Pharmaceutical composition for preventing ONFH (Osteonecrosis of Femoral Head) after child DDH (Developmental Dysplasia of Hip) operation

A technique for osteonecrosis of the femoral head and hip joints, applied in drug combinations, bone diseases, pharmaceutical formulations, etc., can solve problems such as internal fixation fracture and internal fixation loosening, and achieve the effect of definite curative effect and prevention of femoral head necrosis

Active Publication Date: 2013-04-03
NANTONG HONGCI PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

4. Internal fixation fracture: internal fixation loosening may occur after surgery, and internal fixation may break due to trauma and other reasons

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Example 1 Preparation of Chinese medicine granules

[0034] The first step is to prepare clear powder:

[0035] 1) Preparation: Weigh out 2 kg of washed burdock seeds and 1 kg of Ligusticum chuanxiong according to the prescribed amount for use;

[0036] 2) Decoction: add water to decoct, add water to each pot of the first decoction 8 times the total amount of medicinal materials, keep it for 3 hours after heating and boiling, the extract is filtered through a 200-mesh filter into the sedimentation tank; the second decoction adds 4 times the amount of medicinal materials The water is heated and extracted and kept boiling for 3 hours. The extract is filtered through a 200-mesh filter into the precipitation tank;

[0037] 3) Sedimentation: The extract is precipitated in the sedimentation tank for 24 to 36 hours, the supernatant is extracted and filtered through a 200-mesh filter to a three-effect evaporator, and the sediment is treated as waste;

[0038] 4) Concentration: When the ...

Embodiment 2

[0043] Example 2 Preparation of Traditional Chinese Medicine Oral Liquid

[0044] 1) Preparation: Weigh 3 kg of clean burdock seeds and 1 kg of chuanxiong according to the prescribed amount for use;

[0045] 2) Decoction: add water to decoct, add water to each pot of the first decoction 8 times the total amount of medicinal materials, keep it for 3 hours after heating and boiling, the extract is filtered through a 200 mesh filter into the sedimentation tank; the second decoction adds 4 times the amount of medicinal materials The water is heated and extracted and kept boiling for 3 hours. The extract is filtered through a 200-mesh filter into the precipitation tank;

[0046] 3) Sedimentation: The extract is precipitated in the sedimentation tank for 24 to 36 hours, the supernatant is extracted and filtered through a 200-mesh filter to a three-effect evaporator, and the sediment is treated as waste;

[0047] 4) Concentration: When the supernatant is concentrated in a three-effect evapor...

Embodiment 3

[0051] Example 3 Study on the curative effect of the medicine of the present invention combined with surgery to treat children with developmental dislocation of the hip

[0052] 34 cases of pediatric developmental dislocation of the hip, aged from 2 to 14 years, with an average age of 7.1 years, are all developmental dislocations of the hip. The main symptoms include: (1) claudication: children stand and walk later than normal children. At the time, the affected limb was shortened and limp. If bilateral dislocation, buttocks shrug after standing, waist protruding forward, walking with duck step swing; (2) Deformity: Compared with normal lower limbs, unilateral affected limbs show shortening deformities, often adduction deformities and abductions Time is limited; (3) The greater trochanter moves up: the upper point of the greater trochanter moves up in children, more than 1cm beyond the Nelaton line. All patients were randomly divided into test group and control group. There was ...

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PUM

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Abstract

The invention discloses a pharmaceutical composition for preventing ONFH (Osteonecrosis of Femoral Head) after a child DDH (Developmental Dysplasia of Hip) operation, relating to the technical field of traditional Chinese medicine. The pharmaceutical composition for preventing ONFH after DDH operation is prepared from traditional Chinese medicinal materials in parts by weight of: 15-30 parts of achene of great burdock and 8-13 parts of ligusticum wallichii. The pharmaceutical composition cooperates with an operation to treat the DDH, so that the pharmaceutical composition can prevent occurrence of ONFH efficiently, achieves exact curative effects and is worth popularizing clinically.

Description

Technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a pharmaceutical composition for preventing femoral head necrosis after pediatric developmental dislocation of the hip. Background technique [0002] Developmental Dysplasia of the Hip (DDH) is a disease of unilateral or bilateral hip joint instability and poor alignment of the femoral head and acetabulum due to genetic, breech delivery, leg binding and other factors . Early reduction can restore the normal anatomical relationship of the femoral head in time, which is beneficial to development and can increase the stability of the hip joint. It is generally believed that the treatment effect is best within one year of age. In the treatment of developmental dislocation of the hip in children, the pelvic and femoral deformities must be corrected at the same time, and combined surgery can achieve good results. However, the operation of developmental dislocation of...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/28A61P19/08
Inventor 臧玲
Owner NANTONG HONGCI PHARMA
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