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Traditional Chinese medicine compound composition

A composition and technology of traditional Chinese medicine, applied in the field of compound Chinese medicine composition, can solve problems such as unsatisfactory dosage form, unacceptable to patients, high price, etc.

Inactive Publication Date: 2012-07-04
DISHA PHARMA GRP +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Investigations on the use of clinical antitussives show that among the existing antitussives, some prescriptions are biased against cold and heat, and the clinical applicability is poor; some dosage forms are not ideal, and it is inconvenient for children to take them; ; Imported drugs have certain side effects, and the price is very expensive, which is difficult for ordinary patients to accept

Method used

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  • Traditional Chinese medicine compound composition
  • Traditional Chinese medicine compound composition
  • Traditional Chinese medicine compound composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Prescription: Baibu 332g, Aster (honey-roasted) 250g, Peucedanum 250g, Campanulaceae 250g, Silkworm (stir-fried with bran) 187g, Cicada slough 125g, Ephedra 125g, Bitter almond (stir-fried) 187g, Reed root 250g, Black plum 125g, Roasted licorice 125g.

[0032] Preparation steps:

[0033] The first step is to add 70% ethanol to reflux for three times, add 8 times the amount of 70% ethanol for the first time, and reflux for 2 hours. Add 5 times the amount of 70% ethanol for the second time, reflux for 1 hour, add 5 times the amount of 70% ethanol for the third time, and reflux for 0.5 hours. The extracts were combined, filtered, and the filtrate recovered ethanol under reduced pressure and concentrated to a thick paste with a relative density of 1.15-1.25 (50°C).

[0034] The second step is aster (honey-roasted), platycodon, silkworm (bran-fried), cicada slough, reed root, black plum, and roasted licorice. Add 10 times the amount of water, decoct for 1 hour, combine th...

Embodiment 2

[0039] Prescription: Baibu 380g, Aster (honey-roasted) 238g, Peucedanum 238g, Campanulaceae 242g, Silkworm (stir-fried with bran) 178g, Cicada slough 128g, Ephedra 128g, Bitter almond (stir-fried) 178g, Reed root 238g, Black plum 128g, Roasted licorice 128g.

[0040] The composition was prepared according to the preparation method of Example 1, except that the granulation method in the third step of this example was spray granulation. The material temperature is controlled at 40-66°C.

Embodiment 3

[0042]Prescription: Baibu 200g, Aster (honey-roasted) 300g, Peucedanum 300g, Campanulaceae 300g, Silkworm (stir-fried with bran) 200g, Cicada slough 100g, Ephedra 100g, Bitter almond (stir-fried) 250g, Reed root 300g, Black plum 100g, Roasted licorice 100g.

[0043] The composition was prepared according to the preparation method of Example 1, except that the granulation method in the third step of this example was dry granulation under reduced pressure. Vacuum degree≤0.086Mpa, temperature 55~70℃.

[0044] According to the basic requirements of pharmacodynamic research in the "Guidelines for the Research of New Drugs of Traditional Chinese Medicine", refer to "Chinese Medicines for the Treatment of Exogenous Heat Syndrome", "Traditional Chinese Medicines for the Treatment of Chronic Bronchitis" and "Antitussives" and According to the relevant content stipulated in the "expectorant", the following researches have been carried out on the efficacy of the composition of the prese...

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Abstract

The invention relates to a traditional Chinese medicine compound composition with the functions of relieving cough to reduce sputum, diffusing the lung to promote qi and dispersing superficies to scatter evil, and a preparation method of the traditional Chinese medicine compound composition. The composition consists of 11 kinds of traditional Chinese medicine: radix stemonae, radix asteris, peucedanum root, platycodon grandiflorum, stiff silkworm, cicada slough, ephedra, semen armeniacae amarae, rhizoma phragmitis, smoked plum and honey-fried licorice root.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition which has the functions of relieving cough and reducing phlegm, promoting lung and strengthening qi, and relieving external evils and a preparation method thereof. The composition is composed of 11 traditional Chinese medicines such as babu, aster, peucedanum, bellflower, silkworm, cicada slough, ephedra, bitter almond, reed rhizome, ebony plum and roasted licorice. Background technique [0002] Cough is a disease caused by pathogenic factors invading the lung system, causing the lung qi to go up against the sound or spit up saliva. From the perspective of pathogenesis, Chinese medicine divides cough into two types: "internal injury" and "exogenous pathogenesis". The onset of exogenous cough is more acute, and there are obvious exogenous triggers. The main manifestations are severe cough, thick sputum, itchy throat and cough, nasal congestion and headache, aversion to cold and fever, ...

Claims

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Application Information

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IPC IPC(8): A61K36/904A61P11/10A61P11/14A61K35/64
Inventor 岳丽萍谢爱芳
Owner DISHA PHARMA GRP
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