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Traditional Chinese medicine composition for treating diarrhea-predominant irritable bowel syndrome

A technology of irritable bowel syndrome and composition, which is applied in the treatment of diarrhea-predominant irritable bowel syndrome and traditional Chinese medicine in the field of diarrhea-predominant irritable bowel syndrome. Significant curative effect, improvement of intestinal sensitivity, and short course of treatment

Active Publication Date: 2012-08-22
JIANGSU PROVINCE INST OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The quality of life of patients is affected to varying degrees, resulting in a large waste of medical and health resources

Method used

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Experimental program
Comparison scheme
Effect test

Embodiment

[0015] 1. Experimental materials:

[0016] 1.1 Animals: Experimental animals: 80 clean-grade SD rats, half male and half male, weighing 180±20g.

[0017] 1.2 Drug: Pinaverium bromide (Desolate) (Solvay Pharmaceutical Company, France), decoct the Chinese medicine composition of the present invention into water decoction, and concentrate the Chinese medicine decoction to 1 g / ml. After bottling the medicinal solution, put it in the refrigerator to save the spare traditional Chinese medicine (decoction), which is provided by Jiangsu Provincial Hospital of Integrated Traditional Chinese and Western Medicine. 5-HT, IL-8 ELISA kits were purchased from Shanghai Jianglai Bioengineering Co., Ltd.

[0018] 2. Experimental method

[0019] 2.1 Modeling method: 65 rats were taken, and a rat model of liver depression type intestinal sensitivity was established by rectal acetic acid stimulation method + tail pinch stimulation method. Intrarectal acetic acid stimulation was given daily for ...

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PUM

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Abstract

The invention discloses a traditional Chinese medicine composition for treating diarrhea-predominant irritable bowel syndrome. The traditional Chinese medicine composition comprises costustoot, golden thread, lesser galangal rhizome, baical skullcap root, green tangerine peel, divaricate saposhnikovia root, stir-fried largehead atractylodes rhizome, stir-fried white paeony root, tribulus terrestris, parslane herb, pomegranate rind and raw liquoric root according to a certain weight mixture ratio. Animal experiments prove that the traditional Chinese medicine composition disclosed by the invention can improve the intestinal sensitivity and the level of gastrointestinal hormone and inflammatory cell factor of diarrhea type IBS (irritable bowel syndrome) model rats, has the effect of multi-target treatment of diarrhea type IBS and can further soften liver, calm wind, clear heat, eliminate damp and effectively treat the diarrhea-predominant irritable bowel syndrome. The traditional Chinese medicine composition disclosed by the invention has the characteristics of scientific composition, exact curative effect, no side effects and the like.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine for treating diarrhea-type irritable bowel syndrome, in particular to a traditional Chinese medicine composition prepared by using specific components and proportions to treat diarrhea-type irritable bowel syndrome. [0002] Background technique [0003] Irritable bowel syndrome (Irritable Bowel Syndrome, IBS) is a chronic or recurrent abdominal pain, abdominal distension, accompanied by abnormal bowel habits and stool properties, but currently lacks intestinal function with abnormal morphological, bacteriological and biochemical indicators. handicap syndrome. IBS is one of the most common diseases of the digestive system, which belongs to a subtype of functional intestinal disorders (Functional Intestinal Disorders, FID). It affects the work to a certain extent and reduces the quality of life, which is more and more widely concerned by the medical field. [0004] The current point o...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9062A61P1/12
Inventor 田耀洲
Owner JIANGSU PROVINCE INST OF TRADITIONAL CHINESE MEDICINE