Method for increasing endogenous plasmalogen levels in mammals

A plasmalogen, mammalian technology, used in the field of alkylglycerols and alkoxyglycerols, capable of addressing diseases and disorders, adverse animal health, reducing
CN102413822AInactive Publication Date: 2012-04-11NESTEC SA
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
NESTEC SA
Publication Date
2012-04-11
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention relates generally to compounds such as alkylglycerol and alkoxyglycerol for use in increasing the endogenous level of plasmalogens in a mammal. In particular, these compounds are used for increasing the endogenous plasmalogen level to a level greater than the level in healthy mammals. According to the present invention such compounds are also for use in the prevention or treatment of diseases caused or affected by a decreased endogenous level of plasmalogens. A method for the manufacture of a dietary precursor for the use of the present invention is also part of the present disclosure.
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Description

field of invention

[0001] In general, the present invention relates to compounds, such as alkylglycerols and alkoxyglycerols, for increasing the level of endogenous plasmalogens in mammals. In particular these compounds are useful for increasing endogenous plasmalogen levels above levels in healthy mammals. According to the invention, said compounds are also useful in the prevention or treatment of diseases caused or affected by reduced endogenous plasmalogen levels. Methods of preparing dietary precursors for use in the present invention are also part of this disclosure. Background technique

[0002] Plasmalogens, their structures and applications are well known to those skilled in the art.

[0003]

[0004] Plasmalogens are glyceryl ether phospholipids in which the glycerol moiety is bonded to a 1-alkenyl ether group or a 1-alkyl ether group. Three major classes of plasmalogens have been identified and referred to as choline, ethanolamine, and serine plasmalogens. T...

Claims

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