Extraction method of radix astragali polysaccharide

An extraction method, technology of astragalus polysaccharides, applied in the field of extraction of astragalus polysaccharides, achieving high yield and high purity

Active Publication Date: 2015-01-28
广东康力医药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0020] The yield of astragalus polysaccharide in the above method is 16-17%, which is not high

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0048] A method for extracting astragalus polysaccharides, the method comprising the steps of:

[0049] Select sun-dried astragalus, crush it and pass through a 60-mesh sieve to get astragalus powder, add water to the astragalus powder and stir evenly, the weight ratio of astragalus powder to water is 1:7, soak in water for 10 hours, add cellulase, fiber The amount of suzyme added is 0.75%, the enzymolysis temperature is 45°C, and the pH value is 5. The above-mentioned raw materials are extracted in a microwave extraction equipment. The power of the microwave is 400-600W, the frequency is 800MHZ, and the enzymolysis is 0.1-0.5h;

[0050] Then add alkaline protease and bromelain, the addition of alkaline protease is 0.45%, the addition of bromelain is 0.4%, the enzymolysis temperature is 50 ° C, the pH value is 7.2, and the above-mentioned raw materials are placed in microwave extraction equipment for extraction. The power of the microwave is 500W, the frequency is 800MHZ, the en...

Embodiment 2

[0058] A method for extracting astragalus polysaccharides, the method comprising the steps of:

[0059] Select sun-dried astragalus, crush it and pass through a 40-mesh sieve to get astragalus powder, add water to the astragalus powder and stir evenly, the weight ratio of astragalus powder to water is 1:5, soak in water for 8 hours, add cellulase, fiber The added amount of suzyme is 0.5%, the enzymolysis temperature is 45°C, and the pH value is 5. The above-mentioned raw materials are extracted in a microwave extraction equipment. The power of the microwave is 400-600W, the frequency is 800MHZ, and the enzymolysis is 0.1h;

[0060] Then add alkaline protease and bromelain, the addition of alkaline protease is 0.2%, the addition of bromelain is 0.2%, the enzymolysis temperature is 50 ° C, the pH value is 6.8, and the above-mentioned raw materials are placed in microwave extraction equipment to extract, The power of the microwave is 400W, the frequency is 800MHZ, the enzymolysis...

Embodiment 3

[0068] A method for extracting astragalus polysaccharides, the method comprising the steps of:

[0069] Select sun-dried astragalus, crush it and pass through a 80-mesh sieve to obtain astragalus powder, add water to the astragalus powder and stir evenly, the weight ratio of astragalus powder to water is 1:10, soak in water for 16 hours, add cellulase, fiber The amount of suzyme added is 0.9%, the enzymolysis temperature is 45°C, and the pH value is 5. The above-mentioned raw materials are extracted in a microwave extraction equipment. The power of the microwave is 400-600W, the frequency is 800MHZ, and the enzymolysis is 0.1-0.5h;

[0070] Then add alkaline protease and bromelain, the addition of alkaline protease is 0.6%, the addition of bromelain is 0.5%, the enzymolysis temperature is 50 ° C, the pH value is 7.5, and the above-mentioned raw materials are placed in microwave extraction equipment for extraction. The power of the microwave is 500W, the frequency is 800MHZ, th...

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PUM

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Abstract

The invention belongs to the technical field of polysaccharide extraction, and particularly relates to an extraction method of radix astragali polysaccharides. The extraction method of radix astragali polysaccharides comprises the following steps: selecting dried radix astragali, sieving at 40-80 meshes after smashing to obtain radix astragali powder, adding water to the radix astragali powder and stirring uniformly, soaking in water for 8-16 hours, and adding active carbon for decoloration, wherein the weight proportion of the radix astragali powder to water is 1: (5-10); adding cellulose for enzymolysis; then adding alkaline protease and ficus proteinase; carrying out enzymolysis under a microwave condition; carrying out concentration and decoloration after enzymolysis; centrifuging; taking supernate for concentration and alcohol precipitation, then centrifuging, washing and precipitating by adopting ethanol, smashing after freeze drying, and thus obtaining the radix astragali polysaccharides. The polysaccharides are extracted from radix astragali by adopting the method disclosed by the invention, The action conditions of adopted enzymes are mild, fats and celluloses in the radix astragali are subjected to enzymolysis by using various different enzymes, and the polysaccharides in the radix astragali are extracted, so that the utilization rate of theradix astragali is improved; the polysaccharides obtained by using the method disclosed by the invention are not only high in yield but also high in purity.

Description

Technical field [0001] The present invention is a polysaccharide extraction technology field, which involves a method of extract of astragalus polysaccharides. Background technique [0002] The use of a large amount of antibiotics has led to a decline in human immunity, and the safe green treatment method of immunotherapy has become the goal of the world's people. Because many Chinese herbal medicines have the effect of improving autoimmunity, it is safe, efficient, low toxicChinese herbal medicine extraction is increasingly watched. [0003] Scientists are constantly discovering that polysaccharides and sugar complexes not only exist in energy sources and materials that constitute organisms, but they also exist in all cell membrane structures to participate in the life movements of various types of cells and have diverse biological functions. [0004] Astragalus has the effect of nourishing qi and solid surface, diuretic poison, pus, and sores.It is used for qi deficiency and w...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C08B37/00
Inventor 迟宗磊藏伟功丁振洋
Owner 广东康力医药有限公司
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