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Medicine composition with collagen and water-soluble pearl powder as well as preparation, preparation method and application of medicine composition

A collagen and fish collagen technology, applied in the field of compositions containing collagen and water-soluble pearl powder, can solve the problems of large fluctuation of therapeutic effect, poor user compliance, lack of correlation data, etc., so as to improve body SOD. Activity, inhibit the increase of lipid peroxidation, enhance the effect of blood circulation

Inactive Publication Date: 2014-09-17
ZHEJIANG HAILISHENG BIOTECH +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But the shortcoming of the composition in this document is: the prescription is too complicated, has adopted more traditional Chinese medicine ingredients, and preparation is inconvenient to use, so user's compliance is poor, and the therapeutic effect fluctuates greatly
At the same time, there is a lack of data on the correlation between the combination ratio of the composition and the effect of treating chloasma
[0006] At present, there is no public report of a composition for treating chloasma that does not contain traditional Chinese medicine ingredients and whose active ingredients are only composed of collagen, pearl powder, vitamin C, and vitamin E.

Method used

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  • Medicine composition with collagen and water-soluble pearl powder as well as preparation, preparation method and application of medicine composition
  • Medicine composition with collagen and water-soluble pearl powder as well as preparation, preparation method and application of medicine composition
  • Medicine composition with collagen and water-soluble pearl powder as well as preparation, preparation method and application of medicine composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-7

[0069] Embodiment 1-7 contains collagen protein, water-soluble pearl powder, vitamin C, vitamin E as the preparation of main active ingredient particle

[0070] See Table 1 for the composition of collagen water-soluble pearl powder vitamin C and vitamin E particles in Examples 1-7.

[0071] Table 1

[0072]

[0073] The preparation method of collagen water-soluble pearl powder vitamin C vitamin E particle in embodiment 1-7, comprises the following steps:

[0074] Step 1: Weigh the lactose, mannitol and 50% of the formula amount of fish collagen, marked as Ⅰ;

[0075] Step 2: take an appropriate amount of citric acid (the quality is greater than the formula quantity), pulverize it with a homogenizer or a pulverizer, pass through an 80-mesh sieve, weigh the citric acid after the formula quantity has been sieved, and mark it as II;

[0076] Step 3: Mix Ⅰ and Ⅱ in equal increments to form a mixed powder 1;

[0077] Step 4: Weigh the water-soluble pearl powder of the formula ...

Embodiment 8

[0087] Example 8 Collagen water-soluble pearl powder vitamin C and vitamin E composition related index detection of the present invention

[0088] Through the human food test, according to the Ministry of Health "Health Food Inspection and Evaluation Technical Specifications" (2003 Edition), the collagen water-soluble pearl powder vitamin C and vitamin E composition has been tested for the function of removing chloasma. The relevant information and results of the experiment are as follows:

[0089] 1. Materials and methods

[0090] (1) Sample

[0091] Composition No. 1 of the present invention (the composition of Example 5), No. 2 (1480g of lactose, 416g of mannitol, 40g of citric acid, 16.38g of povidone K30, 18g of steviol glycoside, 35g of milk essence), both of which are packaged , Appearance, color and taste are exactly the same. One of them is the composition of the present invention, the other is a placebo, and the recommended intake is 4.0g / day.

[0092] (2) Select...

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PUM

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Abstract

The invention provides a medicine composition which is used for treating chloasma and contains collagen and water-soluble pearl powder as well as a preparation, a preparation method and an application of the medicine composition. The composition comprises fish collagen, water-soluble pearl powder, vitamin C, vitamin E and main active components. The collagen is high in permeability for skin, can be combined with skin epithelial cells through cuticle, can join in metabolism for improving skin cells and achieves the purpose of moistening skin; the water-soluble pearl powder contains various active component and has important functions of improving the elasticity and the permeability of blood vessels, improving the blood oxygen supply capability, prompting subcutaneous tissue circulation, accelerating metabolism of skin and decomposing stain; as strong antioxidants, vitamin C and vitamin E can prevent accumulation of lipid peroxide, can further inhibit oxidation of dopa and prevent formation of melanin.

Description

technical field [0001] The invention relates to the technical field of medical products, in particular to a composition, a preparation, a preparation method and an application comprising collagen and water-soluble pearl powder. Background technique [0002] Chloasma is a common pigmented skin disease that occurs on the face. Its main manifestations are localized light brown or brown patches on the face, with clear boundary, smooth surface, symmetrical distribution, and butterfly shape. Spread to forehead, lips, etc. Symptoms can be aggravated after exposure to the sun, both men and women, especially middle-aged women, especially during menstruation and pregnancy. It brings many troubles and pains in life and spirit to patients. [0003] The pathogenesis of chloasma is complicated, and the real cause of the disease is still not very clear. At present, it is believed that one of the pathological mechanisms of melasma is the active melanin formation of melanocytes, and vario...

Claims

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Application Information

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IPC IPC(8): A61K38/39A61K9/16A61P17/00A61K35/56A61K31/375A61K31/355
Inventor 夏志国郑杭生袁军岳郑海辉钟江燕顾斌洲
Owner ZHEJIANG HAILISHENG BIOTECH
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