Electrostatically charged multi-acting nasal application, product and method

A technology for preventing static electricity and nasal passages, which is used in medical preparations, pharmaceutical formulations, and antibacterial drugs that are not active ingredients.

Inactive Publication Date: 2012-05-02
TRUTEK CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

While this behavior may provide suitable protection against passively inhaled particles, they suffer from the fact that they cannot fully deal with particles that themselves have built-in ways of overcoming electrostatic forces, such as microorganisms active in air streams

Method used

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  • Electrostatically charged multi-acting nasal application, product and method
  • Electrostatically charged multi-acting nasal application, product and method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0116]Embodiment 1 composition (S1), embodiment 3 composition (S3) and contrast (C1)

[0117] (Control: α2,6-sialyllactosamine polymer (6’-SLN) 20 mg / mL)

[0118] (c) Test method

[0119] (1) Spread MDCK cells on a 96-well plate and culture overnight to form a cell layer at the bottom of the well.

[0120] (2) The above-mentioned test samples (S1, S3, C1) were dissolved in a phosphate-buffered saline (PBS) solution at a concentration of 1 mg / mL.

[0121] (3) Two kinds of virus solutions of swine influenza virus (A / Osaka) and influenza virus (A / New Caledonia) were prepared as 4.0×10 5 CIU / mL, 50 μL of each was mixed with the test sample, and reacted at 25°C for 0.5 hours.

[0122] (4) Remove the cell culture medium from each well by aspiration, add 50 μL of each test sample and virus reaction mixture onto the cell layer of 2 wells, and incubate in 5% CO 2 Adsorption to it was allowed for 0.5 hours at 37°C in an incubator.

[0123] (5) DMEM medium (150 μL) was added to ea...

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Abstract

Provided are a product to reduce and a method of reducing the risk of inhalation of harmful substances by applying a formulation composition to a substrate or the skin in close proximity of one or more nostrils. This formulation, when applied creates an electrostatic field having a charge. The electrostatic field attracts airborne particulates of opposite charge to the substrate that are in close proximity to the substrate close to the skin and a biocidic agent renders microorganisms coming in contact the substrate or skin less harmful.

Description

[0001] Cross References to Related Applications [0002] a) This application claims the benefit and priority of my pending US non-provisional patent application Serial No. 12 / 467,271 filed May 16, 2009, which is hereby incorporated by reference in its entirety. [0003] b) This application claims the benefit and priority of my pending International Application No. PCT / US09 / 44755, filed May 20, 2009, which is hereby incorporated by reference in its entirety. field of invention [0004] The present invention relates to the field of protective compositions against attack by various irritants and noxious substances and attack by various microorganisms which typically enter the body through the respiratory and / or nasal mucosa. The present invention also relates to antiviral, antibacterial and antimicrobial products including the use of products hitherto developed to limit the flow of airborne pollutants into the nasal passage by creating an electrostatic field adjacent to the area ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/72A61K47/30A61P17/00
CPCA61K47/14A61K9/0009A61K9/0043A61K47/186A61K47/10A61P11/02A61P17/00A61P31/02A61P31/04A61P31/12A61P43/00
Inventor A.L.瓦希
Owner TRUTEK CORP
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