Method for preparing cardiac medicament eluting stent with deer blood

Abstract

The invention discloses a method for preparing a cardiac medicament eluting stent with deer blood. The method comprises the following steps of: pouring deer blood into a cardiac medicament eluting stent mold; and standing and drying to obtain the product. The cardiac medicament eluting stent prepared by using the method can be degraded completely, and can be used for suppressing the hyperplasia and translation of smooth muscle cells, promoting the growth of endothelial cells and accelerating endothelialization.

Description

technical field [0001] The invention relates to a method for preparing a heart drug stent by using deer blood. Background technique [0002] In recent years, percutaneous coronary intervention (PCI) has surpassed percutaneous transluminal coronary angioplasty (GABC) and has become the most commonly used procedure for the treatment of coronary artery disease. Since Gruentzig completed the world's first percutaneous transluminal coronary angioplasty (PTCA) in Zurich, Switzerland in 1977, it ushered in a new era of interventional heart disease treatment. Intracoronary bare metal stent (BMS, 1985) and drug-eluting stent (DES, 2003) placed two historic leaps. However, although the probability of in-stent restenosis after using drug-eluting stents is significantly lower than that of bare metal stents, the problem of restenosis has not been fundamentally resolved. Delayed, stent thrombosis. In view of this, a new type of biodegradable coated stent has emerged as the times requir...

AI Technical Summary

Problems solved by technology

The drugs currently on the market for coated degradable stents are still rapamycin or paclitaxel, both of which can inhibit the proliferation and migration of vascular smooth muscle cells, so drug-coated stents can reduce in-stent restenosis , but at the same time, these two drugs also inhibit the growth of endothelial cells, resulting in delayed endothelialization, which can easily lead to the formation of late thrombus in the stent