Externally applied traditional Chinese medicament for treating breast hyperplasia disease

A technology of mammary gland hyperplasia and traditional Chinese medicine, applied in diseases, drug combinations, medical formulas, etc., can solve the problems of long treatment course, high cost, liver and stomach damage, etc., and achieve the effect of less toxic side effects, convenient use, and good curative effect

Inactive Publication Date: 2015-02-04
THE AFFILIATED HOSPITAL OF QINGDAO UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, traditional Chinese medicine mostly uses traditional Chinese medicine decoctions for treatment, which makes it difficult for patients to persist in treatment. Coupled with the emotional impact, the disease is prone to relapse and the curative effect is unstable. Long-te

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0061] Example 1 Traditional Chinese medicine cataplasm

[0062] White peony root 25g, curcuma 35g, pangolin 15g, passepartout 15g, toosendan 20g, sinensis 25g, myrrh 15g, codonopsis 40g, kelp 20g, saponins 25g, cistanche 20g, turmeric 35g, horse ear grass Mix 15g, 20g of bitter scrophulariae, 25g of kudiding, 30g of inula, 15g of celery, 20g of Han Xincao, 25g of Bupleurum, 20g of bergamot and 25g of tangerine peel, add 2.5kg of ethanol with an alcohol concentration of 80%, and heat Extract after 4 hours of reflux, filter the extract, further add 1.5 kg of ethanol with an alcohol concentration of 80% in the obtained filter residue, extract after heating and reflux for 2 hours again, filter the extract, mix the filtrate obtained twice, and carry out Concentrate under reduced pressure until concentrated to an extract with a relative density of 1.29 (70°C), add 0.5 g of aluminum hydroxide into a container containing 40 g of glycerin, and mix thoroughly to obtain a mixture; put 0...

Embodiment 2

[0063] Embodiment 2 Chinese medicine gel

[0064] White peony root 25g, curcuma 35g, pangolin 15g, passepartout 15g, toosendan 20g, sinensis 25g, myrrh 15g, codonopsis 40g, kelp 20g, saponins 25g, cistanche 20g, turmeric 35g, horse ear grass Mix 15g, 20g of bitter scrophulariae, 25g of kudiding, 30g of inula, 15g of celery, 20g of Han Xincao, 25g of Bupleurum, 20g of bergamot and 25g of tangerine peel, add 2.5kg of ethanol with an alcohol concentration of 80%, and heat Extract after 4 hours of reflux, filter the extract, further add 1.5 kg of ethanol with an alcohol concentration of 80% in the obtained filter residue, extract after heating and reflux for 2 hours again, filter the extract, mix the filtrate obtained twice, and carry out Concentrate under reduced pressure and concentrate to an extract with a relative density of 1.29 (70°C). Add 5 g of the weighed excipient carbomer to fully swell with water, add 2 g of preservative methyl paraben, and penetration enhancer lauryl ...

Embodiment 3

[0065] Embodiment 3 clinical data

[0066] normal information

[0067]The 221 patients were all female, and all cases were divided randomly into a treatment group (cataplasm group) and a control group (western medicine oral group). The treatment group included 112 cases, aged 28-49 years, with a course of disease ranging from 2 to 13 years. An average of 6 years and 2 months; the site of the disease, 37 cases of one breast disease, 75 cases of bilateral breast disease. The control group included 109 cases, aged 29 to 50 years, with a disease duration of 2 to 12 years, with an average duration of 6 years and 5 months; 31 cases were affected by one breast, and 78 cases were affected by both breasts.

[0068] Diagnostic criteria: Refer to the eighth meeting of the Breast Disease Professional Committee of the Chinese Society of Surgery of Traditional Chinese Medicine in 2002. ①Symptoms and signs: There are different degrees of swelling, tingling or dull pain in the breast, which...

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PUM

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Abstract

The invention provides an externally applied traditional Chinese medicament for treating the breast hyperplasia disease. The externally applied traditional Chinese medicament comprises the following raw medicinal materials: white paeony root, curcuma zedoary, pangolin, beautiful sweetgum fruit, toosendan fruit, carpet bugle, myrrh, dangshen, laminaria, spina gleditsiae, herba cistanche, radix curcumae, commelina diffusa, picria fel-terrae, bunge corydalis herb, inula japonica, cryptotaenia japonica hassk, scutellaria indica, radix bupleuri, fingered citron and pericarpium citri reticulatae. The externally applied traditional Chinese medicament provided by the invention is used for treating the breast hyperplasia disease by a percutaneous local medicament administration method, and is quick in response, low in toxic and side effect and convenient to use, and has a treatment effect.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to an external Chinese medicine for treating mammary gland hyperplasia. Background technique [0002] Hyperplasia of Mammary Gland (HMG) is a benign proliferative disease of breast tissue. It is neither inflammation nor tumor. It is one of the most common breast diseases in women of childbearing age, accounting for about 40% of women of childbearing age. Accounting for 75% of all breast diseases, the incidence rate is increasing year by year, seriously affecting the physical and mental health of women. [0003] This disease belongs to the category of "breast addiction" in traditional Chinese medicine. The incidence is on the rise at present. The atypical hyperplasia is a precancerous lesion. Therefore, the treatment aims to improve the quality of life of women and prevent breast cancer. Oral administration and surgical treatment are the main methods. However, s...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61K9/06A61K9/70A61P15/14A61K35/36
Inventor 杨硕孙树芹
Owner THE AFFILIATED HOSPITAL OF QINGDAO UNIV
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