Method for manufacturing microstructure body

A manufacturing method and technology of microstructures, applied in the direction of microstructure technology, microstructure devices, manufacturing microstructure devices, etc., can solve problems such as complexity, drug loss, and insufficient hardness of microneedles, and achieve the effect of minimizing losses

Active Publication Date: 2014-01-08
RAPHAS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

The use of manufacturing methods utilizing molding techniques results in a complex and time-consuming

Method used

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  • Method for manufacturing microstructure body
  • Method for manufacturing microstructure body
  • Method for manufacturing microstructure body

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Embodiment Construction

[0026] Exemplary embodiments of the present invention will be described in detail below with reference to the accompanying drawings. While the invention has been illustrated and described in conjunction with exemplary embodiments thereof, it will be apparent to those skilled in the art that various modifications may be made without departing from the spirit and scope of the invention.

[0027] figure 1 A method of manufacturing a microstructure according to a first exemplary embodiment of the present invention is illustrated; figure 2 Schematically showing a cross-sectional view of a microneedle as a function of stretching speed; and image 3 Dots of different kinds of viscous ingredients are shown.

[0028] First, the present invention relates to a method of manufacturing a microstructure. Here, the microstructure includes microneedles, microsurgical blades, microknives, microfibers, microprojections, microprobes, microbarbs, microarrays, and microelectrodes. In particul...

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Abstract

The present invention relates to a method for manufacturing a microstructure body, which can include a functional substance that is sensitive to heat, can enable sufficient hardness, and can minimize the loss of the functional substance. The method for manufacturing the microstructure body, according to the present invention, comprises the following steps: forming a bottom layer by coating an adhesive substance on a plate-shaped first substrate and then drying; spotting an adhesive composition on a plurality of spots, which are separated away from each other, on the bottom layer; tensioning the adhesive composition by relatively moving a second substrate with regard to the first substrate; solidifying the tensioned adhesive composition; and cutting the solidified adhesive composition.

Description

technical field [0001] The present invention relates to a method of manufacturing microstructures such as microneedles using air blowing technology. Background technique [0002] Although various drugs and phytonutrients have been developed for the treatment of diseases, there are still some aspects that need to be improved during the process of infusion into the human body, such as crossing biological barriers (e.g., skin, oral mucosa, blood-brain barrier, etc.) Delivery and drug delivery efficiency. [0003] Generally, drugs and phytonutrients are taken orally in tablet or capsule form. However, since various drugs are digested or absorbed in the gastrointestinal tract or lost due to the mechanism of the liver, these drugs cannot be efficiently delivered only by such oral administration. In addition, some drugs do not diffuse efficiently across the intestinal mucosa. In addition, patient medication adherence is an issue (for example, patients who need to take their medi...

Claims

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Application Information

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IPC IPC(8): A61M37/00A61M5/158B81C1/00
CPCA61K9/0021A61M37/0015A61M2037/0053A61M2037/0046B81C1/00111
Inventor 丁炯一郑道铉金正东金米洛
Owner RAPHAS
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