiment box has no odor stimulation signal channel, so it is impossible to carry out olfactory stress experiments.
[0008] 4. There is an electric shock blind area on the ground of the electric stimulation grid in the stress test cage, so when the rat stands on the grid with the same potential, it may avoid the electric shock on the sole of the foot;
[0010] 6. The joint test operation of the existing stress and panic test system is not only cumbersome, but also difficult to ensure the same experimental environment and the same various stress test conditions required by the stress test of the same batch of experimental mice, so the same batch of rat stress tests are produced. Poor Consistency in Research on Reflex Behavior

Method used

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  • Programmable young animal frightening stimulus stress experiment system
  • Programmable young animal frightening stimulus stress experiment system
  • Programmable young animal frightening stimulus stress experiment system

Examples

Experimental program
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Effect test

Embodiment 2

[0030] Programmable small animal panic stimulation stress experiment system, on the basis of embodiment 1, programmable small animal panic stimulation stress experiment system, programmable panic stimulation time controller is a module for controlling panic stimulation signals, installed in the controller on the front panel.

Embodiment 3

[0032] Programmable small animal panic stimulation stress experiment system, on the basis of Embodiment 1 or 2, the stress experiment equipment subsystem is a soundproof box that can eliminate external interference. The box is divided into three layers from bottom to top, and the lower part is the shaft. The blower layer 5 has a removable cleaning tray 4 in the middle, and six independent squirrel cage compartments 2 isolated from each other on the top.

Embodiment 4

[0034] Programmable small animal panic stimulation stress experiment system, on the basis of embodiment 3, the ground of each independent restraint mouse cage cabin is made of stainless steel grid electric shock floor 3, and the door on the front face is provided with food tank, drinking water pipe 7 and transparent Observation window, the rear end face is provided with blowing / smell air inlet (not shown in the figure), and the two sides are pluggable stainless steel plates.

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Abstract

The invention relates to a programmable young animal frightening stimulus stress experiment system. The system comprises a stress experiment equipment subsystem and an electric appliance control subsystem, and is characterized in that the stress experiment equipment subsystem and the electric appliance control subsystem are installed in the same sealed sound-insulation box; the electric appliance control subsystem is an electromechanical integrated structure composed of an electronic stimulus control part and a programmable frightening stimulus signal time controller; and the electric appliance control subsystem is installed at top part of an experiment equipment isolation box. The system has the beneficial effects that: the defects in the prior art are overcome; by structure innovation, electric striking without blind zones is achieved as well as wind stimulus and odor stimulus are increased; the programmable experiment system can conveniently provide multiple quantized young animal stress reflection stimulus signals, and research the mouse stress reflex behavior under the condition that multiple mice undergo various frightening stimuli in the same environment; and the stimulus integration scheme can be freely defined according to the preset corresponding stimulus stress environment.

Description

technical field [0001] The invention relates to a mouse stress experiment system. Background technique [0002] The reflex process of small animals in the environment of panic stimulation should be the stress effect, which is the response of multicellular higher animals to various stimuli through the nervous system. The startle stress effect experiment enables the experimentation of small rodent reflexes with the help of quantified "stimulus events" that occur in the small animal's environment. The startle stimulation experiment can be composed of one "stimulus event", and several independent "stimulus events" can form a complex startle stimulation experiment system at the same time, which can experiment, observe and measure the reflex state of small animals to multivariate stimuli. The quantification experiment of the reflex behavior stimulus signal of small animals in the frightened environment is an effective method to study the refinement of stress characteristics. [...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01K29/00
Inventor 文立金亚虹张赛
Owner TIANJIN UNIV OF SPORT
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