Anti-cold pharmaceutical composition and preparation method thereof
A composition and drug technology, which is applied in the direction of drug combination, pharmaceutical formula, heterocyclic compound active ingredients, etc., can solve the problems of slow curative effect and no direct symptomatic effect, and achieve the effect of definite curative effect, less adverse reactions and increased convenience
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Embodiment 1
[0061] Embodiment 1: the medicinal composition of anti-cold
[0062] 1. Raw materials:
[0063]
Weight (kg)
weight percentage (%)
Daqingye
500
32.049
nepeta
400
25.639
Hyakube
260
16.665
Acetaminophen
280
17.947
Clemastine Fumarate
0.335
0.021
Low-substituted hydroxypropyl cellulose
75.0
4.807
[0064] lactose
25.0
1.602
Polyvinylpyrrolidone
16.5
1.058
Magnesium stearate
3.3
0.212
total
1560.135
100
[0065] 2. Preparation method:
[0066] 1) Weigh each component according to the ratio of raw materials, and set aside;
[0067] 2) Take Schizonepeta, add 8 times the weight of Schizonepeta in water, soak for 24 hours, extract the volatile oil by steam distillation, the extraction time is 3 hours, store the volatile oil in another container, recover the residue, and set aside;
[0068] 3) deco...
Embodiment 2
[0071] Embodiment 2: the pharmaceutical composition of anti-cold
[0072] 1. Raw materials:
[0073]
Weight (kg)
weight percentage (%)
Daqingye
650
38.915
nepeta
300
17.961
Hyakube
400
23.948
Acetaminophen
200
11.974
Clemastine Fumarate
0.5
0.030
Low-substituted hydroxypropyl cellulose
75.0
4.490
lactose
25.0
1.497
Polyvinylpyrrolidone
16.5
0.988
Magnesium stearate
3.3
0.198
total
1670.3
100
[0074] 2. Preparation method:
[0075] 1) Weigh each component according to the ratio of raw materials, and set aside;
[0076] 2) Take Schizonepeta, add 6 times the weight of Schizonepeta in water, soak for 36 hours, extract the volatile oil by steam distillation, the extraction time is 4 hours, collect the volatile oil in another device, recover the residue, and set aside;
[0077] 3) decocting the Schizonep...
Embodiment 3
[0080] Embodiment 3: the medicinal composition of anti-cold
[0081] 1. Raw materials:
[0082]
Weight (kg)
weight percentage (%)
Daqingye
350
23.028
nepeta
500
32.897
Hyakube
150
9.870
Acetaminophen
400
26.318
Clemastine Fumarate
0.1
0.007
Low-substituted hydroxypropyl cellulose
75.0
4.935
lactose
25.0
1.645
Polyvinylpyrrolidone
16.5
1.086
Magnesium stearate
3.3
0.217
total
1519.9
100
[0083] 2. Preparation method:
[0084] 1) Weigh each component according to the ratio of raw materials, and set aside;
[0085] 2) Take Schizonepeta, add 8 times the weight of Schizonepeta in water, soak for 24 hours, extract the volatile oil by steam distillation, the extraction time is 2 hours, store the volatile oil in another container, recover the residue, and set aside;
[0086] 3) decocting the Schizonepeta r...
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