HPTLC (high performance thin layer chromatography) quality evaluation method of Xinfeng capsule by adopting coix seeds as reference

Abstract

The invention relates to the field of supervising quality information of traditional Chinese medicine preparation and evaluating the product quality, in particular to an HPTLC (high performance thin layer chromatography) quality evaluation method of a Xinfeng capsule by adopting coix seeds as a reference. The method comprises the following steps of firstly establishing an HPTLC common model by adopting the coix seeds as the reference, and then analyzing the similarity. The method comprises the following steps of (1) preparing a sample solution; (2) preparing a reference medicine solution; (3) determining the HPTLC common model; (4) calibrating a HPTLC common fingerprint peak and establishing a common mode; and (5) analyzing the similarity of the HPTLC common model of the Xinfeng capsule. The experimental scheme is simple to operate, the chromatographic spot is clear, the separation effect is good, the precision and repeatability are good, comprehensive information can be provided for the quality evaluation of Xinfeng capsule by establishing the HPTLC common model adopting the coix seeds as the reference, and a reference is also provided for the fundamental research of the active substance of Xinfeng capsule and the development of new drugs.

Description

technical field [0001] The invention relates to the field of quality information monitoring of traditional Chinese medicine preparations and product quality evaluation, in particular to an HPTLC detection method for Xinfeng capsules with coix seed as a reference. Background technique [0002] The incidence of rheumatoid diseases in my country is increasing year by year, and the disability rate of such diseases is high. Early and reasonable treatment is very important to control the disease. Common rheumatoid diseases include rheumatoid arthritis and ankylosing spondylitis. Rheumatoid arthritis (RA) is a systemic autoimmune disease mainly characterized by non-infectious inflammation of joints and periarticular tissues. And the invasion of bone tissue, leading to the destruction of joint structure. Eventually joint deformity, dysfunction or loss, even disability, loss of life ability. The disease has a high disability rate and has become one of the world-recognized refracto...

AI Technical Summary

Problems solved by technology

[0004] Since the preparation involves many types of medicinal materials and relatively complex chemical components, each medicinal material is easily affected by factors such as place of origin, medicinal part, harvest time, extraction process, etc., which brings great challenges to the effective control and evaluation of the quality of the preparation. certain difficulty

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