Unlock instant, AI-driven research and patent intelligence for your innovation.

Caftaric acid as well as preparation method and applications thereof

A technology of caffeoyl tartaric acid and hydrochloric acid, which is applied in the fields of pharmaceutical formulations, separation/purification of carboxylic acid esters, medical preparations containing active ingredients, etc.

Inactive Publication Date: 2012-07-04
沈阳双鼎制药有限公司
View PDF5 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no method for extracting caffeoyl tartaric acid from Sophora cumulus

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0022] A preparation method using caffeoyl tartaric acid, comprising the following processing steps:

[0023] 1. Take bitter stalks, decoct and extract twice, add 8 times the amount of water for the first time, extract for 1-2 hours, add 6 times the amount of water for the second time, extract for 1 hour, combine the filtrates, and concentrate until the phase density is 60 The temperature is 1.10-1.20 at ℃, add hydrochloric acid to adjust the pH value to 3-4, add ethanol to 60-70% alcohol content, let stand for 12 hours, centrifugal filter (3000-4000 rpm), and separate the supernatant Liquid, recover ethanol under reduced pressure until the concentrated liquid has no alcohol smell, filter; adjust the pH value of the filtrate to 4-5, purify it through a pre-treated AB8 macroporous resin column, and elute with water (6 volumes of samples per volume of resin; The adsorption flow rate is 4 volumes / hour; the elution volume is 4 volumes of resin), collect the eluate, concentrate the...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
concentrationaaaaaaaaaa
Login to View More

Abstract

Caftaric acid is characterized by being extracted and separated from Ixeris sonchifolia. The invention discloses a method for extracting caftaric acid from Ixeris sonchifolia. The extracted caftaric acid can be used as the main active ingredient to prepare antibacterial and antiviral drugs; and caftaric acid is used to control the qualities of Ixeris sonchifolia and preparations thereof, and control the quality of caftaric acid preparations.

Description

technical field [0001] The invention relates to a production method of traditional Chinese medicine, in particular to a method for extracting and separating coffee tartaric acid from Kudiezi Chinese medicinal material. Background technique [0002] Caffeoyl tartaric acid is the raw material for preparing antibacterial and antiviral drugs. At present, there have been reports of extracting caffeoyl tartaric acid from Laverflower Chrysanthemum. The method is to add water to dissolve the raw material at a ratio of 1:2-5 to water, and add the filtrate to a chromatography column equipped with an acidic macroporous adsorption resin. Elute with three gradient eluents, collect the eluents, adjust the volume fraction of the acid to 0.05%-10%, desorb with 95% ethanol, and evaporate to dryness under reduced pressure to obtain caffeoyl tartaric acid. At present, there is no method for extracting caffeoyl tartaric acid from Sophora cumulus. Contents of the invention [0003] The objec...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): C07C69/732C07C67/48A61K31/216A61P31/04A61P31/12G01N30/02
Inventor 马占芝王淞林王学东生可心李志强
Owner 沈阳双鼎制药有限公司
Features
  • R&D
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com