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Xenogenic acellular dermal matrix particle soft tissue filling agent and preparation method thereof

A technology of decellularized dermis and fillers, applied in medical science, prostheses, etc., which can solve problems such as usability and lack of preparation methods

Inactive Publication Date: 2013-06-05
潘华倩
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Existing soft tissue fillers are deficient in performance, preparation methods, etc., and need further improvement

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0019] (1) The heterogeneous acellular dermal matrix that has not been cross-linked is freeze-dried and ultrafinely pulverized to prepare particles with a diameter of less than 75 microns;

[0020] (2) The cross-linked heterogeneous acellular dermal matrix is ​​freeze-dried and ultrafinely pulverized to prepare particles with a diameter of less than 75 microns;

[0021] (3) Enzymatically hydrolyzing the heterogeneous acellular dermal matrix without cross-linking treatment into collagen, and preparing medical collagen powder after freeze-drying;

[0022] (4) Mix 1-50% of non-cross-linked heterogeneous acellular dermal matrix particles (weight percentage, example 1%, 25%, 50%), and 1-50% of cross-linked heterogeneous acellular dermal matrix particles (weight percentage, example 1%, 25%, 50%), medical collagen powder 1~50% (weight percentage, example 1%, 25%, 50%) mixed to prepare heterogeneous acellular dermal matrix particle soft tissue filler;

[0023] (5) The heterogeneous a...

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Abstract

The invention discloses a xenogenic acellular dermal matrix particle soft tissue filling agent and a preparation method thereof. The product consists of xenogenic acellular dermal matrix particles which are not treated by a cross-linking treatment, xenogenic acellular dermal matrix particles treated by a cross-linking treatment and medical collagen powder. The filling agent disclosed by the invention is convenient to prepare and excellent in filling agent, and is specifically suitable for filling soft tissue for aesthetic and plastic surgery, such as winkle eliminating and depression filling.

Description

technical field [0001] The invention relates to a soft tissue filler and a preparation method thereof. Background technique [0002] The existing soft tissue fillers have deficiencies in performance, preparation methods, etc., and need to be further improved. Contents of the invention [0003] The purpose of the present invention is to provide a heterogeneous acellular dermal matrix particle soft tissue filler with convenient preparation and good filling effect and a preparation method thereof. [0004] Technical solution of the present invention is: [0005] A heterogeneous acellular dermal matrix microparticle soft tissue filler is characterized in that it is composed of the following components by weight percentage: [0006] Non-cross-linked xenogeneic acellular dermal matrix microparticles 1~50% [0007] Cross-linked heterogeneous acellular dermal matrix particles 1~50% [0008] Medical collagen powder 1~50%; [0009] Among them, medical collagen powder is collage...

Claims

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Application Information

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IPC IPC(8): A61L27/36A61L27/24
Inventor 潘华倩
Owner 潘华倩
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