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Anti-cold pharmaceutical composition and preparation method thereof

A composition and drug technology, which is applied in the direction of drug combination, pharmaceutical formula, heterocyclic compound active ingredients, etc., can solve the problems of slow curative effect and no direct symptomatic effect, and achieve the effect of definite curative effect, less adverse reactions and increased convenience

Active Publication Date: 2013-03-20
蚌埠丰原涂山制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although traditional Chinese medicine is widely accepted by the Chinese people and has fewer adverse reactions and high safety, it usually has no direct symptomatic effect, and the curative effect occurs slowly

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0061] Embodiment 1: the medicinal composition of anti-cold

[0062] 1. Raw materials:

[0063]

Weight (kg)

weight percentage (%)

Daqingye

500

32.049

nepeta

400

25.639

Hyakube

260

16.665

Acetaminophen

280

17.947

Clemastine Fumarate

0.335

0.021

Low-substituted hydroxypropyl cellulose

75.0

4.807

[0064] lactose

25.0

1.602

Polyvinylpyrrolidone

16.5

1.058

Magnesium stearate

3.3

0.212

total

1560.135

100

[0065] 2. Preparation method:

[0066] 1) Weigh each component according to the ratio of raw materials, and set aside;

[0067] 2) Take Schizonepeta, add 8 times the weight of Schizonepeta in water, soak for 24 hours, extract the volatile oil by steam distillation, the extraction time is 3 hours, store the volatile oil in another container, recover the residue, and set aside;

[0068] 3) deco...

Embodiment 2

[0071] Embodiment 2: the pharmaceutical composition of anti-cold

[0072] 1. Raw materials:

[0073]

Weight (kg)

weight percentage (%)

Daqingye

650

38.915

nepeta

300

17.961

Hyakube

400

23.948

Acetaminophen

200

11.974

Clemastine Fumarate

0.5

0.030

Low-substituted hydroxypropyl cellulose

75.0

4.490

lactose

25.0

1.497

Polyvinylpyrrolidone

16.5

0.988

Magnesium stearate

3.3

0.198

total

1670.3

100

[0074] 2. Preparation method:

[0075] 1) Weigh each component according to the ratio of raw materials, and set aside;

[0076] 2) Take Schizonepeta, add 6 times the weight of Schizonepeta in water, soak for 36 hours, extract the volatile oil by steam distillation, the extraction time is 4 hours, collect the volatile oil in another device, recover the residue, and set aside;

[0077] 3) decocting the Schizonep...

Embodiment 3

[0080] Embodiment 3: the medicinal composition of anti-cold

[0081] 1. Raw materials:

[0082]

Weight (kg)

weight percentage (%)

Daqingye

350

23.028

nepeta

500

32.897

Hyakube

150

9.870

Acetaminophen

400

26.318

Clemastine Fumarate

0.1

0.007

Low-substituted hydroxypropyl cellulose

75.0

4.935

lactose

25.0

1.645

Polyvinylpyrrolidone

16.5

1.086

Magnesium stearate

3.3

0.217

total

1519.9

100

[0083] 2. Preparation method:

[0084] 1) Weigh each component according to the ratio of raw materials, and set aside;

[0085] 2) Take Schizonepeta, add 8 times the weight of Schizonepeta in water, soak for 24 hours, extract the volatile oil by steam distillation, the extraction time is 2 hours, store the volatile oil in another container, recover the residue, and set aside;

[0086] 3) decocting the Schizonepeta r...

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Abstract

The invention relates to an anti-cold pharmaceutical composition and a preparation method thereof. The pharmaceutical composition comprises the following pharmaceuticals: p-acetamidophenol, clemastine fumarate, folium isatidis, schizonepeta and stemona japonica. The anti-cold pharmaceutical composition is obvious in curative effect, low in cost and capable of providing a selection of treatment pharmaceuticals.

Description

technical field [0001] The invention relates to a pharmaceutical composition, in particular to an anti-cold pharmaceutical composition and a preparation method thereof. Background technique [0002] Western medicine believes that colds, commonly known as colds or acute nasal catarrh, are caused by infection with a variety of pathogens. Infect. The whole body may have chills, fatigue, weakness, general malaise, and sometimes mild fever, headache, limb pain, back pain, etc.; nasal cavity and turbinate mucosa congestion, runny nose, edema, loss of sense of smell; sneezing; pharynx may have Symptoms include mild to moderate congestion, sore throat, dry throat, hoarseness and coughing. Influenza is an acute respiratory infectious disease caused by influenza virus, with sudden onset and severe local and systemic symptoms. It is divided into four types: simple type, pneumonia type, gastrointestinal type and neurological type. [0003] According to traditional Chinese medicine, a...

Claims

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Application Information

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IPC IPC(8): A61K36/904A61P11/00A61P31/16A61K31/167A61K31/40
Inventor 马其胜张勇尹群孙鹏朱学娟李保琴
Owner 蚌埠丰原涂山制药有限公司
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