Pawpaw seed extraction method, and liver-protecting drug containing pawpaw seed extract

An extraction method, the technology of papaya seeds, applied in the field of medicine, can solve the problems of aspartate aminotransferase insignificant effect, adverse reactions, water and sodium retention, etc., achieve safe and non-toxic removal, simple and easy process, and increase the effect of content

Inactive Publication Date: 2013-01-02
CHANGCHUN UNIV OF SCI & TECH
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  • Abstract
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Problems solved by technology

Also have some untoward reactions as described Chinese medicine preparation, although the schisandra extract wherein can effectively reduce the level of the alkaline phosphatase in the serum, but, easy rebound after drug withdrawal, the effect to aspartate aminotransferase is not obvious, some patients with chronic liver disease Elevation of aspartate aminotransferase after taking
Furthermore, the long-term curative effect is poor
In addition, although glycyrrhizin has anti-inflamm

Method used

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  • Pawpaw seed extraction method, and liver-protecting drug containing pawpaw seed extract
  • Pawpaw seed extraction method, and liver-protecting drug containing pawpaw seed extract
  • Pawpaw seed extraction method, and liver-protecting drug containing pawpaw seed extract

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Embodiment Construction

[0014] The specific implementation method of the papaya seed extract extraction method of the present invention is as follows. The papaya seeds are dry and mature seeds of the Rosaceae plant Begonia spp. Grind the dried papaya seeds with a grinder, pass the crushed matter through a 40-mesh sieve, take 100 g of the sifted papaya seed crushed matter, and take 80-90% ethanol solution of 5-6 times the volume of 100 g of the papaya seed crushed matter. Add the pulverized papaya seeds into the ethanol solution, heat and reflux for extraction for 2-5 hours; or ultrasonically extract for 25-35 minutes at a temperature of 35-45°C. Then filter while hot to get residue and filtrate. The slag is then treated 2 to 3 times in the same manner, that is, the slag is added to an ethanol solution for heating under reflux or ultrasonic extraction. The filtrates of each time are combined, and the filtrate is a crude extract solution containing papaya seed oil, terpene components and steroid comp...

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Abstract

The invention discloses a pawpaw seed (semen chaenomelis) extraction method, and a liver-protecting drug containing pawpaw seed extract. In existing extraction method, the chemical components of extract are not concentrated on effective liver-protecting components; and no existing liver-protecting drug takes pawpaw seed extract as liver-protecting components. The inventive extraction method includes adding pulverized pawpaw seed into ethanol solution; performing reflux extraction or ultrasonic extraction to obtain crude extractive solution containing effective liver-protecting components (pawpaw seed oil, terpene components and steroid components); recovering ethanol in the crude extractive solution under reduced pressure, extracting effective liver-protecting components in residue with ethyl acetate; and recovering ethyl acetate under reduced pressure to obtain solid pawpaw seed extract composed of pawpaw seed oil, terpene components and steroid components. The liver-protecting drug contains effective liver-protecting components 0.1-100 wt%.

Description

technical field [0001] The invention relates to a method for extracting papaya seed extract and a liver-protecting medicine containing the papaya seed extract. The use of the papaya seed extract proposed by the method of the invention in the liver-protecting medicine belongs to the technical field of medicine. Background technique [0002] The side effects of chemicals make them harmful to the human body in the process of treating diseases. In view of this, natural medicines began to rise. As an important natural medicine, traditional Chinese medicine has accumulated a lot of clinical experience after years of use and achieved remarkable curative effect. Among them, papaya is a commonly used traditional Chinese medicine, which is flat in nature, slightly cold, sweet in taste, and returns to the liver and spleen meridians. According to the records of "Compendium of Materia Medica", papaya is mainly used to treat dampness, beriberi, cholera vomiting, and continuous tendons. ...

Claims

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Application Information

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IPC IPC(8): A61K36/732A61P1/16A61K131/00
Inventor 陈玉娟王巍王会堂
Owner CHANGCHUN UNIV OF SCI & TECH
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