Infrared spectroscopy on-line quality monitoring and controlling system applied to anaesthetic preparation

A technology of infrared spectroscopy and quality monitoring, which is used in the testing of pharmaceutical preparations, special data processing applications, instruments, etc. It can solve the problems of less than 10% transfer rate of finished products, instability, etc., and achieve fast measurement speed, non-destructiveness, and high sensitivity. Effect

Active Publication Date: 2015-01-21
INNER MONGOLIA MONGOLIAN MEDICINE CO LTD
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AI Technical Summary

Problems solved by technology

[0011] Chlorogenic acid in honeysuckle and schiaftoside in Desmodium syringae, the main medicinal ingredients in the Mongolian medicine Guri Gumu Qingre Zhike Capsules, are extremely unstable. If they are not well controlled, the transfer rate of the finished product will be less than 10%.

Method used

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specific Embodiment approach

[0027] DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS The present invention will be further described below.

[0028] Taking the application of an infrared spectrum online quality monitoring and control system in the Mongolian medicine Gurigumu Qingre Zhike Capsule as an example, the following steps are adopted:

[0029] A. In steps a and c of the preparation method of Guri Gumu Qingre Zhike Capsules, the infrared spectrum of the medicinal liquid is collected online through the collector on the multifunctional extraction tank, and samples are taken at the same time, and chlorogenic acid, chlorogenic acid, and The content of schiaftoside;

[0030] B. In the b and d steps of the preparation method of Guri Gumu Qingre Zhike Capsules, the infrared spectrum of the medicinal liquid is collected online through the collector on the concentration tank, and samples are taken at the same time, and chlorogenic acid and Schaffer are determined offline by high performance liquid chromato...

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Abstract

The invention discloses an infrared spectroscopy on-line quality monitoring and controlling system applied to anaesthetic preparations. The infrared spectroscopy on-line quality monitoring and controlling system comprises the following steps: A, a collector on a multi-functional extracting pot is used for collecting the infrared spectroscopy of a solution on line, sampling is carried out at the same time, and the content of chlorogenic acid and schaftoside is measured off line; B, a collector on a concentration pot is used for collecting the infrared spectroscopy of the solution on line, sampling is carried out at the same time, and the content of index components is measured off line; C, the infrared spectroscopy and content data obtained from the step A and the step B, of a sample is inputted into a computer to obtain the content of the index components so as to realize real-time monitoring of the index components; D, the content of the index components obtained from an on-line analysis mathematic model is inputted into a distributed control system through an OPC communication module, and an self-controlling valve field actuator in anaesthetic preparation equipment is controlled to realize the feedback control of the anaesthetic preparations in the preparing process. According to the invention, the content of the index components can be monitored in real time, and the feedback of anaesthetic composition in the preparing process can be realized.

Description

technical field [0001] The invention relates to an online quality monitoring method using infrared spectrum, in particular to the application of an infrared spectrum online quality monitoring and control system in Mongolian medicine preparations. Background technique [0002] Due to the complex composition of Mongolian medicine, it is difficult to determine its detection indicators. The production process and quality control technology of Mongolian medicine in my country is relatively low, the production equipment is backward, and there is a lack of scientific and reliable online monitoring tools, especially equipment and technical means that can quickly respond to the online quality level of products. , resulting in uneven quality of Mongolian medicine products and uneven production levels of various enterprises, which affects the clinical efficacy of medication and the development of ethnic medicines. [0003] The production process of Mongolian medicine mostly includes mu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/15G01N35/00G06F19/00
Inventor 李洪泽齐骁勇闫海涛韩风雨孔新颖
Owner INNER MONGOLIA MONGOLIAN MEDICINE CO LTD
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