Point source irradiating method and tool for chronic irradiation of animals in batch experiments

An experimental animal, chronic technology, applied in animal taming devices, applications, animal husbandry, etc., can solve the problems of limited number of irradiated animals, affecting expression, and difficulty in ensuring the dose rate of animals in different directions, and achieve experimental results. accurate and reasonable effect

Active Publication Date: 2013-05-08
CHINA INST FOR RADIATION PROTECTION
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Problems solved by technology

The head and tail of the irradiated animal are fixed by the fixing clip, and the side of the experimental animal is facing the radiation source. The radiation dose at the central axis of the animal is the whole body dose, and the radiation source is the center of the circle. Guarantee the exposure dose rate of animals in different orientations; and due to the limitation of the fixing clip, the number of exposure animals placed around the radioactive source is limited
Moreover, since metabolomics and stress physical and chemical indicators are closely related to the physiological and mental state of the body, the expression of these indicators will be affected after the activities of the irradiated animals are restricted.

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  • Point source irradiating method and tool for chronic irradiation of animals in batch experiments
  • Point source irradiating method and tool for chronic irradiation of animals in batch experiments

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Embodiment Construction

[0017] The present invention will be described below in conjunction with the accompanying drawings and specific embodiments.

[0018] The invention establishes a point source irradiation method and tool that can be used to ensure that batches of experimental animals can move relatively freely while receiving uniform irradiation at equal dose rates, and provides equal doses for animal irradiation experiments in the study of low-dose radiation biological effects. Rate chronic irradiation provides irradiation methods and tools.

[0019] In order to ensure that the irradiated animals can maintain relatively free movement during the irradiation process, the method of fixing clips should not be used, but cages should be used, and the animal activity space should not be too large to affect the accuracy of the irradiated dose; in order to ensure that the same batch of irradiated animals At the same time, if they are irradiated at the same dose rate, the circular irradiation method wit...

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Abstract

The invention relates to the field of radiation biological effect research of whole body irradiation, in particular to a point source irradiating method and tool for chronic irradiation of animals in batch experiments. Animals are placed in an annular cage and can move relatively free in the cage, simultaneously, a radioactive source is arranged at the center position of the annular cage for irradiating the animals in the cage for regular time, and the animals in different positions of the cage can receive irradiation of equal dosage rate. The point source irradiating method and tool solves the problem demanding prompt solution in chronic low-dosage irradiation experiments and enables experiment results to be accurate and reasonable.

Description

technical field [0001] The invention relates to the field of research on the biological effects of whole-body radiation exposure, in particular to a point source irradiation method and tool for chronically irradiating batches of experimental animals. Background technique [0002] The biological effect of radiation is the biological basis of radiation protection, and its research results have important theoretical significance and application value in the formulation of radiation protection limits and the evaluation of radiation protection effects. In the study of radiation biological effects, radiation damage and biological effects are closely related to the exposure dose of the research object. Carry out related research with experimental animals. [0003] With the development of radiation protection technology, large-dose exposure may occur only in accidents or emergency situations. Under normal circumstances, the radiation exposure received by radiation workers is basica...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01K15/02
Inventor 段志凯郭月凤左雅慧郭俊郭万龙刘建功党旭红
Owner CHINA INST FOR RADIATION PROTECTION
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