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Quick micro-mixing device for high-viscosity solution

A micro-mixing, high-viscosity technology, used in mixers, mixing methods, dissolution, etc., can solve the problems of long mixing time and complex structure, and achieve the effect of reducing pollution and wide application prospects.

Active Publication Date: 2012-06-20
HUAZHONG UNIV OF SCI & TECH
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  • Abstract
  • Description
  • Claims
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Problems solved by technology

[0006] The purpose of the present invention is to overcome the shortcomings of the existing high-viscosity solution micro-mixing device with complex structure and long mixing time, and provide a micro-mixing device with simple structure, simple processing and short mixing time

Method used

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  • Quick micro-mixing device for high-viscosity solution
  • Quick micro-mixing device for high-viscosity solution
  • Quick micro-mixing device for high-viscosity solution

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Embodiment Construction

[0018] The present invention will be described in detail below in conjunction with accompanying drawings and examples.

[0019] The rapid micro-mixing device includes a PDMS thin layer, and three connected channels are processed on the PDMS thin layer, wherein two solution inlet channels a and b are symmetrical about the third solution outlet channel c, and the sequential processing in the solution outlet channel has multiple an ω-shaped microstructure. The three-channel connection can be Y-shaped, T-shaped or arrow-shaped, and the two openings of the ω-shaped microstructure face the intersection of the three channels. As an optimization, the ω-shaped microstructures are arranged in the channel in such a way that the size difference between the left and right openings is alternately positive and negative. Compared with the method of simply repeatedly arranging the ω-shaped microstructures in the channel, this method can more effectively cause the disturbance of the solution, ...

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Abstract

The invention discloses a quick micro-mixing device for high-viscosity solution. The device comprises a PDMS (Polydimethylsiloxane) thin layer, and is characterized in that: three communicated passages are processed on the PDMS thin layer, wherein two solution inlet passages are symmetric about a third solution outlet passage; a plurality of w-shaped microstructures are sequentially processed in the solution outlet passage; and two openings of the w-shaped microstructures face an intersection of the three passages. The device has a simple structure and a simple processing process and can finish full mixing of the high-viscosity solution in 500 microseconds.

Description

technical field [0001] The invention relates to a rapid micro-mixing device for high-viscosity solutions, which can realize microsecond-level mixing of high-viscosity sample solutions, and is widely used in the field of kinetic research of biological macromolecules such as proteins or DNA in crowded environments. Background technique [0002] Microfluidic lab-on-a-chip is an important scientific technology in this century, which is characterized by shrinking a biological or chemical laboratory to a sheet of only a few square centimeters, which is realized through structures such as microchannels, microvalves and micropumps. The integration of a series of operating units such as sample injection, pretreatment, mixing, reaction, and detection. This micro-platform with high-density integration of multi-functional units can greatly shorten the sample processing time and significantly improve the detection resolution. At present, microfluidic chips have been used in many industri...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01F13/00B01F3/10B01F23/47
Inventor 刘笔锋李颖徐友志冯晓均
Owner HUAZHONG UNIV OF SCI & TECH
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