Compound stemona cough stopping medicine and its preparation method

A cough medicine and Baibu technology, applied in the field of compound Baibu cough medicine and preparation thereof, can solve the problems of large dosage of granules, easy moisture absorption of granules, easy occurrence of agglomeration, etc., and achieves good taste and elegant appearance. , Quality controllable effect

Active Publication Date: 2005-01-05
JIANGSU KANION PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The disadvantage is that the preparation is a granule, the dosage form is relatively backward, the dosage of the granule is large, and the granule contains a large amount of sucrose; the granule is easy to absorb moisture, and it is prone to agglomeration during storage

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] Example 1. A compound pertussis antitussive medicine, which is a medicament made from the following raw materials by weight content, and the dosage form is an effervescent tablet (unit: gram)

[0051] Chinese herbal medicine raw materials:

[0052] 100 pieces (honey roasted) 100 bitter almond 50 platycodon 50

[0053] Mulberry 50 Ophiopogon 25 Anemarrhena 25

[0054] Scutellaria baicalensis 100 tangerine peel 100 licorice 25

[0055] Araceae (prepared) 25 Fructus aurantium (stir-fried) 50

[0056] medical supplements:

[0057] Citrate 80 Polyethylene Glycol 6000 20 Sodium Bicarbonate 80.

Embodiment 2

[0058] Example 2. The preparation method of a compound pericyte cough medicine described in embodiment 1, the steps are as follows:

[0059] (1) Take the 11-flavored Chinese herbal medicine raw materials, respectively add 10 times and 8 times the amount of water to decoct twice for 2 hours each time, combine the decoction, filter, and decompress the filtrate at -0.09MPa and 80°C Concentrate until a clear paste with a relative density of 1.35 measured at 50°C, then vacuum-dry it below 70°C, pulverize into fine powder, add fine citric acid powder, mix well, granulate with absolute ethanol, and dry; Separately dissolve polyethylene glycol 6000 in absolute ethanol, add sodium bicarbonate to form granules, and dry;

[0060] (2) Take the above-mentioned dried two kinds of granules and mix them evenly, add appropriate amount of sodium cyclamate and flavor, and press them into 100 tablets to obtain the finished compound pericytus cough effervescent tablets.

Embodiment 3

[0061] Example 3. A compound pertussis antitussive medicine, which is a medicament made from the following raw materials with the following weight percentages. The dosage form of the medicament is an effervescent tablet.

[0062] Chinese herbal medicine raw materials:

[0063] Honey Roasted Strawberry 13% Bitter Almond 6.5% Platycodon 6.5%

[0064] Mulberry 6.5% Ophiopogon 3% Anemarrhena 3%

[0065] Scutellaria baicalensis 13% dried tangerine peel 13% licorice 3%

[0066] Araceae 3% Fried Fructus Aurantii 6.5%;

[0067] medical supplements:

[0068] Fumaric acid 10% polyethylene glycol 6000 3% sodium bicarbonate 10%.

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Abstract

A Chinese medicine in the form of effervescent tablet for treating cough is prepared from 11 Chinese-medicinal materials including bitter almond, mulberry bark, tangerine peel, liquorice root, etc and 3 medicinal additives: citric acid, dicarbonate and polyethanediol 6000.

Description

Technical field [0001] The invention relates to a medicine made from Chinese herbal medicines, in particular to a compound pericyte cough relieving medicine; the invention also relates to a preparation method of the medicine. Background technique [0002] In the prior art, compound Baibuzhike granules is a classic Chinese patent medicine. It is made into granules of 11 medicines such as honey-dried babu, bitter almond, platycodon, mulberry bark, Ophiopogon japonicus, Zhimu, scutellaria, tangerine peel, licorice, araceae, and fried citrus aurantium. When used, it is taken with boiling water, 10 times each time. -20 grams, 2-3 times a day, reduce for children. Each bag of 10 grams is equivalent to 6 grams of original medicinal materials. The compound pertussis cough granule has the effect of clearing lungs and relieving cough, and is used for clinical treatment of cough with lung heat, yellow and thick sputum, and whooping cough. The disadvantage is that the prep...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61K9/46A61P11/14
Inventor 肖伟戴翔翎凌娅张辉尚强王振中
Owner JIANGSU KANION PHARMA CO LTD
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