Traditional Chinese medicine composition for curing tuberculous exadative pleurisy and preparation method thereof

A technology of exudative pleurisy and composition, which is applied in the field of traditional Chinese medicine, can solve problems such as difficult to be completely cured, residual sequelae, decreased fibrinolytic activity and collagenase activity, etc., reduces the probability of pleural hypertrophy or adhesion, and alleviates pleural fluid absorption Adverse reactions, the effect of reducing pleural adhesions

Inactive Publication Date: 2013-04-17
CHONGQING XUANNU BIOTECH
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  • Abstract
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  • Claims
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Problems solved by technology

[0005] Conventional treatment methods for tuberculous exudative pleurisy mainly include anti-tuberculosis drugs, hormones, puncture and drainage, and/or pleural injection, etc. Oral administration of anti-tuberculosis drugs and hormones, combined with drainage of pleural effusion, can reduce pleural damage, Although the curative effect is acceptable, but the course of treatment is long and the effect is slow, it is easy to produce side effects such as pleural thickening, adhesion, and malabsorption of pleural effusion, and the recurrence rate is high. During t

Method used

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  • Traditional Chinese medicine composition for curing tuberculous exadative pleurisy and preparation method thereof
  • Traditional Chinese medicine composition for curing tuberculous exadative pleurisy and preparation method thereof
  • Traditional Chinese medicine composition for curing tuberculous exadative pleurisy and preparation method thereof

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preparation example Construction

[0084] The present invention also provides a preparation method of the above-mentioned Chinese medicine composition, when the dosage form of the Chinese medicine composition is a tablet, specifically:

[0085] In the first step, mix yam, pearl ginseng, jujube, Mingdangshen, Schisandra chinensis, Polygonatum odoratum and Nansha ginseng, grind them, and add ethanol with an alcohol concentration of 65%~80% until the surface of the raw material medicine added in this step is completely submerged , stirred at a temperature of 30°C~40°C for 2h~3h, cooled to room temperature, placed in a percolator, and added an alcohol concentration of 12~15 times the mass of the raw material drug added in this step to 65 Soak in %~80% ethanol overnight, then percolate at a flow rate of 15ml~18ml per kilogram of medicinal materials per minute, collect 12 times the amount of percolation liquid of medicinal materials, recover ethanol, concentrate to 60°C to an extract with a relative density of 1.2~1.4, ...

Embodiment 1

[0094] The preparation of embodiment 1 granule 1

[0095] Mix 85g of yam, 65g of pearl ginseng, 55g of jujube, 35g of Mingdangshen, 55g of schisandra, 55g of Polygonatum odoratum and 50g of Nansha ginseng, grind them, add ethanol with an alcohol concentration of 75% until the surface of the above-mentioned added raw materials is completely submerged, Stir at a temperature of 40°C for 3 hours, cool to room temperature, place in a percolator, soak in 5.5kg of ethanol with an alcohol concentration of 75% overnight, then percolate at a flow rate of 15ml per minute per kg of medicinal materials, and collect 4.8 kg of percolation liquid, recovered ethanol, concentrated to extract at 60°C with a relative density of 1.2, then added 2 kg of water and stirred evenly, boiled to dissolve, refrigerated overnight, filtered to obtain the filtrate, and then added 4 times the volume of the filtrate The ethyl acetate extraction of 3 times, the combined ethyl acetate extract, concentrating under...

Embodiment 2

[0096] The preparation of embodiment 2 granules 2

[0097] Mix 87g of yam, 67g of pearl ginseng, 57g of jujube, 37g of Mingdangshen, 57g of Schisandra chinensis, 57g of Polygonatum odoratum and 52g of Nansha ginseng, pulverize, add ethanol with an alcohol concentration of 75% until the surface of the raw material drug added above is completely immersed, Stir at a temperature of 40°C for 3 hours, cool to room temperature, place in a percolator, soak in 5.5kg of ethanol with an alcohol concentration of 75% overnight, then percolate at a flow rate of 15ml per minute per kg of medicinal materials, and collect 4.9 kg of percolation liquid, recovered ethanol, concentrated to extract at 60°C with a relative density of 1.4, then added 2 kg of water and stirred evenly, boiled to dissolve, refrigerated overnight, filtered to obtain the filtrate, and then added 4 times the volume of the filtrate The ethyl acetate extraction of 3 times, combined ethyl acetate extract, concentrated under r...

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Abstract

The invention provides a traditional Chinese medicine composition for curing tuberculous exadative pleurisy. The bulk drugs of the traditional Chinese medicine composition include flos farfarae, root bark of white mulberry, Chinese yam, euphorbia kansui, rhizoma panacis majoris, folium eriobotryae, radix stemonae, Chinese-date, inula flower, Chinese mahonia stems, rhizoma zingiberis, rhizoma sparganii, flowers carthami, folia perillae acutae, allium macrostemon, selaginella tamariscina, vine of multiflower knotweed, exocarpium, changium smyrnioides, poria cocos, semen coicis, turmeric, schisandra chinensis, semen lepidii, radix polygonati officinalis, rhizoma anemarrhenae, dayflower, polygonum cuspidatum, adenophora tetraphylla and kaladana. The traditional Chinese medicine composition reduces untoward effect of hydrothorax absorption, shortens course of disease, reduces pleural adhesions, pleural thickening and chest pain, enables hydrothorax absorption of patients to be quick, remarkably alleviates chest pain, and greatly reduces rate of pachynsis pleurae or pleural adhesion, thereby overcoming side effects caused by western drug therapy and having a certain curative effect on curing tuberculous exadative pleurisy.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating tuberculous exudative pleurisy and a preparation method thereof. Background technique [0002] Tuberculosis is still a preventable infectious disease with the highest morbidity and mortality worldwide. Tuberculous exudative pleurisy is the second most common form of extrapulmonary tuberculosis after lymph node tuberculosis. Tuberculous exudative pleurisy is the most common extrapulmonary tuberculosis. Exudative tuberculous exudative pleurisy is more common, and its incidence rate accounts for 54.8% of pleural effusions. [0003] Tuberculous exudative pleurisy is the process of inflammatory pathological changes such as hyperemia, exudation, necrosis, hyperplasia and fibrosis of the pleura after the body is infected with Mycobacterium tuberculosis. The exudative stage is dominated by pleural effusion, wh...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61K9/20A61K9/16A61K9/14A61K9/48A61K9/00A61P31/06
Inventor 不公告发明人
Owner CHONGQING XUANNU BIOTECH
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