Preparation method and application of trithiocarbonic acid ester compound containing isocyanate group
A technology of trithiocarbonate and isocyanate group, which is applied in the field of preparation of trithiocarbonate compounds, can solve the problems of inability to prepare the target compound containing isocyanate group, etc., and achieves strong operability, easy adjustment of sequence structure, and ease of use. The effect of adjustment
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Embodiment 1
[0067] (1) Preparation of 2-(n-butyltrithiocarbonate)propanecyanide
[0068] In general, the synthesis is divided into two steps, and the reaction scheme is as follows:
[0069]
[0070] C 4 h 9 SC(S)C(S)SC 4 h 9 +AIBN→2C 4 h 9 SC(S)SC(CH 3 ) 2 CN
[0071] Dissolve 3.85g of potassium tert-butoxide (BuOK) in 19.65g of tetrahydrofuran, and pour it into a 2000ml three-necked glass reaction kettle after completely dissolving. The solvent is 1000ml of n-heptane, and slowly add 3.09g of n-butyl at 5℃~10℃. Mercaptan, stirred mechanically for 30 minutes under nitrogen protection; then slowly added 2.63g carbon disulfide with a constant pressure funnel, the process continued for 20 minutes, continued to stir for 10 minutes after the addition, and then placed at 20°C~23°C for 4h, at 16°C~18°C Add 4.34 g of solid iodine particles in batches, the process lasts about 40 min, and react at room temperature 25°C for 15 h to generate a yellow-brown reaction product.
[0072] The y...
Embodiment 2
[0077] (1) Preparation of trithiocarbonate compounds containing isocyanate groups
[0078] Put the following reagents into a 250mL three-necked flask equipped with a reflux condenser, a nitrogen inlet, and a feed port: 20 grams of dioxane, 0.4617 grams of the product of the formula 16 structure prepared in Example 1, and 0.0183 grams of azodicyanovaleric acid and N,N-dimethylacrylamide 9.0372 grams. After the above device was passed through high-purity (99.99%) nitrogen for 1 hour, it was immersed in a 70°C water bath, and after 18 hours of reaction, an intermediate product was obtained; continue to add 15 grams of dioxane and 0.027 g of azodicyanovaleric acid to the three-necked flask. gram, 2.5 grams of isocyanate group-containing monomers with the structure of formula 10 and 5 grams of styrene (that is, the structure of formula 14), continue to react in a 75 ° C water bath for 12 hours, then cool down, stop the reaction, and obtain the product. The product was poured into ...
Embodiment 3
[0081] (1) Preparation of trithiocarbonate compounds containing isocyanate groups
[0082] The following reagents were dropped into a 250mL three-necked flask equipped with a reflux condenser, a nitrogen inlet, and a feed port: 18 grams of dioxane, 0.7067 grams of the product of the formula 16 structure prepared in Example 1, 0.0328 grams of azobisisobutyronitrile and N,N-Dimethacrylamide 9.0372 g. After passing high-purity (99.99%) nitrogen to the above device for 0.5 hours, immerse in a 70°C water bath, and react for 18 hours to obtain an intermediate product; continue to add 6 grams of dioxane and 0.0164 grams of azobisisobutyronitrile into the three-necked flask 1.39 grams of isocyanate group-containing monomers with the structure of formula 12 and 5.8 grams of n-butyl acrylate (that is, the structure of formula 13) were reacted in a 75°C water bath for 12 hours, then the temperature was lowered, and the reaction was stopped to obtain the product. The product was poured i...
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