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Lipid-lowering Chinese medicinal composition and preparation method thereof

A technology of a composition and traditional Chinese medicine, applied in the field of medicine and health, can solve the problems of high cost, lack of radical cure, etc., and achieve the effect of rational and scientific prescription

Inactive Publication Date: 2014-04-23
GUANGXI WUZHOU PHARMA GRP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The control of hyperlipidemia needs a long time to carry out, and used expense is expensive, and the Western medicine used clinically at present mainly treats the various diseases that hyperlipidemia causes, diseases such as atherosclerosis, coronary heart disease, pancreatitis, can only Superficially control the expression, but not achieve the purpose of radical treatment. In addition, most western medicines have certain liver and kidney toxicity.

Method used

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  • Lipid-lowering Chinese medicinal composition and preparation method thereof
  • Lipid-lowering Chinese medicinal composition and preparation method thereof
  • Lipid-lowering Chinese medicinal composition and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0062] Embodiment 1 syrup

[0063] Take ginseng diol glycosides 10g, Poria cocos 45g, Alisma 45g, Shouwu 30g, hawthorn 30g, cassia seed 20g, gallinaceae 20g, malt 20g, atractylodes 20g, and cassia twig 20g. Add water to extract all the above-mentioned medicinal materials twice, the amount of water added twice is 10 times and 8 times of the total weight of the medicinal materials respectively, the extraction time of the two times is 2 hours and 1 hour respectively, the extracts are combined, filtered, and the filtrate is concentrated into a flow leaching paste. The syrup preparation is prepared by adding syrup auxiliary materials sucrose, honey, potassium sorbate and water into the extract and stirring evenly.

Embodiment 2

[0064] Example 2 tablet

[0065] Take ginsengdiol glycosides 8g, Poria cocos 40g, Alisma 40g, Shouwu 25g, hawthorn 25g, cassia seed 15g, gallinaceae 15g, malt 15g, atractylodes 15g, and cassia twig 15g. All the above-mentioned medicinal materials were reflux extracted with 40% ethanol for 3 times, the amount of ethanol each time was 10 times, 8 times, and 4 times the total amount of medicinal materials, and the extraction time was 3 hours, 2 hours, and 1 hour respectively, and the extracts were combined and filtered. After the filtrate is concentrated into a liquid extract, it is dried into a dry paste powder, and the auxiliary materials starch, ethanol, and talcum powder are added to obtain a tablet.

Embodiment 3

[0066] Embodiment 3 mixture

[0067] Take ginsengdiol glycosides 12g, Poria cocos 50g, Alisma 50g, Shouwu 35g, hawthorn 35g, cassia seed 25g, gallinaceae 25g, malt 25g, atractylodes 25g, and cassia twig 25g. Add water to extract all the above-mentioned medicinal materials for 3 times, the amount of water added three times is equivalent to 12 times, 8 times, and 6 times of the total weight of the medicinal materials, and the extraction time is 3 hours, 2 hours, and 1 hour respectively, and the extracts are combined and filtered. When the filtrate is concentrated to a clear paste with a relative density of 1.20 at 70°C, add ethanol to make the alcohol content 40%, let it stand for 24 hours, filter, concentrate the filtrate into a liquid extract, add purified water until the total weight is the total weight of medicinal materials 3 times, filling, to get the mixture of the present invention.

[0068] Add mixture auxiliary materials sucrose, ethyl ester, water and potassium sorba...

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Abstract

The invention discloses a lipid-lowering Chinese medicinal composition and a preparation method thereof. The composition is prepared from the medicinal materials of panaxadiol saponins, Indian buead, oriental waterplantain rhizome, multiflower knotweed tuber, hawthorn, cassia seed, chicken gizzard membrane, malt, Chinese atractylodes, cassia twig and the like serving as raw materials. The invention further provides a preparation method of the lipid-lowering Chinese medicinal composition. By using the composition provided by the invention, the levels (P is less than 0.05) of total cholesterol and triglyceride in mouse and rat serums can be lowered remarkably, and an extremely remarkable lipid-lowering effect is achieved.

Description

technical field [0001] The invention relates to the field of medicine and hygiene, in particular to a lipid-lowering traditional Chinese medicine composition and a preparation method thereof. Background technique [0002] Due to abnormal fat metabolism or operation, one or more lipids in plasma are higher than normal, which is called hyperlipidemia, and hyperlipidemia seriously endangers human health. Hyperlipidemia can be divided into two types: primary and secondary. Primary is congenital and hereditary, and is caused by abnormalities in receptors, enzymes, or apolipoproteins involved in lipoprotein transport and metabolism due to single or polygenic defects, or due to environmental factors (diet, nutrition, drugs) ) and by unknown mechanisms. Secondary mostly occurs in metabolic disorders (diabetes, hypertension, myxedema, hypothyroidism, obesity, liver and kidney disease, adrenal hyperfunction), or in combination with other factors such as age, gender, season, drinking...

Claims

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Application Information

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IPC IPC(8): A61K36/8998A61P3/06A61K35/37A61K31/704A61K35/57
Inventor 张栩颜林艳英郑志远刘冠萍吴赛春贤明华卢敏玲
Owner GUANGXI WUZHOU PHARMA GRP
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