Tranexamic acid skin externally applied nano-preparation, as well as preparation method and use thereof

A tranexamic acid and nano-formulation technology, applied in skin diseases, peptide/protein components, emulsion delivery, etc., can solve the problems of poor skin penetration ability of aqueous solution, skin irritation, unclear mechanism, etc., to improve local skin. Dullness, treatment of hyperpigmentation, increased efficacy
CN103565743AInactive Publication Date: 2014-02-12CENT HOSPITAL XUHUI DISTRICT SHANGHAI CITY +1
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
CENT HOSPITAL XUHUI DISTRICT SHANGHAI CITY
Publication Date
2014-02-12
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to a tranexamic acid skin externally applied nano-preparation, as well as a preparation method and a use thereof. The nano-preparation is prepared from tranexamic acid, medicated oil, an emulsifier, pharmaceutical additives, a thickener and pure water. The tranexamic acid skin externally applied nano-preparation provided by the invention has good physiological skin compatibility and can effectively promote the percutaneous absorption of tranexamic acid, improve the effect of preventing or treating pigmentation of the tranexamic acid and avoid toxicity and side effects, which are caused by systemic administration of the tranexamic acid.
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Description

technical field

[0001] The invention belongs to the field of chemical pharmacy, and more specifically relates to a nano-preparation of tranexamic acid for external use on the skin, a preparation method and application thereof. The nano-preparation of tranexamic acid for external use of the present invention has good skin physiological compatibility, can effectively promote the percutaneous absorption of tranexamic acid, improve the effect of tranexamic acid in preventing or treating pigmentation, and avoid the effects of tranexamic acid Toxic side effects caused by systemic medication. Background technique

[0002] Tranexamic acid is also called tranexamic acid, tranexamic acid, the chemical name is trans-4-(aminomethyl)cyclohexanecarboxylic acid, molecular formula: C 8 h 15 NO 2 , molecular weight: 157.21, has the following chemical structure:

[0003]

[0004] Tranexamic acid is an antifibrinolytic hemostatic drug. Since tranexamic acid is similar in structure to t...

Claims

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