Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Traditional Chinese medicine compound preparation for treating migraine disease and preparation method thereof

A technology for compound preparations and migraines, which can be applied to medical formulas, nervous system diseases, medical preparations containing active ingredients, etc., and can solve problems such as expensive, impossible to eradicate permanently or completely, and toxic and side effects

Inactive Publication Date: 2015-01-07
王剑
View PDF4 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Migraine is a disease with a high incidence rate. The drugs commonly used in western medicine to treat migraine include non-steroidal anti-inflammatory analgesics to terminate headache attacks, ergotamine vasoconstrictors, and non-selective serotonin receptors. Agonists and selective 5-HT receptor agonists, antiemetics, gastric motility drugs, sedatives, etc. that relieve accompanying symptoms can control headache attacks to a certain extent, relieve symptoms, and at the same time achieve certain clinical results in preventing recurrence. curative effect, but it cannot permanently or completely eradicate the disease, and the recurrence rate is still high after taking the medicine, all of which have certain toxic and side effects to varying degrees, and are expensive

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Traditional Chinese medicine compound preparation for treating migraine disease and preparation method thereof
  • Traditional Chinese medicine compound preparation for treating migraine disease and preparation method thereof
  • Traditional Chinese medicine compound preparation for treating migraine disease and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0111] Take Angelica sinensis 25g, Chuanxiong 20g, Bupleurum 15g and add 10 times the amount of water, soak for 1 hour, steam distillation to extract the volatile oil for 6 hours, collect the volatile oil, clathrate with β-cyclodextrin to get the volatile oil clathrate, set aside; Filter, the filtrate and medicinal residues are used separately; medicinal residues are combined with 20g of gastrodia elata, 20g of silkworm, 20g of earthworm, 20g of salvia miltiorrhiza, 5g of scorpion, and 5g of centipede, adding 8 times the amount of water and decocting 3 times, each decocting for 1.5 hours, Combine the filtrates for three times, filter, and combine the filtrates obtained from Angelica, Chuanxiong and Bupleurum to extract the volatile oil, concentrate to a thick paste with a relative density of 1.30-1.35 (80°C), dry under reduced pressure, grind into fine powder, add the above-mentioned volatile oil bag Compound and appropriate amount of auxiliary materials, mixed evenly, with app...

Embodiment 2

[0113] Take 18g of Angelica sinensis, 15g of Chuanxiong, 10g of Radix Bupleurum, add 10 times the amount of water, soak for 1 hour, extract the volatile oil by steam distillation for 6 hours, collect the volatile oil, and clathrate with β-cyclodextrin to obtain a volatile oil clathrate, which is used for later use; Filter, and the filtrate and medicinal residues are used separately; the medicinal residues are combined with 15g of gastrodia elata, 15g of silkworm, 15g of earthworm, 15g of salvia miltiorrhiza, 3g of scorpion, 3g of centipede, and decocting 3 times with 8 times the amount of water, each decocting for 1.5 hours, Combine the filtrates for three times, filter, and combine the filtrates obtained from Angelica, Chuanxiong and Bupleurum to extract the volatile oil, concentrate to a thick paste with a relative density of 1.30-1.35 (80°C), dry under reduced pressure, grind into fine powder, add the above-mentioned volatile oil bag Compound and appropriate amount of auxili...

Embodiment 3

[0115] Take 10g of Angelica sinensis, 10g of Rhizoma Chuanxiong, 5g of Bupleurum bupleuri, add 10 times the amount of water, soak for 1 hour, extract the volatile oil by steam distillation for 6 hours, collect the volatile oil, and clathrate it with β-cyclodextrin to obtain a volatile oil clathrate, which is reserved; Filter, the filtrate and the dregs of the medicine are used separately; the dregs of the medicine are combined with 10g of gastrodia elata, 10g of silkworm, 10g of earthworm, 10g of salvia miltiorrhiza, 2g of scorpion, and 2g of centipede, adding 8 times the amount of water and decocting 3 times, each decocting for 1.5 hours, Combine the filtrates for three times, filter, and combine the filtrates obtained from Angelica, Chuanxiong and Bupleurum to extract the volatile oil, concentrate to a thick paste with a relative density of 1.30-1.35 (80°C), dry under reduced pressure, grind into fine powder, add the above-mentioned volatile oil bag Compound and appropriate a...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a traditional Chinese medicine compound preparation for treating a migraine disease and a preparation method thereof. The traditional Chinese medicine compound preparation is prepared by nine traditional Chinese medicines, namley angelica sinensis, ligusticum wallichii, rhizoma gastrodiae, bombyx batryticatus, earthworm, radix bupleuri, salviae miltiorrhizae, scorpion and centipede through a scientific processing technology. According to the invention, based on the theory that stasis is a pathological product of migraine, and obstruction and stagnation by blood stasis and wind-yang nuisance are pathogenesis of the migraine disease, a method for treating the blood stasis and wind syndrome migraine through activating blood and expelling wind is provided, so that the blood stasis is dissipated, and the liver wind is converged to reduce the frequency of relapse; the traditional Chinese medicine compound preparation has the characteristics that the migraine symptom can be alleviated, the relapse frequency is reduced, the duration of pain is shortened, and part of patients is healed; the traditional Chinese medicine compound preparation has good clinical treatment effects, also has the characteristics of small side effects, high convenience for carrying and taking, low price and the like, and the patient's mental and economic burden can be reduced.

Description

technical field [0001] The invention discloses a traditional Chinese medicine compound preparation for treating migraine, and also provides a preparation method of the medicine, belonging to the technical field of traditional Chinese medicine. Background technique [0002] Migraine is a disease with a high incidence rate. The drugs commonly used in western medicine to treat migraine include non-steroidal anti-inflammatory analgesics to terminate headache attacks, ergotamine vasoconstrictors, and non-selective serotonin receptors. Agonists and selective 5-HT receptor agonists, antiemetics, gastric motility drugs, sedatives, etc. that relieve accompanying symptoms can control headache attacks to a certain extent, relieve symptoms, and at the same time achieve certain clinical results in preventing recurrence. Curative effect, but can not permanently or thoroughly eradicate this disease, the relapse rate is still high after taking medicine, all have certain toxic and side effec...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K36/8988A61P25/06A61K35/56A61K35/64
CPCA61K9/1617A61K35/62A61K35/646A61K35/648A61K36/232A61K36/233A61K36/236A61K36/537A61K36/8988A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 王健
Owner 王剑
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products