Measuring method and measuring platform for biomechanical performance parameters of in vitro corneas

Abstract

The invention relates to a measuring method and a measuring platform for biomechanical performance parameters of in vitro corneas. The measuring method comprises the following steps: 1, fixing a cornea sample and spraying powder; 2, continuously exerting pressure to deform the cornea sample and recording a pressure value; 3, recording the variations of intervals of powder particles; 4, computing the three-dimensional deformation in each area of the surface of the cornea sample; 5, computing the biomechanical performance parameters through a general constitutive equation. The measuring platform comprises a mounting platform, wherein a cornea fixing device is mounted on the mounting platform and provided with an inner chamber; a clamping end for clamping the cornea sample is arranged at one end of the inner chamber; the other end of the inner chamber is connected with a pressure unit; shooting equipment is arranged at the front end of the cornea fixing device; the pressure unit is connected with a pressure sensor; pressure on the cornea sample is monitored by the pressure unit and the pressure sensor, and deformation of the cornea sample is recorded by the shooting equipment, so that the measurement of regional differences of constitutive parameters of corneas is realized so as to provide references for diagnosis and treatment of related cornea diseases.

Description

technical field [0001] The invention relates to a measurement method and a measurement platform for isolated corneal biomechanical performance parameters, in particular to a measurement method and a measurement platform for corneal biomechanical performance that can measure regional differences in corneal constitutive parameters. Background technique [0002] Keratoconus is a relatively common ophthalmic disease in clinical practice, which can produce highly irregular myopic astigmatism and different degrees of visual impairment. The incidence rate in European and American countries is 0.01%~0.05%, and in Japan is 0.07%~0.08%, but there is still no epidemic in my country. learning information. As an important biological attribute, the biomechanical properties of the cornea can directly affect the shape of the cornea, and then affect the refractive state and optical imaging quality of the cornea. Studies have shown that the occurrence and development of keratoconus are closel...

AI Technical Summary

Problems solved by technology

[0003] In order to solve the problem that the existing corneal biomechanical performance measurement platform cannot measure the regional difference distribution of corneal biomechanical performance, the present invention provides a measurement method and measurement platform for isolated corneal biomechanical performance, which can measure the regional difference of corneal constitutive parameters, Provide reference for the diagnosis and treatment of related corneal diseases

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