Anti-epileptic medicine composition and preparation method thereof

Abstract

The invention belongs to the technical field of medicines and preparation, in particular relates to an anti epileptic medicine composition and a preparation method thereof, the specific ratio is as follows: the weight ratio of aspirin to caffeine to phenobarbital sodium to phenytoin sodium is 1-5:1-2:1-6:3-25; the preparation method is as follows: adding medicinal starch and magnesium stearate in the mixture, stirring evenly, and processing to obtain a capsule; or adding lactose, microcrystalline cellulose, carboxymethyl cellulose formaldehyde calcium and silicic acid anhydride into the mixture for mixing evenly, and then adding carboxyl propionyl cellulose dissolved with isopropanol, mixing evenly, using a wet method for granulation, drying, finishing, and mixing with the magnesium stearate for tabletting to obtain a tablet; the anti epileptic medicine composition has the advantages of simple composition, easily obtained raw materials, simple preparation, remarkable curative effect, no toxic side effect and safety and reliability.

Description

Technical field: [0001] The invention belongs to the technical field of medicine and its preparation, and in particular relates to an antiepileptic combination medicine and a preparation method thereof, which have a good effect of treating both symptoms and root causes of epilepsy. Background technique: [0002] Epilepsy, commonly known as "shorn horn wind" or "sheep epilepsy wind", is a chronic disease that causes paroxysmal synchronous abnormal high-frequency discharges of brain neuron groups due to various reasons, resulting in transient brain dysfunction. The prevalence rate is second only to stroke; loss of consciousness during epileptic seizures can cause body falls, and limb convulsions can cause abrasions and bruises. At the same time, epileptic seizures can cause cerebral hypoxic edema and inflammation, leading to functional impairment and memory loss , lowered intelligence, repeated attacks will also bring negative psychological effects such as fear and low self-es...

AI Technical Summary

Problems solved by technology

The synchronous high-frequency discharge of neuron excitation is the electrophysiological basis of epilepsy. Animal experiments have shown that the combination of neurostimulant caffeine and inhibitor antiepileptic drugs can inhibit the synchronous discharge of neurons; modern research also believes that epileptic seizures are related to inflammation and neural habits. In addition to surgery, the clinical treatment of epilepsy in the prior art mostly adopts conservative drug treatment, and traditional western medicine mostly uses nerve inhibitors or Ca 2+ Plasma antagonists are symptomatic treatment, but in practice symptomatic treatment requires long-term medication, and most antiepileptic drugs have relatively large side effects, which can easily cause damage to the patient's systemic organs and nervous system, and the medical expenses during the treatment process are high, so a "specimen" is urgently needed. Antiepileptic drugs with less side effects

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