Medicinal compound rigid sheet for cold stamping forming

Abstract

The invention discloses a medicinal compound rigid sheet for cold stamping forming, which comprises a first two-way stretching nylon film layer (2), an aluminium foil layer (1) and a second two-way stretching nylon film layer (3), wherein the first two-way stretching nylon film layer (2) is above the aluminium foil layer (1); and the second two-way stretching nylon film layer (3) is below the aluminium foil layer (1). By using the compound rigid sheet disclosed by the invention to carry out cold stamping forming, a formed product has ultra-high flatness, the barrier property is high, the depth of a formed bubble cap is high, and the rejection rate is reduced.

Description

technical field [0001] The invention relates to the field of pharmaceutical blister packaging, in particular to a cold stamping-formed pharmaceutical composite hard sheet. Background technique [0002] The blister packaging of medicines, also known as blister packaging, is to place the medicines in the pits (called blisters or blisters) of the packaging hard sheet formed by vacuum blister molding or cold stamping, and then coated with heat The medicine packaging of the sealing layer is heat-sealed with aluminum foil to form a unit package, so that the medicine is safely protected. [0003] The covering material of pharmaceutical blister packaging is generally aluminum foil (called aluminum foil for pharmaceutical blister packaging), and the blister substrate is traditionally made of polyvinyl chloride (PVC) hard sheet. However, with the continuous development of the pharmaceutical industry, this traditional packaging method has exposed obvious defects, that is, due to the l...

AI Technical Summary

Problems solved by technology

[0004] However, with the diversification of pharmaceutical blister packaging, it is difficult for ordinary three-layer cold-stamped composite hard sheets to meet higher requirements, such as requiring extremely high flatness after cold-stamping to be suitable for liquid filling, and It is required to have extremely high barrier properties after cold stamping

Due to the asymmetric structure of the ordinary three-layer structure cold stamping composite hard sheet, the stress imbalance between the biaxially stretched nylon film layer and the PVC layer on both sides of the aluminum foil layer due to different materials, resulting in the subsequent processing and cold stamping. After that, it is prone to warping and cannot meet the high flatness requirements after cold stamping

Moreover, due to the asymmetric structure, there is an obvious stress difference between the two sides of the aluminum foil layer during cold stamping. When the stress difference on both sides reaches a certain value, the aluminum foil layer will break, and tiny pinholes can be observed under the pinhole detector. Blister rupture even occurs, which affects the actual barrier properties of blister packaging and has a high reject rate

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