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Sample detection apparatus and sample detection method

A sample detection and position detection technology, which is applied in the medical field, can solve the problems of complex photoelectric detection module structure, lower device reliability, complex timing, etc., and achieve the effect of simple device structure and control timing, compensation drift, and guaranteed accuracy

Active Publication Date: 2014-10-22
SHENZHEN MINDRAY BIO MEDICAL ELECTRONICS CO LTD
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, the structure of the improved photoelectric detection module in the prior art for pre-light detection calibration is more complex, and the entire detection process not only needs to control the operation of the reaction disk, but also needs to control the shutter structure on the photoelectric detection module, and the timing is more complicated. reduces the reliability of the device

Method used

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  • Sample detection apparatus and sample detection method
  • Sample detection apparatus and sample detection method
  • Sample detection apparatus and sample detection method

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Experimental program
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Embodiment 1

[0021] Please refer to figure 1 , the application provides a chemiluminescent immunoassay device, the device mainly includes: a reaction plate 1, a shielding and sealing structure, a photoelectric detection module 3, a reaction container supply unit 4, a reagent plate 2, and sample dispensing stations located at different dispensing stations. Unit 502, reagent dispensing unit 504, mixing unit 7, cleaning and separating unit 6, luminescent liquid tray, luminescent liquid dispensing unit, transport mechanism and control unit. Wherein, the reaction disc 1 is provided with a detection position and a calibration position. The control unit is a host independent of the reaction disk 1, and it is provided with software for timing control. The transport mechanism includes a first transport unit 506 and a second transport unit 500 . figure 1 Each dotted line in shows the motion trajectory of the corresponding unit.

[0022] The reaction disk 1 is used to carry the reaction container ...

Embodiment 2

[0035] Please refer to Figure 5 The difference between the present embodiment and the first embodiment mainly lies in that the calibration position of the reaction disk 1 is not provided with an isolation layer, but is a space between two adjacent detection positions on the reaction disk 1 . Because the reaction disk 1 is hermetically accommodated in a shielding and sealing structure, the shielding and sealing structure can play the role of light protection and heat preservation, so the calibration position itself is in a dark environment when no isolation layer is provided. In this way, in the sample detection method, it is only necessary to control the reaction disk 1 to rotate half a standard interval (half of the interval between 1# and 2#) to alternately realize calibration and light detection.

Embodiment 3

[0037] Please refer to Image 6 The difference between the present embodiment and the first embodiment mainly lies in that several detection positions are set on the reaction plate 1, and only one permanent empty position N# not used to carry the reaction vessel is set as the calibration position. In this way, in the sample detection method, it is only necessary to control the reaction disk 1 to rotate to N# for calibration each time, and then rotate to the detection position for light detection, so as to alternately realize the calibration before each light detection, or each time Calibration is performed after light detection.

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Abstract

The invention discloses a sample detection apparatus and a sample detection method. The movement of a reaction plate relative to a photoelectric detection module is controlled, an alignment detection position is calibrated before the photoelectric detection module is controlled to carry out the optical detection of the alignment detection position every time, or the photoelectric detection module is controlled to calibrate an alignment calibration position after the photoelectric detection module is controlled to carry out the optical detection of the alignment detection position every time, so the optical detection and calibration process can be realized only through controlling the reaction disc or the photoelectric detection module to move by a control sequence without changing the structure of the photoelectric detection module in order to simplify the structure of the whole apparatus and the control sequence, thereby the reliability of the apparatus is guaranteed; and calibration is carried out before or after the optical detection every time, so the drift of the photoelectric detection module can be timely compensated, and the accuracy of the optical detection every time is guaranteed.

Description

technical field [0001] The present application relates to the medical field, in particular to a sample detection device and a sample detection method. Background technique [0002] Chemiluminescence immunoassay and fluorescence immunoassay mainly realize the determination of the composition and content of the substances contained in the sample by detecting the luminescence intensity of the corresponding luminescent reaction solution of the sample to be tested. Generally, multiple reaction vessels are placed in multiple positions on the reaction plate, and the reaction plate operates under timing control, so that each reaction vessel can move among the operating positions, thereby completing light detection. Due to the particularity of the detection principle in immunoassay and the characteristics of the photoelectric detection module (such as photometer, etc.), the output of the photoelectric detection module will drift with the prolongation of use time and the change of amb...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/53
CPCG01N35/00693
Inventor 姜泽飞张震
Owner SHENZHEN MINDRAY BIO MEDICAL ELECTRONICS CO LTD