Shenkang tablet for treating chronic renal failure and preparation method of Shenkang tablet

A technology for Shenkang tablets and chronic renal failure, which is applied to medical preparations containing active ingredients, pill delivery, and pharmaceutical formulas, and can solve problems such as no ratio relationship, affecting drug efficacy, and high usage of astragalus

Active Publication Date: 2012-05-30
XIAN SHIJISHENGKANG PHARMA IND
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] The original patent 200410039418.X discloses a kind of Shenkang suppository and its preparation method. Its prescription protects the scope of use of traditional Chinese medicine, and there is no specific ratio relationship. Although the case of the prescription is also disclosed i

Method used

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  • Shenkang tablet for treating chronic renal failure and preparation method of Shenkang tablet
  • Shenkang tablet for treating chronic renal failure and preparation method of Shenkang tablet
  • Shenkang tablet for treating chronic renal failure and preparation method of Shenkang tablet

Examples

Experimental program
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Effect test

Embodiment 1

[0104] Shenkang tablet is made from the raw materials in the following proportions: rhubarb 1500g, salvia miltiorrhiza 1500g, astragalus membranaceus 4500g, safflower 1500g.

[0105] The preparation method of Shenkang tablet is: after extracting the raw materials rhubarb and salvia miltiorrhiza according to the proportion of the above formula, first alcohol precipitation, detanning, second alcohol precipitation, water precipitation, third alcohol precipitation, and second water precipitation ; then extract the astragalus and safflower according to the proportion of the above formula, alcohol precipitation, water precipitation, alcohol precipitation, water precipitation again, ultrafiltration and concentration to make tablets.

Embodiment 2

[0107] Shenkang tablet of the present invention, its preparation method is: take rhubarb g, salvia miltiorrhiza, the amount of water added for the first time is 7-12 times of the original medicinal materials, after soaking for 30 minutes, boil for 30 minutes, filter, and the amount of water added for the second time is the original amount. 7-12 times the amount of medicinal materials, boil for 30 minutes, filter, add water for the third time to 7-12 times the original medicinal materials, boil for 30 minutes, filter, combine three water extracts, concentrate to a relative density of 1.18 at 60°C 1.25, add 95% ethanol until the alcohol content of the liquid is 70%, let it stand for 38-60h, take the supernatant and filter until clear, recover the ethanol until the relative density is 1.18-1.25 at 60°C, add 5% gelatin solution, In addition to tanning, add 95% ethanol until the alcohol content is 75%, let it stand for 38-60 hours, take the supernatant and filter it to clarify, reco...

Embodiment 3

[0109] The preparation method of the Shenkang tablet of the present invention is as follows: take rhubarb and salvia miltiorrhiza, add water for the first time to 10 times the amount of the original medicinal materials, soak for 30 minutes, boil for 30 minutes, filter, and add water for the second time to be 8 times the original medicinal materials amount, boiled for 30 minutes, filtered, the third time added water was 7 times the amount of the original medicinal material, boiled for 30 minutes, filtered, combined three water extracts, concentrated to a relative density of 1.20-1.22, added 95% ethanol, until the liquid contained The alcohol content is 70%, let it stand for 48-60h, take the supernatant and filter until clear, recover the ethanol until the relative density is 1.20-1.22 at 60°C, add 5% gelatin solution, remove tanning, add 95% ethanol, until it contains alcohol The dosage is 75%, stand still for 48-60h, take the supernatant, filter and clarify, recover the ethanol...

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Abstract

The invention relates to a Shenkang tablet for treating chronic renal failure and a preparation method of the Shenkang tablet. The Shenkang tablet for treating chronic renal failure is prepared from the following bulk pharmaceutical chemicals: 1500g of rheum officinale, 1500g of roots of red-rooted salvia, 4500g of Astragalus mongholicus and 1500g of red flower. The preparation method comprises the following steps of: after the bulk pharmaceutical chemicals of the rheum officinale and the roots of the red-rooted salvia are extracted in the ratio in the formula, carrying out primary ethanol precipitation, removing tan, carrying out secondary ethanol precipitation and water precipitation, carrying out third ethanol precipitation, and carrying out secondary water precipitation; then, extracting the red flower and the Astragalus mongholicus in the ratio in the formula, carrying out primary ethanol precipitation and water precipitation, carrying out secondary ethanol precipitation and water precipitation, and preparing into an extract after the mixture is condensed; and drying to obtain the tablet. The Shenkang tablet for treating chronic renal failure has the advantages of precision in regulating the original ratio, small side effect, definite curative effect and convenience in use, carrying and storage.

Description

technical field [0001] The invention belongs to traditional Chinese medicine tablets and a preparation method thereof, in particular to a Shenkang tablet for treating chronic renal failure and a preparation method thereof. Background technique [0002] The original patent 200410039418.X discloses a kind of Shenkang suppository and its preparation method. Its prescription protects the scope of use of traditional Chinese medicine, and there is no specific ratio relationship. Although the case of the prescription is also disclosed in the patent document embodiment, but Astragalus is used in a high amount, because astragalus and rhubarb have a precipitation reaction, and astragalus and salvia miltiorrhiza may also react. If the amount of astragalus used in the preparation is small, the efficacy of the medicine will be affected. The proportioning relationship of traditional Chinese medicine directly affects the curative effect of the preparation, so the accuracy of the prescripti...

Claims

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Application Information

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IPC IPC(8): A61K36/708A61K9/20A61P13/12
Inventor 曹凤君吕延英詹芳赵兴王光建王俊平
Owner XIAN SHIJISHENGKANG PHARMA IND
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