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Traditional Chinese composition used for treating atopic dermatitis as well as preparation method of composition

A technology of atopic dermatitis and composition, applied in the field of traditional Chinese medicine composition for treating atopic dermatitis and its preparation, capable of solving problems such as poor itching effect, achieving the effects of convenient administration, short healing time, and less recurrence

Inactive Publication Date: 2014-01-22
昌乐县乐器产业发展中心
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The lesions of AD patients are also accompanied by severe itching symptoms. Clinically, the second-generation antihistamines are not effective in treating AD pruritus, while the first-generation sedative antihistamines have a better effect on AD pruritus. Efficacy, suggesting the role of neuroimmune factors in the pathogenesis of AD

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0069] Example 1 Patches

[0070] The embodiment of the present invention provides a traditional Chinese medicine composition for treating atopic dermatitis, the dosage form is a patch, and its preparation method is as follows:

[0071] a. Weigh 1600g Coptis chinensis, 1400g Cortex Phellodendri, 1700g Sophora flavescens, 1400g Burnet, 1300g pomegranate peel, 1400g Kochia, 1600g Astragalus, 1400g Atractylodes macrocephala, 1500g angelica, 1500g Shouwu, 1400g white peony, 1600g Chuanxiong, 1600g Nepeta , Fangfeng 1600g, Uncaria 1400g, Licorice 1600g, Adenophora 1700g, Coix Seed 1600g, Poria 1800g, Habitat 1700g, Radix Paeoniae Rubra 1500g, Digupi 1500g, Langyin 1500g, Tianhuafen 1900g, Scutellaria baicalensis 1600g, Anemarrhena 1700g, Ophiopogon japonicus 1900g, 1500g Dabaoqin, 1600g papaya, 1500g Salvia miltiorrhiza, 1500g Caulis Spatholobus, 1500g Tribulus terrestris, 1600g top ten merits, 1600g Lingxiaohua and 1500g Senecio, add 10 times the amount of 75% ethanol, heat and re...

Embodiment 2

[0076] Example 2 liniment

[0077] The embodiment of the present invention provides a traditional Chinese medicine composition for treating atopic dermatitis, the dosage form is liniment, and its preparation method is as follows:

[0078] The preparation method comprises the following steps:

[0079] a. Take by weighing 1200g of Coptis Rhizoma, 1800g of Phellodendron Cortex Phellodendri, 2200g of Sophora Sophora, 1100g of Burnet, 1600g of Pomegranate Peel and 1800g of Kochia Kochia according to the weight and part ratio, and soak in 60-80% medium ethanol for 2-3 hours, Heating and extracting at a temperature of 60-85° C. for 3 times, each time for 1 hour, to obtain an extract, and the ethanol used is 10 times the total weight of the raw medicinal materials;

[0080] b, heating and concentrating the extract in step a, concentrating to a concentrated solution with a relative density of 1.06, and standing for subsequent use;

[0081] c. Weigh astragalus 1200g, Atractylodes macr...

Embodiment 3

[0084] Example 3 Tablet

[0085] Take 1200g Coptis chinensis, 1200g Cortex Phellodendri, 1200g Sophora flavescens, 1200g Burnet elm, 1000g pomegranate peel, 1000g Kochia scoparia, 1000g astragalus, 1000g Atractylodes macrocephala, 1000g angelica, 1000g Shouwu, 1200g white peony, 1000g Chuanxiong, 1000g Nepeta, 1000g Fangfeng , Uncaria 1000g, Licorice 1000g, Radix Ginseng 1000g, Coix Seed 1200g, Poria Cocos 1000g, Habitat 1200g, Chishao 1000g, Digupi 1000g, Coryne 1700g, Tianhuafen 1200g, Scutellaria baicalensis 1200g, Anemarrhena 1200g, Ophiopogon japonicus 1200g, 1700g celery, 1000g papaya, 1000g salvia miltiorrhiza, 1000g angelica, 1000g Caulis Spatholobus, 1000g Tribulus terrestris, 1000g top ten merits, 1000g Lingxiaohua and 1000g Senecio; put into 10 times the amount of 70% ethanol, heat and reflux to extract twice, For 45 minutes each time, extract the active ingredient, and use the dregs for later use. Combine the 2 extracts and let stand to obtain extract 1; then add 1...

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PUM

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Abstract

The invention discloses a traditional Chinese medicine composition used for treating atopic dermatitis. The traditional Chinese composition comprises the raw materials as follows: coptis chinensis, golden cypress, radix sophorae flavescentis, sanguisorba officinalis, pomegranate bark, fructus kochiae, astragalus membranaceus, white atractylodes rhizome, angelica sinensis, fleece-flower roots, radix paeoniae alba, ligusticum wallichii, schizonepeta, Chinese parsnip roots, uncaria rhynchophylla, liquorice, adenophora stricta, semen coicis, poria cocos, dried rehamnnia roots, roots of common peony, cortex lycii radicis, manyspiny knotweed herb, radix trichosanthis, scutellaria baicalensis, rhizoma anemarrhenae, radix ophiopogonis, dickinsia hydrocotyloides franch, pawpaws, roots of red-rooted salvia, caulis spatholobi, caltrop, Chinese mahonia, campsis grandiflora and senecio scandens. The traditional Chinese composition disclosed by the invention has effects of nourishing yin and clearing heat, and nourishing blood and moisturizing skin, and is positive in treatment effect of treating atopic dermatitis by applying a method of nourishing yin and clearing heat. Moreover, the traditional Chinese composition is simple in preparation process, slight in toxic and side effect and convenient to dose, and the preparation is easy to prepare a novel drug which is low in cost. Besides, the traditional Chinese composition disclosed by the invention can directly reach the focus of infection, is short in curing time and not easy to have a relapse after healing.

Description

[0001] technical field [0002] The invention relates to a medical preparation containing raw materials derived from plants, animals or minerals, in particular to a traditional Chinese medicine composition for treating atopic dermatitis and a preparation method thereof. [0003] Background technique [0004] Atopic dermatitis (AD) is a chronic, relapsing inflammatory skin disease, mainly manifested by severe itching, obvious eczema-like changes and dry skin. AD often starts in infants and young children, and some patients continue for life. It can seriously affect the quality of life of patients due to chronic recurrent eczematous rash, severe itching, sleep loss, dietary restrictions, and psychosocial effects. After the Second World War, the incidence of AD increased. The incidence of AD in Western developed countries was as high as 10%-20% in children, and about 1%-3% in adults. Some patients may develop concurrent allergic asthma, allergic Rhinitis and other allergy-rel...

Claims

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Application Information

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IPC IPC(8): A61K36/8994A61K9/20A61K9/28A61K9/30A61K9/48A61K9/08A61K9/16A61K9/14A61K9/02A61K9/06A61P17/00
Inventor 李佃场梁轶聪
Owner 昌乐县乐器产业发展中心
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