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A kind of preparation method of Polygonum cephalosa hypoglycemic extract tablet

A technology of Polygonum cephalum and hypoglycemia, which can be applied to medical preparations containing active ingredients, pill delivery, drug combination, etc., and can solve the problem of a small amount of clinical drugs

Active Publication Date: 2015-08-19
浙江佐力百草中药饮片有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most of the research on it is aimed at anti-inflammatory activity, and the number of clinical drugs is small
In addition, the efficacy of GCP in the treatment of diabetes has not been reported

Method used

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  • A kind of preparation method of Polygonum cephalosa hypoglycemic extract tablet
  • A kind of preparation method of Polygonum cephalosa hypoglycemic extract tablet
  • A kind of preparation method of Polygonum cephalosa hypoglycemic extract tablet

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Example 1: Preparation of Polygonum cephalica Hypoglycemic Extract Tablets

[0019] 1) Add 24 times the amount of 60% ethanol to the dried Polygonum cephalum, soak for 30 minutes, extract 3 times, 1.5 hours each time, combine the extracts, filter and concentrate to the equivalent amount of medicinal materials 1g / ml, and obtain the alcohol extraction concentrate ;After alcohol extraction, the dregs are decocted in water twice, adding 12 times the amount of water for the first time, extracting for 1.5 hours, adding 10 times the amount of water for the second time, extracting for 1 hour, combining the two decoctions, filtering and concentrating to the equivalent medicinal material Amount of 1g / ml, to obtain a water-extracted concentrated solution, combine the alcohol-extracted concentrated solution and the water-extracted concentrated solution, then concentrate to an equivalent medicinal material amount of 1g / ml, dry, pulverize, and obtain Polygonum cephalum extract powder;...

Embodiment 2

[0023] Example 2: Preparation of Polygonum cephalica Hypoglycemic Extract Tablets

[0024] 1) Add 22 times the amount of 65% ethanol to the dried Polygonum cephalum, soak for 20 minutes, extract 3 times, 1 hour each time, combine the extracts, filter and concentrate to the equivalent amount of medicinal materials 0.8g / ml, and obtain alcohol extraction and concentration liquid; after alcohol extraction, the dregs were decocted twice, adding 10 times the amount of water for the first time, extracting for 1 hour, adding 8 times the amount of water for the second time, extracting for 0.5 hours, combining the two decoctions, filtering and concentrating to an equivalent The amount of medicinal material is 0.8g / ml, and the water extraction concentrate is obtained, and the alcohol extraction concentrated solution and the water extraction concentrated solution are combined, and then concentrated to an equivalent medicinal material amount of 0.8g / ml, dried, and pulverized to obtain Polyg...

Embodiment 3

[0028] Example 3: Preparation of Polygonum cephalosporin hypoglycemic extract tablet

[0029] 1) Add 26 times the amount of 55% ethanol to the dried Polygonum cephalum, soak for 40 minutes, extract 3 times, 2 hours each time, combine the extracts, filter and concentrate to the equivalent medicinal material amount of 1.2g / ml, and obtain alcohol extraction and concentration liquid; after alcohol extraction, the dregs were decocted in water twice, adding 14 times the amount of water for the first time, extracting for 2 hours, adding 12 times the amount of water for the second time, extracting for 0.8 hours, combining the two decoctions, filtering and concentrating to an equivalent The amount of medicinal material is 1.2g / ml, and the water extraction concentrate is obtained, and the alcohol extraction concentrated solution and the water extraction concentrated solution are combined, and then concentrated to a corresponding medicinal material amount of 1.2g / ml, dried, and pulverized...

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Abstract

The invention discloses a preparation method of a polygonum capitatum sugar reduction extract tablet, and belongs to the technical field of Chinese medicine preparations. The preparation method comprises the following steps: 1) preparing polygonum capitatum extract powder; 2) allocating materials; 3) pelletizing and regulating pellets; 4) pressing into tablets. The preparation method of the polygonum capitatum sugar reduction extract tablet is reasonable in design, a mixture liquid which is obtained by performing alcohol extraction and water extraction on polygonum capitatum is prepared into tablets through reasonable parameters and step control, patients can take the tablets conveniently, the tablets can be easily absorbed, and the sugar reduction function of a polygonum capitatum medicine material is remarkably improved.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparations, and in particular relates to a preparation method of a tablet of Polygonum cephalosporin hypoglycemic extract. Background technique [0002] With the improvement of human living standards, changes in lifestyles, and the aggravation of environmental pollution, the incidence of diabetes is increasing year by year. Although Western medicine is highly targeted in treating diabetes and has a significant hypoglycemic effect, there are side effects and uncontrollable insulin use in Western medicine. question. In recent years, screening natural active ingredients from traditional medicines and herbal medicines is a new approach. [0003] GCP (Polygonum cephalosporin) was originally a folk herbal medicine and a traditional Miao medicine. The main effects are clearing away heat, diuresis, treating stranguria and stopping dysentery. Indications of cystitis, pyelonephriti...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/704A61K9/20A61P3/10
Inventor 陈欢陈照荣黄绳武
Owner 浙江佐力百草中药饮片有限公司