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Coffee-flavored metronidazole chewing gum

A technology for chewing gum and metronidazole, which is applied in the field of chewing gum formulation, can solve the problems of short duration, irritation, and weak effect of removing oral odor, and achieves the effect of reducing breath value, being easy to accept, and improving the effect of removing oral odor.

Inactive Publication Date: 2014-02-19
THE FIRST AFFILIATED HOSPITAL HENGYANG MEDICAL SCHOOL UNIV OF SOUTH CHINA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Its matrix is ​​natural gum or glycerin resin, which is non-toxic and non-irritating to the human body, and has good biocompatibility. Remove food residue on the surface of the teeth, stimulate saliva secretion, and rinse the oral cavity surface, which has a certain effect of cleaning the oral cavity, but it cannot fundamentally eliminate the cause of bad breath, so its effect of removing oral odor is weak and lasts for a short time

Method used

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  • Coffee-flavored metronidazole chewing gum
  • Coffee-flavored metronidazole chewing gum
  • Coffee-flavored metronidazole chewing gum

Examples

Experimental program
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Embodiment Construction

[0017] The amounts of components in each of the following formulations are parts by weight.

[0018] 1. Effect of high and low xylitol content on the bitter taste of metronidazole

[0019] Formula 1 (50% high xylitol content, excluding menthol and cocoa powder): 21 parts of synthetic gum base; 25 parts of xylitol; 0.5 parts of metronidazole; 1.5 parts of maltodextrin; 1 part of glycerin; soybean lecithin 0.1 part; 0.5 part of spearmint essential oil; 0.2 part of titanium dioxide; 0.2 part of carnauba wax.

[0020] Formula 2 (low xylitol content of 40%, without menthol and cocoa powder): 26 parts of synthetic gum base; 20 parts of xylitol; 0.5 parts of metronidazole; 1.5 parts of maltodextrin; 1 part of glycerin; soybean lecithin 0.1 part; 0.5 part of spearmint essential oil; 0.2 part of titanium dioxide; 0.2 part of carnauba wax.

[0021] According to the chewing gum production flow process, the sliced ​​metronidazole chewing gum is produced, and each piece of chewing gum co...

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Abstract

The invention relates to a chewing gum capable of removing bad breath. The chewing gum is characterized by comprising the following components in parts by weight: 18 parts of synthetic gum base, 25 parts of xylitol, 3 parts of cocoa powder, 0.5 part of metronidazole, 1.5 parts of maltodextrin, 1 part of glycerol, 0.1 part of soybean phospholipid, 0.5 part of spearmint essential oil, 0.2 part of titanium dioxide and 0.2 part of carnauba wax. The chewing gum is a coffee-flavored metronidazole chewing gum. The bad breath removing effect of the coffee-flavored metronidazole chewing gum lasts for 4 to 8 hours, but the bad breath removing effect of the common chewing gum does not exceed 1 hour. The coffee-flavored metronidazole chewing gum also can be applied to oral care of critical patients. The metronidazole is used for killing odor producing bacteria of an oral cavity, so that the bad breath value is reduced; the oral cavity is cleaned by chewing the chewing gum; the bad odor of the oral cavity is covered by the perfume ingredient of the chewing gum. The chewing gum is organic combination of mechanical therapy and chemical therapy, achieves a synergistic effect of removing bad breath and obviously improves the effect of removing bad breath. The screened formula of the chewing gum can obviously cover the bitter taste of the metronidazole, so people can easily accept the chewing gum.

Description

technical field [0001] The invention relates to a formula of chewing gum for eliminating bad breath in the mouth. Background technique [0002] Halitosis is commonly called as bad breath, which refers to the unpleasant smell emitted from the oral cavity, which seriously affects people's social interaction and mental health. It is estimated that about 10% to 65% of people in the world once suffered from halitosis. The incidence rate of men is significantly higher than that of women. A recent survey shows that the incidence of bad breath in the Chinese population has reached 27.5%, and in Japan and North America it is 25% and 50% respectively. Halitosis has been reported as a disease by WHO, but halitosis has not been classified as an oral disease in modern stomatology, so the preparations for treating halitosis on the market are extremely scarce. With the development of society and economy, people's living standards continue to improve, social interaction activities gradual...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23G4/12A61K31/4164A61K9/68A61K47/26A61K47/10A61K47/22A61L15/44A61P1/02A61P31/02
Inventor 阳波
Owner THE FIRST AFFILIATED HOSPITAL HENGYANG MEDICAL SCHOOL UNIV OF SOUTH CHINA
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