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Combined multifunctional bioreactor

A bioreactor, multifunctional technology, applied in biochemical instruments, biochemical equipment and methods, tissue cell/virus culture devices, etc., can solve the problems of culture growth and development not meeting clinical requirements, etc. Effect

Inactive Publication Date: 2014-08-06
TIANJIN UNIVERSITY OF TECHNOLOGY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the use of various bioreactors in the prior art optimizes the growth of cultures, the growth and development of cultures still do not meet clinical requirements

Method used

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  • Combined multifunctional bioreactor
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Examples

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Embodiment

[0025]A rolling and sliding loading device for cartilage tissue engineering, consisting of a base rail mechanism, a linear motor, a culture chamber, a compression adjustment mechanism, a rolling mechanism, and a sliding mechanism. The base rail mechanism includes a base 1, a boss 2 and a guide rail 3, The boss 2 is fixed to the base 1, and the guide rail 3 is fixed on the boss 2; the linear motor includes a motor stator 4, a motor mover a5, a motor mover b6, a slide a7 and a slide b8, and the motor stator 4 is fixed to the base 1, The concave sliding table a7 and sliding table b8 are respectively fastened to the guide rail 3 and form a sliding fit with the guide rail 3. The motor mover a5 and the electric mover b6 are respectively fixed with the sliding table a7 and the sliding table b8; the cultivation room and the compression adjustment mechanism It includes a compression platform 9, a compression adjustment frame 10, a baffle plate 11, a compression platform chassis 12, an u...

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Abstract

The invention provides a combined multifunctional bioreactor. The bioreactor comprises a base guide rail mechanism, a linear motor, a culture room and compression regulating mechanism, a rolling mechanism, a sliding mechanism and a tension and compression mechanism, wherein the base guide rail mechanism comprises a base, a lug boss and a guide rail; the linear motor comprises a motor stator, motor rotors a and b, and sliding tables a and b; the culture room and compression regulating mechanism comprises a compression platform, a regulating frame, a baffle plate, a compression platform bottom frame, an upper wedge-shaped sliding block, a lower wedge-shaped sliding block, a compression regulating lead screw, a reset spring and a culture room; the rolling mechanism comprises a sliding table bracket a, a connecting rod a, a connecting rod head and a roller; the sliding mechanism comprises a sliding table bracket b and a connecting rod b; and the tension and compression mechanism comprises a tension and compression platform, a tension and compression chamber, tension and compression rods a and b, and a tension and compression head assembly. The combined multifunctional bioreactor has the advantages that the device precision is improved by taking the linear motor as a power source, a loading mechanism can be flexibly disassembled and assembled to form a rolling and sliding loading device and a tension and compression loading device, and multiple mechanical environments are provided for cell culture and tissue repair.

Description

technical field [0001] The invention relates to a bioreactor in biomedical engineering, in particular to a combined multifunctional bioreactor. Background technique [0002] In recent years, joint pain, mobility impairment and even complete loss of joint function due to cartilage degeneration or defect have become a difficult problem in medical treatment. Although many new technologies and methods are used in clinical treatment, there is still no suitable method to obtain satisfactory therapeutic effect. [0003] At present, cartilage tissue engineering is becoming an ideal method for permanently repairing tissue defects, and great progress has been made in seed cells, scaffold materials, growth regulators, and tissue construction. There are currently four types of bioreactors commonly used for cell culture, tissue and cell-stent culture cultivation and maintenance, namely: static bioreactors, rotating culture flask bioreactors, rotating wall bioreactors and perfusion biore...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12M3/00
Inventor 张春秋王大帅路军高丽兰刘清董心
Owner TIANJIN UNIVERSITY OF TECHNOLOGY
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