Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Traditional Chinese medicine for treating chronic suppurative otitis media, as well as application and preparation method of same

A technology of suppurative otitis media and traditional Chinese medicine, which is applied in the field of traditional Chinese medicine, can solve problems such as deafness and cast a shadow, and achieve the effects of not producing drug resistance, enhancing the body's immunity, and improving the body's anti-virus ability

Inactive Publication Date: 2012-09-19
JIASHAN YONGNING PLASTICS
View PDF5 Cites 5 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Western medicine believes that chronic suppurative otitis media is mainly caused by Pseudomonas aeruginosa, Escherichia coli, Proteus and Staphylococcus aureus. Otitis media is often caused by the mixed infection of aerobic and anaerobic bacteria, and most of them are anaerobic bacteria. Therefore, antibiotics, amikacin and other drugs are usually used for treatment. However, with the increase of drug-resistant strains, ototoxic The types of antibiotics are expanding year by year, which has cast a shadow over the previous antibiotic-based treatment of chronic suppurative otitis media, and the drugs with the highest susceptibility of common pathogenic bacteria in chronic suppurative otitis media are ototoxic drugs such as amikacin and gentamicin , these drugs, whether used systemically or locally, have the potential to cause deafness

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Traditional Chinese medicine for treating chronic suppurative otitis media, as well as application and preparation method of same

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0056] The present invention also provides a preparation method of the above-mentioned Chinese medicine composition. When the dosage form of the Chinese medicine composition is a capsule, the preparation method comprises the following steps,

[0057] In the first step, the components are mixed in proportion, placed in an ultrafine pulverizer and pulverized for 20 to 40 minutes, and the pulverized mixture is dissolved in ethanol with an alcohol concentration of 80% to 90%, and extracted twice by reflux ~4 times, filter, combine the filtrate, concentrate under reduced pressure to a paste with a relative density of 1.23~1.25 (70°C), wherein the amount of ethanol added is 2~4 times the quality of the mixture in the first step, and then dried, Use an ultrafine pulverizer to pulverize for 20 to 40 minutes, add 3 to 5 times the mass of the pulverized powder to dissolve it in water, and add 10% to 15% sodium hydroxide to help dissolve the powder while stirring, and adjust The pH value...

Embodiment 2

[0069] The Chinese medicine powder prepared by embodiment 2 the present invention

[0070] Rhubarb 15g, Phellodendron 40g, Gorgon fruit 20g, Ulzi 15g, Smilax 15g, Pokeweed 20g, Astragalus 25g, Reed root 30g, Daqingye 80g, Radix Paeoniae Rubra 25g, Saponaria thorn 15g, Moutan bark 25g, Qumai 15g , Anemarrhena 55g, Ophiopogon japonicus 25g, Lycium barbarum 25g, Chuanxiong 20g, Licorice 30g, Morus alba 15g, Catechu 10g and Woody 15g mixed, placed in a superfine pulverizer for 40 minutes, and the pulverized mixture was dissolved In the ethanol 1600g that alcohol concentration is 90%, reflux extraction 3 times, filter, combine filtrate, concentrate under reduced pressure to the paste that relative density is 1.25 (70 ℃), carry out drying subsequently, pulverize 40 minutes with superfine pulverizer, Add 2200g of water to the pulverized powder to dissolve, add 55g of sodium hydroxide to aid dissolution under stirring, adjust the pH value to 7, filter, add sulfuric acid with a concent...

Embodiment 3

[0071] Embodiment 3 Chinese medicine capsules prepared by the present invention

[0072] Rhubarb 15g, Phellodendron 40g, Gorgon fruit 20g, Ulzi 15g, Smilax 15g, Pokeweed 20g, Astragalus 25g, Reed root 30g, Daqingye 80g, Radix Paeoniae Rubra 25g, Saponaria thorn 15g, Moutan bark 25g, Qumai 15g , Anemarrhena 55g, Ophiopogon japonicus 25g, Lycium barbarum 25g, Ligusticum chuanxiong 20g, Licorice 30g, Morus alba 15g, Catechu 10g, Muxiang 15g, Turmeric 15g, Safflower 15g, mix them in an ultrafine pulverizer for 40 minutes , the pulverized mixture was dissolved in 1600 g of ethanol with an alcohol concentration of 90%, refluxed and extracted 3 times, filtered, and the combined filtrate was concentrated under reduced pressure to a paste with a relative density of 1.25 (70° C.), followed by drying and using an ultra- Pulverize with a micro pulverizer for 40 minutes, add 2200g of water to dissolve the pulverized powder, add 55g of sodium hydroxide to aid dissolution under stirring, adj...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a traditional Chinese medicine composition for treating chronic suppurative otitis media, which comprises rheum officinale, golden cypress, gorgon euryale seed, motherwort fruit, chinaroot greenbrier, pokeberry root, astragalus mongholicus, rhizoma phragmitis, folium isatidis, root of common peony, Chinese honeylocust fruit, coxtex moutan, dianthus superbus, rhizoma anemarrhenae, radix ophiopogonis, fructus lycii, ligusticum wallichii, liquorice, white mulberry root-bark, acacia catechu and costustoot. The traditional Chinese medicine provided by the invention has the advantages of strengthening the organism immunity, improving the organism antiviral ability, antibiosis and antiphlogosis and having no drug resistance when being used for treating chronic suppurative otitis media.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine for treating chronic suppurative otitis media. Background technique [0002] Chronic suppurative otitis media is a common multiple ear disease. It refers to the disease that produces pus on the bottom of the ear, causing perforation of the tympanic membrane and pus. It often coexists with chronic mastoiditis and is a common cause of deafness. Sexual deafness, often due to various reasons such as poor drainage of the middle ear, makes the disease lingering and difficult to heal. [0003] Chronic suppurative otitis media is often caused by untimely treatment or loss of treatment in the acute stage. It is generally believed that acute otitis media has not healed for 6 to 8 weeks, indicating that the lesion has become chronic. If the treatment is not timely, unreasonable, and incomplete, it is very easy to relapse or cause secondary...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/90A61P27/16
Inventor 许梅
Owner JIASHAN YONGNING PLASTICS
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com