98results about How to "Eliminate the purification process" patented technology

The invention relates to a segmented copolymer with a fully-saturated soft segment and a crystallizable hard segment and a preparation method of the segmented copolymer. A segmented copolymer with a fully-saturated polyisobutene segment as the soft segment and a crystallizable polystyrene or polyalkyl substituted styrene segment as the hard segment is synthesized by combining cationic polymerization of isobutene with cationic steric polymerization of styrene or alkyl substituted styrene cations, wherein as the hard segment has the crystallizability, physical crosslinking points are more stable, not only is a self-enhancement role achieved, but also the softening temperature of the segmented copolymer is effectively improved, and the melting point ranges from 150 DEG C to 210 DEG C; and according to the segmented copolymer, the use temperature is improved by 50-110 DEG C, and the heat resistance, the material size stability and the physical and mechanical properties are also improved.

The invention discloses a method for preparing a compound shown as the formula (I), which is characterized by comprising the following steps of: (1) carrying out hydroxyl protection on a compound shown as the formula (II) by using a first hydroxyl protecting group, and then, reacting with hydride to generate a compound shown as the formula (III); (2) carrying out hydroxyl protection on the compound shown as the formula (III) by using a second hydroxyl protecting group, and then, removing the first hydroxyl protecting group to obtain a compound shown as the formula (IV); (3) enabling the compound shown as the formula (IV) to carry out non-corresponding selective epoxidation reaction to generate a compound shown as the formula (V); (4) reacting the compound shown as the formula (V) with thecompound shown as the formula (VI) in a polar aprotic solvent to obtain a compound shown as the formula (VII); and (5) carrying out condensation, desilylation and oxidization on the compound shown asthe formula (VII) to generate the compound shown as the formula (I). In the general formulas of the compounds in each step, R1 is selected from naphthyl or any substituted naphthyl; R2 is selected from alkyl or benzyl of C1-C4; P is selected from hydroxyl protecting groups, such as 2-methoxyl propyl or p-methoxyl benzyl and the like; P' is a hydroxyl protecting group capable of resisting and removing P, such as benzyl; and X is selected from Cl, Br, I or benzyloxyl.

The invention provides carboxyl-containing high-refractive-index hyperbranched polyesteramide and a preparation method thereof, as well as application of the carboxyl-containing high-refractive-index hyperbranched polyesteramide to plastic modification, and belongs to the field of hyperbranched polymers. The reaction period can be shortened, the production process can be simplified, the cost can be reduced, and industrial large-scale production can be met. The preparation method comprises the following steps: adding an aromatic polycarboxylic/multi-anhydride monomer and a single amino and single hydroxyl monomer into a reactor, adding a catalyst into the reactor, and performing prepolymerization reaction under the protection of inert gas at the temperature of 80 to 180 DEG C for 0.5 to 48 hours to form a polymeric monomer; and then heating to 120 to 250 DEG C, performing reaction for 0.5 to 120 hours to obtain the carboxyl-containing high-refractive-index hyperbranched polyesteramide. The preparation method provided by the invention can be applied to the industrial production process of the carboxyl-containing high-refractive-index hyperbranched polyesteramide; the prepared carboxyl-containing high-refractive-index hyperbranched polyesteramide can resist the temperature higher than 350 DEG C and is relatively high in refractive index; as an improving agent, the carboxyl-containing high-refractive-index hyperbranched polyesteramide is applied to a plastic system; the mechanical property can be improved without affecting the transparency of the plastic system.

The invention belongs to the technical field of clean and efficient utilization of coal and relates to a novel process and a device for producing synthesis gas by coal, in particular to a method and a device for preparing synthesis gas by a coal particle/oxygen carrier chemical chain. In the method, double chemical chain is used to prepare the synthesis gas, the oxygen carrier undergoes a reduction reaction with the coal particles in an oxygen carrier gasifier and an oxidation reaction with air in an air reactor, and the synthesis gas is prepared by the cycle reaction of the oxygen carrier; the purification of the synthesis gas and the collection of CO2 are completed by using a CaCO3/CaO chemical chain; in the preparation of the synthesis gas by combined CaSO4/CaCO3 oxygen chemical chain,the purification and CO2 collection by using the CaCO3/CaO chemical chain are coupled in the preparation process of the synthesis gas by the oxygen carrier chemical chain; therefore, the preparation of the synthesis gas and the preparation of the two chemical chains for the purification of the synthesis gas and the CO2 collection are processed synchronously. The device has a simple structure and is based on a reliable principle; the energy utilization rate of the device is high; the gas prepared by the device has high quality; and the device causes little environmental pollution.

The invention provides a production method of diethanolisopropanolamine. The method comprises the following steps of S1, adding diethanol amine, water and acid into a reaction kettle; starting a stirring paddle for uniformly mixing each material; S2, in room temperature state, slowly adding epoxy propane; performing continuous stirring so that the epoxy propane and other materials can be uniformlymixed; raising the reaction temperature to 30 to 80 DEG C; S3, after all of the epoxy propane is added, performing heat insulation reaction on the reaction kettle for 30min to obtain a finished product of diethanolisopropanolamine. The diethanolisopropanolamine produced through the reaction of the diethanol amine and the epoxy propane can partially react with the epoxy propane under the water existence condition to produce quaternary amine alkali; the quaternary amine alkali is a strongly basic catalyst and can be used for catalyzing hydroxyls on the diethanolisopropanolamine to continuouslyreact with the epoxy propane to form ester. The acid can fast and effectively achieve the neutralization effect on the quaternary amine alkali in the reaction process; the reaction of the diethanolisopropanolamine in the direction of byproducts of eater is reduced.

The invention discloses a novel method for preparing a clopidogrel compound, which comprises the following steps: taking a compound shown in Formula (II) as a raw material, obtaining a compound shown in Formula (III) through optical resolution, obtaining a compound shown in Formula (IV) through substitution reaction of the compound shown in Formula (III), further obtaining a compound shown in Formula (V) by acetifying the compound shown in Formula (IV) to be salt, obtaining the final product, i.e. the lopidogrel compound shown in Formula (VI), through Mannich cyclization, and then generating salt by mixing the compound shown in Formula (VI) and sulfuric acid for reaction to obtain the target product (I). The method of the invention for preparing the clopidogrel compound has the advantages of readily available raw materials, low price, mild reaction condition, simple operation and high total yield, and is a novel integrated synthesis method applicable for industrial production of clopidogrel.

The invention relates to a preparation method of esomeprazole magnesium. The method comprises the steps that: esomeprazole is dissolved in an organic solvent; a potassium-containing alkali or salt is subjected to a reaction with esomeprazole, such that esomeprazole potassium is produced; and esomeprazole potassium is subjected to a displacement reaction with a magnesium salt, such that esomeprazole magnesium is prepared. The invention also relates to a refining method of esomeprazole magnesium. With the method provided by the invention, the purity of the prepared esomeprazole magnesium is higher than 99.9%, the yield is higher than 82%, and esomeprazole magnesium has good morphological stability. With the method, requirements by factory pharmacy for purity and yield can be satisfied.

The invention discloses a nano TiO2-diatomite composite photocatalyst and a preparation method thereof. The nano TiO2-diatomite composite photocatalyst is prepared from the following raw materials: raw diatomite, titanium tetrachloride, ammonium sulfate and iron salt, wherein the mass ratio of the raw materials is that the ratio of the raw diatomite to the titanium tetrachloride is 100 to (80-200), and the ratio of the titanium tetrachloride to the ammonium sulfate to the iron salt is 100 to (17-66) to (0-0.7). With the adoption of the composite photocatalyst, the problems in the prior art that the visible light utilization rate of the composite photocatalyst is low and the degradation capability on organic pollutants is low are solved, the visible light utilization rate of the composite photocatalyst is improved, and the degradation capability on the organic pollutants is improved.

The present invention relates to one kind of full cell catalyst with lipase activity and its preparation process. The intracellular lipase secreting full cell catalyst is prepared with the materials including saccharomycetes 0.7-1.2 wt%, diatomite 2.1-3.6 wt%, sodium alginate 2.0-2.3 wt%, calcium dichloride 0.5-0.8 wt%, and pH 7.7 Na2HPO4-NaH2PO4 buffer solution of 92.1-94.7 wt%, with the saccharomycetes to diatomite weight ratio being 1 to 3. The intracellular lipase secreting full cell catalyst is used to replace lipase in producing biological diesel oil, and has simple preparation process, easy product recovery, reusability and low production cost.

The invention discloses a synthesis method of hypericin. The synthesis method comprises the following steps of (a) dissolving emodin and tert-butanol salt into water, adding hydroquinone at a protective atmosphere, carrying out microwave irradiation, reacting at the temperature of 90-100 DEG C for 4-6h, then, transferring the product into a sealed vessel, continuing to react at the temperature of 120-140 DEG C for 8-12h, after finishing the reaction, adding an inorganic acid to regulate the pH value of the solution to 3-4, settling, filtering, washing, and drying, thereby obtaining raw hypericin at one step; and (b) dissolving the obtained raw hypericin and iodosobenzene substances into acetone, reacting at the temperature of 45-55 DEG C for 4-8h, filtering after finishing the reaction, collecting filtrate, carrying out evaporative concentration, washing, filtering and recrystallizing to obtain the hypericin. The hypericin obtained by using the synthesis method is high in purity and yield; and the synthesis method is simple in step, environment-friendly, reduced in cost and suitable for industrial production.

steps: employing an organic phase reaction system when reacted substrate fatty acids are saturation short chain fatty acids with a carbone chain length of C2-C4 and C12 high boiling long chain fatty acids, employing an non-solvent reaction system when reacted substrate fatty acids are saturation middle chain fatty acids with a carbone chain length of C5-C10, conversing and preparing a plurality of citronellyl esters materials by changing the ratio of alcohol to acid and the system water activity methods, obtaining products with a yield of 95 0n a short time. The invention has advantages of novel products, mild reaction temperature and environment friendly, moreover the reaction has selectivity and controllability, the reaction process is easy, the outcomes are easy to separate and the product quality is higher. The method of the invention has positive social benefit and economic value.

The invention discloses a cow heat-stress resistant feed additive. Saccharomyces cerevisiae (Sc) NAU-ZH-GY1 is applicable to prepare the cow heat-stress-resistant feed additive. The cow heat-stress-resistant feed additive, which is rich in glycerin, yeast live bacteria and microbial metabolites such as amino acids, vitamins and the like, is produced under the high-permeability condition by employing a continuously feeding manner for fermentation; and the cow heat-stress resistant feed additive is capable of cooperatively perform dual efficacy of glycerin and yeast, and is capable of substantially improving lactation yield, 4% fat corrected milk yield and milk fat percentage of cow under heat-stress condition, improving blood sugar concentration, reducing somatic cell number, concentration of non-esterified fatty acid and concentration of urea nitrogen in milk, supplementing energy for cows, alleviating body weight reduction, enhancing antioxidation capability, reducing HSP70mRNA level and effectively alleviating heat stress of cows.

The invention provides a preparation method of fluorocarbon/hydrocarbon mixed type cation surface active monomer, and the structural formula is shown in the description. The invention has the advantages of simple synthesis steps and products purification, high yield, safety usage and convenient storage. The fluorine containing surface active monomer can be copolymerized with a plurality of monomers for preparing various functional large molecules, and is widely applied to the fields of oil field exploitation, coating, fire-fighting, printing, electroplate, daily use chemical industry, medicine, etc.