Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Acitretin and pyridaben emulsion-in-water pesticide and production method thereof

A technology of avidaben-in-water emulsion, which is applied in the field of avidaben-in-water emulsion insecticide and its production process, which can solve the problem of limited development, poor adhesion and penetration, and reduction of active ingredients in products Content and other issues, to achieve the effect of simple production process and stable dosage form

Inactive Publication Date: 2013-01-23
王龙华
View PDF0 Cites 9 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Emulsion-in-Water products have some technical problems: 1) The storage stability time is short: the normal storage time of pesticides is 2-3 years, while the normal storage time of Emulsion-in-Water is 1 year Left and right; 2) Delamination phenomenon is prone to occur: it will cause demulsification due to temperature, physical and chemical changes of the original drug and additives, ultraviolet rays, time, water quality and other reasons, that is, the separation of water and solvent to form stratification; 3) Precipitation is prone to occur: due to the decomposition of the auxiliary agent and the original drug, the original drug is poured out of the preparation, forming a rice grain or crystal-like substance and sinking to the bottom, which greatly reduces the efficacy and effectiveness of the product. 4) It is difficult to solve the problem of pesticide synergy: since water is the main solvent, the formation of water emulsion is a principle of dynamic stability. Thione, etc., are extremely unstable in this dosage form. Therefore, the surface swelling force of the normal dosage form of the water-emulsion is almost the same as that of water. Poor adhesion and penetration are the biggest problems of the water-emulsion, and it is difficult to improve the drug resistance of the product. 5) Emulsion in water is easy to freeze in winter, especially in northern China where the temperature is lower than 15°C, which greatly limits the development of this formulation

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Abamectin 0.5%, pyridaben 10%, xylene 25%, nonylphenol polyoxyethylene ether 1%, phenylethylcumylphenol polyoxyethylene ether 3%, benzyldimethylphenol polyoxyethylene ether Oxyethylene ether 2%, calcium dodecylbenzene sulfonate 1%, and the balance made up with water.

[0027] Results: 1. The dosage form is stable, and it can be stored at room temperature for more than 2 years; 2. The active ingredients do not degrade, and the average degradation rate is 0.1% when stored in heat at 52℃±2 for 15 days; stored in cold storage at -10℃±2 for 15 days without freezing , no crystallization, and the hydrolysis rate is 0.01%; 3. Significant synergy, up to 70%.

[0028] Example 2

Embodiment 2

[0030] Abamectin 0.6%, pyridaben 12%, xylene 30%, nonylphenol polyoxyethylene ether 2%, phenylethylcumylphenol polyoxyethylene ether 4%, benzyldimethylphenol polyoxyethylene ether Oxyethylene ether 3%, calcium dodecylbenzene sulfonate 2%, and the balance water to make up.

[0031] Results: 1. The dosage form is stable, and it can be stored at room temperature for more than 2 years; 2. The degradation rate of active ingredients is very low. The average degradation rate is 0.5% when stored in heat at 52℃±2 for 15 days; when stored in cold storage at -10℃±2 for 15 days. No freezing, no crystallization, the hydrolysis rate is 0.05%; 3. The synergistic effect is remarkable, and the synergistic effect reaches 66%.

[0032] Example 3

Embodiment 3

[0034] Results: 1. The dosage form is stable, and it can be stored at room temperature for more than 2 years; 2. The average degradation rate is 0.1% when stored in heat at 52°C±2 for 15 days; in cold storage at -10°C±2 for 15 days, it does not freeze, does not crystallize, and hydrolyzes The rate is 0.04%; 3. Significant synergies, up to 52%.

[0035] Example 4

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses an acitretin and pyridaben emulsion-in-water pesticide and a production method thereof. The pesticide comprises the following components in percentage by weight: 0.4-0.6% of avermectin, 8-12% of pyridaben, 20-30% of dimethylbenzene, 0.5-2% of nonylphenol ethoxylate, 2-4% of pesticide emulsifier No. 600-2, 1-3% of pesticide emulsifier No. 400, 0.5-2% of calcium dodecylbenzene sulfonate and the balance of water. The production method comprises the steps of weighing, active compound dissolving, mother liquor preparation and shearing. The pesticide has the advantages that the formulation is stable, the synergism is obvious, and the production method is simple.

Description

technical field [0001] The invention relates to a water-emulsion insecticide, in particular to a water-emulsion insecticide and a production process thereof, belonging to the field of water-emulsion insecticides. Background technique [0002] Emulsion-in-Water dosage form with the international code Ew, also known as concentrated emulsion, is a preparation in which the liquid or the liquid pesticide technical compound prepared by mixing with a solvent is dispersed in water with small droplets of 0.5-1.5 microns, and its appearance is milky white milk-like liquid. Water emulsion uses a large amount of water as the main solvent, saving natural resources. It is an internationally recognized environmentally friendly water-based formulation, with low cost of additives and simple production equipment. It is one of the main formulations in the current development of pesticides. [0003] There are some technical problems in water-emulsion products: 1) short storage stability time: t...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A01N43/90A01N43/58A01N25/04A01P7/04
Inventor 邓万平王龙华
Owner 王龙华
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com