Wideleaf osbeckia root extract for preventing kidney stones, and preparation process and application thereof

A preparation process, a technology for pot grass, which is applied in the directions of medical preparations, drug combinations, plant raw materials, etc. containing active ingredients, to achieve the effects of preventing kidney stones, increasing the concentration, and reducing the content of oxalic acid and calcium

Inactive Publication Date: 2014-11-05
崔银方
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, Jasmine Grass is used for damp-heat diarrhea, gonorrhea, chronic cough, cough, hemoptysis, irregular menstruation, leucorrhea, etc. There is no literature report that Jasmine Grass or its extracts have the effect of preventing kidney stones

Method used

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  • Wideleaf osbeckia root extract for preventing kidney stones, and preparation process and application thereof
  • Wideleaf osbeckia root extract for preventing kidney stones, and preparation process and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] The preparation of embodiment 1 jar grass ethanol extract

[0016] Weigh 1.16kg of fresh young leaves of Jasmine grass, clean them, and refine them. Add 6L of ethanol solution with a volume percentage concentration of 95% to the obtained slurry, ultrasonically oscillate for 1 hour, and the frequency is 26.4kHz, and then filter at room temperature for 72 hours , the filtrate was concentrated under reduced pressure at 40°C to form a thick paste, freeze-dried, pulverized into fine powder, and passed through a 100-mesh sieve to obtain dry powder of the ethanol extract of Jasmine grass.

Embodiment 2

[0019] Example 2 Anti-calculus test research of ethanol extract of Jasmine oxalate on mouse calcium oxalate kidney stone model

[0020] ICR mice, male, weighing 28-32 g, were randomly divided into the following four groups: normal control group, model control group, test group I, and test group II, with 12 mice in each group. In addition to the normal control group, the mice were free to drink normal water every day, and the other groups were free to drink stone-forming water (containing 1% ethylene glycol + 1% ammonium chloride) for 6 consecutive weeks, and at the same time, administered the following intragastric administration Intervention: Based on the body weight, the normal control group and the model control group were intragastrically administered purified water at a dose of 0.1ml / 10g; the test group I was intragastrically administered the dry powder of Jasmine grass extract prepared in Comparative Example 1, and the test group II was intragastrically administered the p...

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Abstract

The invention discloses a wideleaf osbeckia root extract for preventing kidney stones, and a preparation process and an application thereof. The wideleaf osbeckia root extract is an ethanol extract of fresh tender leaves of a wideleaf osbeckia root; the fresh tender leaves of the wideleaf osbeckia root are extracted by an ethanol solution of which the concentration is 92-100% (v/v) after being ground; an extracting solution is concentrated into thick paste to be frozen and dried, so as to obtain the wideleaf osbeckia root extract. According to the extract disclosed by the invention, oxalic acid and calcium content in urine of a body and nephridial tissue can be obviously reduced, so as to prevent kidney stones.

Description

technical field [0001] The invention belongs to the technical field of extraction of traditional Chinese medicinal materials, and relates to an extract of jasmine grass for preventing kidney stones and its preparation process and application. Background technique [0002] Kidney calculus is a common disease of the urinary system, with an incidence rate of 3.4%-4.8%. The incidence rate increases with age, and the risk also increases. The main components of kidney stones are calcium oxalate and calcium phosphate stones, accounting for 80%-84% of all urinary tract stones, of which calcium oxalate stones account for 58.8%. Currently, extracorporeal shock wave lithotripsy (ESWL) and endourology are mainly used in the treatment of kidney stones, but it is difficult to cure kidney stones, and the postoperative recurrence rate is 78%-80%. my country has a long history in the application of traditional Chinese medicine in the treatment and prevention of recurrence of stone disease, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/185A61K36/80A61P13/04A61K127/00
Inventor 武希芬
Owner 崔银方
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