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Aquagel composition and application composed of same

A composition and hydrogel technology, applied in the direction of non-active ingredient medical preparations, drug combinations, aerosol delivery, etc., can solve the problem of unstable poultice, unusable poultice for burns, and easy formation of deposits and other problems, to achieve the effect of reducing pain and burning sensation

Active Publication Date: 2014-01-15
SHENG CHUN TANG PHARMA INDAL +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are still many problems in the preparation and use of the above-mentioned dressings. For example, the sodium carboxymethylcellulose needs to exist at a pH of 7-9 or more to be stable, but alkaline dressings are harmful to human skin.
Furthermore, when the sodium carboxymethyl cellulose and gelatin exist simultaneously, it is easy to form a deposit, which causes the dressing to be unstable, and the dressing cannot be used on the damaged part of the burn.

Method used

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  • Aquagel composition and application composed of same
  • Aquagel composition and application composed of same
  • Aquagel composition and application composed of same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1~12

[0046] [Examples 1-12] Hydrogel composition and dressing

[0047] Mix the polyacrylate and glycerol uniformly to form the first component; mix pure water, acid-base regulator and functional reagents uniformly to form the second component; then, evenly mix the first component and the second component , The hydrogel composition can be prepared. The types of raw materials and their usage are shown in Table 1.

[0048] The above-mentioned hydrogel compositions are respectively formed on the substrate, and the patch can be formed after being matured.

[0049] 【Evaluation Items】

[0050] 1. Chilling effect: Place the patches of Examples 1, 2, 8, 9 and 12 in a refrigerator at 4°C for more than 8 hours, and quickly place them on the subject’s hands near the elbows of the forearms, and then heat them with infrared rays. The imager (model: NEC G100W2) is tested, and one frame is taken every 10 seconds, and the test is performed for 15 minutes, with a total of 90 frames and output results.

[0...

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PUM

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Abstract

The invention relates to an aquagel composition and an application composed of the same. The aquagel composition contains 5-10wt% of polyacrylate, 15-41wt% of polyhydric alcohols, 47-76wt% of pure water and 0.01-9wt% of functional reagent, wherein the weight ratio of the pure water to the polyhydric alcohols ranges from 1.1 to 5. When the aquagel composition or the application is applied to the skin of a human body, the temperature of the skin of the human body can be rapidly reduced by over 5 DEG C and can be reduced to be within a temperature range (over 15 DEG C) which can be borne by the skin, and the condition of skin cold injury caused by continuing to reduce the temperature of the skin can be avoided. In addition, when the aquagel composition or the application is applied to a burn / scald wound part, the temperature can be reduced to be within the range which can be borne by the skin, so that the aquagel composition or the application has a remarkable effect on future wound healing.

Description

Technical field [0001] The invention relates to a dressing agent, in particular to a dressing agent of a hydrogel composition. Background technique [0002] The most critical step in dealing with burns and scalds is to cool the damaged part, and refer to the contents of the journal Burn,2000,28,173-176, to understand that it is better to use cold water at 8℃~25℃ and wash the damaged part. The time for the site is about 15-20 minutes, and the ideal temperature is about 15°C, so that it will not cause frostbite of the damaged site, and the problem of difficult healing of the damaged site in the future will occur. At present, there are many products on the market that can lower the body surface temperature, such as ice bags, ice pillows, heat dissipation stickers, etc., which are applied to parts damaged by burns and scalds. These products have the problem of inconvenience to use. A dressing agent that can cool the damaged part during scald treatment. [0003] The formula design of ...

Claims

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Application Information

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IPC IPC(8): A61K9/06A61K47/32A61P17/02
Inventor 郑育修黄雅翌高尉凰郑如惠蔡睿勋王美玲林俊州陈姿吟苏丽华杨濬瑞
Owner SHENG CHUN TANG PHARMA INDAL
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