Novel blood-clotting thrombolysis full-function detection device

A detection device and full-featured technology, applied in the field of biomedical detection instruments, can solve the problems of poor stability, high price, and inaccurate detection results, and achieve the effects of small and compact device, enhanced stability, and reduced cost.

Active Publication Date: 2014-03-26
SUZHOU INST OF BIOMEDICAL ENG & TECH CHINESE ACADEMY OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] At present, the commercial coagulation and thrombolysis function testing market is mainly monopolized by two imported instruments, TEG and ROTEM, and the supporting reagents used are mainly from abroad, so the price is relatively expensive
At the same time, the detection of thrombus elasticity by these instruments is based on spring hairsprings, which measure the one-dimensional torsional resistance of the blood sample to the probe, which ca

Method used

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  • Novel blood-clotting thrombolysis full-function detection device

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Effect test

Embodiment 1

[0020] A solid microelectromechanical chip is electrically connected to the lower end of the printed circuit board of the coagulation and thrombolysis full-function detection device; the solid microelectromechanical chip includes a rectangular main board and a strip-shaped silicon probe, and the solid microelectromechanical chip is It is cut from a complete silicon wafer; only one set of drive capacitors is etched on the motherboard, and the drive capacitors are comb-shaped drive capacitors, which are located in the middle of the motherboard. Chips with this structure resolve forces and moments in one dimension.

Embodiment 2

[0022] A solid microelectromechanical chip is electrically connected to the lower end of the printed circuit board of the coagulation and thrombolysis full-function detection device; the solid microelectromechanical chip includes a rectangular main board and a strip-shaped silicon probe, and the solid microelectromechanical chip is It is cut from a complete silicon wafer; 3 sets of drive capacitors are etched on the main board, and the 3 sets of drive capacitors are all comb-shaped drive capacitors, of which 1 set of comb-shaped drive capacitors is located in the middle of the motherboard, and the other 2 sets of comb-shaped drive capacitors respectively arranged in parallel at the upper and lower ends of the main board. The chip of this structure can analyze the forces and moments in the two-dimensional x and y directions.

Embodiment 3

[0024] A solid microelectromechanical chip is electrically connected to the lower end of the printed circuit board of the coagulation and thrombolysis full-function detection device; the solid microelectromechanical chip includes a rectangular main board and a strip-shaped silicon probe, and the solid microelectromechanical chip is It is cut from a complete silicon wafer; 5 sets of drive capacitors are etched on the main board, one of which is a comb-shaped drive capacitor; the comb-shaped drive capacitor is located in the middle of the main board, and the other 4 sets of drive capacitors are located in the four corner. The chip of this structure can analyze the forces and moments in the two-dimensional x and z directions.

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Abstract

The invention discloses a novel blood-clotting thrombolysis full-function detection device, a solid microelectronic mechanical chip is electrically connected with the lower end of a printed circuit board, the solid microelectronic mechanical chip comprises a rectangular main board and a long striped silicon probe which are formed by cutting a complete silicon wafer, the main board is etched with 1 ~ 7 groups of driving capacitors, the driving capacitors at least contain 1 group of comb driving capacitors, each group of the comb driving capacitors comprises 2 comb driving capacitors arranged side by side, and each group of the driving capacitors is respectively connected with a capacitance read chip. According to the device, a micro torsion meter of the solid microelectronic mechanical chip is used for replace purely-mechanical testing of an original spring hairspring, the instrument stability is enhanced, the precision of obtained force/torque is improved, the whole device is small and compact, at the same time, the current situation that domestic blood-clotting thrombolysis detection is dependent on import for a long term can be changed, and the blood-clotting thrombolysis full-function detection cost is reduced.

Description

technical field [0001] The invention relates to a biomedical detection instrument, in particular to a novel device for detecting blood coagulation and thrombolysis functions. Background technique [0002] The blood coagulation and thrombolysis function detection device first appeared in 1948. It uses a spring spring as the core to detect the clot elasticity generated during the coagulation and thrombolysis process. It is reflected on the plotter and draws a curve of the thrombus elasticity changing with time. Since this curve can provide the most complete coagulation and thrombolysis parameters in the whole process, the coagulation and thrombolysis function detection device has important research significance for clinical medicine, pathology research and new drug development. [0003] At present, the commercial coagulation and thrombolysis function testing market is mainly monopolized by two imported instruments, TEG and ROTEM, and the supporting reagents used are mainly fro...

Claims

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Application Information

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IPC IPC(8): G01N27/22G01L9/12
Inventor 胡军殷建陈名利林颖白鹏利尹焕才孙海旋
Owner SUZHOU INST OF BIOMEDICAL ENG & TECH CHINESE ACADEMY OF SCI
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