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Chinese medicinal preparation for treating mild cognitive impairment

A technology for mild cognitive impairment and traditional Chinese medicine preparations, which is applied in the directions of medical preparations, drug combinations, and pharmaceutical formulations containing active ingredients to achieve the effects of no toxic side effects, significant curative effects, and safe administration.

Inactive Publication Date: 2013-11-06
王蕾
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Currently, there is a lack of effective drugs for the disease

Method used

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  • Chinese medicinal preparation for treating mild cognitive impairment
  • Chinese medicinal preparation for treating mild cognitive impairment
  • Chinese medicinal preparation for treating mild cognitive impairment

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Embodiment 1 prepares the Chinese medicinal preparation for the treatment of mild cognitive impairment

[0022] The formula is: Shichangpu 15g, Curcuma 10g, Leulu 10g, Daxueteng 10g, Poria cocos 20g, Angelica 10g, Polygonatum 30g, Dilong 10g.

[0023] The preparation method is as follows:

[0024] (1) Take Acorus calamus and Chinese angelica, mix them, and steam distill them to obtain volatile oil and medicinal residue II, add β-cyclodextrin (20 g) to the volatile oil to obtain β-cyclodextrin inclusion compound I;

[0025] (2) Take Leulu, Earthworm, and Daxueteng, mix them, add 8 times the amount of ethanol, soak for 2 hours, filter to obtain the filtrate and filter residue, add 6 times the amount of ethanol to the filter residue, soak for 2 hours, and filter to obtain the filtrate With filter residue III, the filtrate of merging twice is standby;

[0026] (3) Get turmeric, Poria cocos and Rhizoma Polygonatum, mix with medicine residue II and filter residue III, add 1...

Embodiment 2

[0028] Embodiment 2 prepares the Chinese medicinal preparation for the treatment of mild cognitive impairment

[0029] The formula is: Shichangpu 20g, Curcuma 12g, Leulu 8g, Daxueteng 8g, Poria cocos 25g, Angelica 12g, Polygonatum 25g, Dilong 8g.

[0030] The preparation method is as follows:

[0031] (1) Take Acorus calamus and Chinese angelica, mix them, and steam distill them to obtain volatile oil and medicinal residue II, add β-cyclodextrin (20 g) to the volatile oil to obtain β-cyclodextrin inclusion complex I;

[0032] (2) Take Leulu, Earthworm, and Daxueteng, mix them, add 8 times the amount of ethanol, soak for 2 hours, filter to obtain the filtrate and filter residue, add 6 times the amount of ethanol to the filter residue, soak for 2 hours, and filter to obtain the filtrate With filter residue III, the filtrate of merging twice is standby;

[0033] (3) Get turmeric, Poria cocos and Rhizoma Polygonatum, mix with medicine residue II and filter residue III, add 10 ti...

Embodiment 3

[0035] Embodiment 3 prepares the Chinese medicinal preparation for the treatment of mild cognitive impairment

[0036] The formula is: Shichangpu 10g, Curcuma 8g, Leulu 12g, Daxueteng 12g, Poria cocos 15g, Angelica 8g, Polygonatum 35g, Dilong 12g.

[0037] The preparation method is as follows:

[0038] (1) Take Acorus calamus and Chinese angelica, mix them, and steam distill them to obtain volatile oil and medicinal residue II, add β-cyclodextrin (20 g) to the volatile oil to obtain β-cyclodextrin inclusion compound I;

[0039] (2) Take Leulu, Earthworm, and Daxueteng, mix them, add 8 times the amount of ethanol, soak for 2 hours, filter to obtain the filtrate and filter residue, add 6 times the amount of ethanol to the filter residue, soak for 2 hours, and filter to obtain the filtrate With filter residue III, the filtrate of merging twice is standby;

[0040] (3) Get turmeric, Poria cocos and Rhizoma Polygonatum, mix with medicine residue II and filter residue III, add 10 ...

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Abstract

The invention discloses a Chinese medicinal preparation for treating mild cognitive impairment. The Chinese medicinal preparation is prepared from the following Chinese herbal medicines in part by weight: 10 to 20 parts of acorus gramineus, 8 to 12 parts of curcuma aromatica, 8 to 12 parts of uniflower swisscentaury root, 8 to 12 parts of sargentg loryvine stem, 15 to 25 parts of tuckahoe, 8 to 12 parts of Chinese angelica, 25 to 35 parts of polygonatum and 8 to 12 parts of earthworm. The Chinese medicinal preparation is mainly used for treating mild cognitive impairment; the Chinese medicinal preparation is orally taken, a dose every time, and three times every day; and three months constitute a treatment course. Clinical research proves that the Chinese medicinal preparation has an obvious curative effect on mild cognitive impairment, does not have toxic and side effects on liver, kidney function, digestive system and hematopoietic system, and can be safely taken.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation for treating mild cognitive impairment. Background technique [0002] Mild cognitive impairment (MCI) is a transitional state between normal aging and dementia, and is a high risk factor for Alzheimer's disease, vascular dementia and other types of dementia. Studies have reported that the prevalence of dementia in people over 65 years old is 6.7%, has seriously threatened the quality of life of the elderly, and its pathogenesis is not yet fully understood. At present, it is believed that oxidative stress is a key factor in the development of mild cognitive impairment. Currently, there is a lack of effective drugs for the disease. Contents of the invention [0003] Aiming at the above prior art, the present invention provides a traditional Chinese medicine preparation for treating mild cognitive impairment. [0004] The present invention is achieved through the following technical s...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P25/28A61K35/64A61K35/62
Inventor 王蕾姬琳王兴臣
Owner 王蕾