A kind of hydrogel wound dressing for treating laser burn and burn and scald and preparation method thereof

Abstract

The invention relates to hydrogel wound dressing for treating laser cauma and burns and scalds. The active components of the hydrogel wound dressing include an antibacterial agent, a humectant and a stabilizer, wherein the antibacterial agent inhibits adhesion and growth of the wound of laser cauma and surrounding bacteria and can kill various pathogenic bacteria at the cauma part, so as to effectively promote union of the laser cauma. The antibacterial agent adopted by the invention does not generate drug resistance, the humectant can maintain moisture of the wound, promote union of the wound surface, prevent formation of scars and alleviate wound pain. With the adoption of the stabilizer, the hydrogel maintains long-time antibacterial effectiveness. Experiments verify that the hydrogel dressing provided by the invention has the effects of effectively relieving wound pain, controlling local infection, maintaining moisture of wound skins, protecting skins, accelerating and promoting union of wound surface and wound and preventing formation of scars, and can be used for healing laser-burned skin wound surfaces (such as laser mole removal and the like) and wound surfaces of burns and scalds.

Description

technical field [0001] The invention belongs to a wound dressing and a preparation method thereof in the technical field of medical materials, in particular to a hydrogel wound dressing for treating laser burns and burns and a preparation method thereof. Background technique [0002] Everyone has some moles on their face or body. A few moles are present at birth but most of them gradually increase after puberty. Moles are mainly caused by the accumulation of melanocytes on the skin. They are brown to black spots or papules, some are flat, some are raised on the skin surface, and some even grow hair. Most of the moles are benign, and only a few of them will become malignant, especially the moles located on the lips, palms and soles. Due to long-term stimulation, they may become malignant and cancerous, so it is advisable to remove them. At present, there are many ways to remove moles, including laser method, electrocautery method, chemical drug or salicylic acid cauterizatio...

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Problems solved by technology

As published on June 13, 2007, "Drug-containing Chitosan Polyvinyl Alcohol Hydrogel Dressing and Its Preparation Method" (CN1320931C) discloses a drug-containing polyvinyl alcohol hydrogel chitosan Dressing, the medical hydrogel dressing can be used to treat various skin wounds and burns, but the dressing has no antibacterial properties, and the dressing cannot be used when the wound is infected or has the possibility of being infected

"A medical dressing containing nano-silver and carboxymethyl chitosan and its preparation method" (CN102114265A) published on July 6, 2011 discloses a medical dressing containing nano-silver and carboxymethyl chitosan, which has Good antibacterial effect, but the preparation process of the medical dressing is too complicated, freeze-drying equipment is required for preparation, and the preparation cost is relatively high. The theory that a moist environment favors wound healing

"Liquid wound dressing with wound healing promotion and antibacterial function" (CN100471528C) published on October 25, 2006 discloses a liquid (gel-like) wound dressing with wound healing promotion and antibacterial function. The liquid dressing mainly Using nano-silver as an antibacterial agent, the preparation process of nano-silver is complicated and cumbersome, and research in recent years has shown that nano-silver can be deposited in the body after being absorbed, which is highly toxic

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