Shenkang dripping pill for treating chronic renal failure and preparation method thereof

A technology for chronic renal failure and Kang dripping pills, applied in the directions of medical preparations containing active ingredients, pill delivery, pharmaceutical formulations, etc., can solve the problems of high proportion of astragalus, accuracy, small side effects, and no proportioning relationship.

Active Publication Date: 2012-05-30
XIAN SHIJISHENGKANG PHARMA IND
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] The original patent 200410039418.X discloses a Shenkang suppository and its preparation method. This patent protects the composition and preparation method. The case of the prescription is also disclosed in the example, but the proportion of Astragalus membranaceus is high. Because Astragalus membranaceus and rhubarb have a precipitation reaction, Astragalus membranaceus and Salvia miltiorrhiza also have a reaction, and the small amount of Astragalus membranaceus in the compatibility of the preparation also affects the efficacy of the medicine. The proportion of traditional Chinese medicine directly affects Efficacy, precision and minimal side effects of formulation are critical

Method used

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  • Shenkang dripping pill for treating chronic renal failure and preparation method thereof
  • Shenkang dripping pill for treating chronic renal failure and preparation method thereof
  • Shenkang dripping pill for treating chronic renal failure and preparation method thereof

Examples

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Effect test

Embodiment 1

[0092] Dropping pills are made from the raw materials of the following proportions: rhubarb 1500g, salvia miltiorrhiza 1500g, astragalus 4500g, safflower 1500g. When producing Shenkang dripping pills, after extracting the raw materials rhubarb and salvia miltiorrhiza according to the above formula ratio, first alcohol precipitation, detanning, second alcohol precipitation, water precipitation, third alcohol precipitation, and second water precipitation; Astragalus and safflower are extracted according to the proportion of the above formula, alcohol-precipitated again, water-precipitated, alcohol-precipitated, water-precipitated again, ultra-filtered, concentrated to make a concentrated solution, and prepared by formulating→molding→quality inspection→packaging become.

Embodiment 2

[0094] Shenkang dripping pills of the present invention, its preparation method is: after selecting 1500g of rhubarb, 1500g of salvia miltiorrhiza, 4500g of astragalus, and 1500g of safflower medicinal materials, cleaning, soaking, cutting, drying; weighing 1500g of rhubarb and 1500g of salvia miltiorrhiza , the amount of water added for the first time is 7-12 times the amount of the original medicinal material, soaked for 30 minutes, boiled for 30 minutes, filtered, the amount of water added for the second time is 7-12 times the amount of the original medicinal material, boiled for 30 minutes, filtered, and the third time The amount of water added is 7-12 times the amount of the original medicinal material, boiled for 30 minutes, filtered, combined three water extracts, concentrated to a relative density of 1.18-1.25 at 60°C, and 95% ethanol was added until the alcohol content of the liquid was 70%. Stand still for 38-60 hours, take the supernatant and filter until clear, reco...

Embodiment 3

[0096] Shenkang dripping pills of the present invention, its preparation method is: after selecting 1500g of rhubarb, 1500g of salvia miltiorrhiza, 4500g of astragalus, and 1500g of safflower medicinal materials, cleaning, soaking, cutting, drying; weighing 1500g of rhubarb and 1500g of salvia miltiorrhiza The amount of water added for the first time is 10 times the amount of the original medicinal material, soaked for 30 minutes, boiled for 30 minutes, filtered, the amount of water added for the second time is 8 times the amount of the original medicinal material, boiled for 30 minutes, filtered, and the amount of water added for the third time is the original 7 times the amount of the medicinal material, boiled for 30 minutes, filtered, combined three water extracts, concentrated to a relative density of 1.20-1.22 at 60°C, added 95% ethanol, until the alcohol content of the medicinal solution was 70%, and stood for 48-60 hours. Take the supernatant and filter until clear, rec...

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Abstract

The invention relates to a Shenkang dripping pill for treating chronic renal failure and a preparation method of the dripping pill. The dripping pill is prepared from Radix Et Rhizoma Rhei 1500g, Radix Salviae Miltiorrhizae 1500g, Radix Astragali 4500g and Flos Carthami 1500g. The preparation method comprises the following steps of: extracting Radix Et Rhizoma Rhei and Salviae Miltiorrhizae according to the above formula amounts, conducting alcohol precipitation for the first time, removing tannins, performing alcohol precipitation for the second time, precipitating with water, performing alcohol precipitation for the third time, and precipitating with water again; and extracting Radix Astragali and Flos Carthami according to the above formula amounts, performing alcohol precipitation for the first time, precipitating with water, conducting alcohol precipitation for the second time, precipitating with water again, concentrating to obtain a concentrated solution, and making into the dripping pill. The Shenkang dripping pill of the invention is obtained through precise adjustment on the basis of an original ratio; and has low side effects, rapid onset of drug actions, definite therapeutic effects and convenience for use.

Description

technical field [0001] The invention belongs to traditional Chinese medicine dropping pills and a preparation method thereof, in particular to Shenkang dropping pills for treating chronic renal failure and a preparation method thereof. Background technique [0002] The original patent 200410039418.X discloses a Shenkang suppository and its preparation method. This patent protects the composition and preparation method. The case of the prescription is also disclosed in the example, but the proportion of Astragalus membranaceus is high. Because Astragalus membranaceus and rhubarb have a precipitation reaction, Astragalus membranaceus and Salvia miltiorrhiza also have a reaction, and the small amount of Astragalus membranaceus in the compatibility of the preparation will also affect the efficacy of the medicine. The proportion of traditional Chinese medicine directly affects Efficacy, precision and minimal side effects of the formulation are crucial. Contents of the invention...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/708A61K9/20A61P13/12
Inventor 曹凤君吕延英詹芳赵兴王光建王俊平
Owner XIAN SHIJISHENGKANG PHARMA IND
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