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Raw material composition of multi-component active wound repair material and preparation method

A raw material composition and wound repair technology, applied in medical science, bandages, absorbent pads, etc., can solve the problems of biological activity and treatment effect to be improved, and achieve the prevention of wound infection, regulation of fiber activity, anti-inflammation, and strong surface activity Effect

Inactive Publication Date: 2015-02-04
HUBEI SHUANGXING PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] In recent years, a new type of wound repair material has also appeared. Patent 200510104916.2 proposes to use silicon dioxide, sodium oxide, calcium oxide and phosphorus pentoxide to physically mix, crush, sieve (300μm), and then mix it with hyaluronic acid. Wound repair material, multi-substance mixed powder prepared by physical mixing technology, its crystal structure is still an independent single crystal mixture, and the uniformity, biological activity and therapeutic effect of the tissue need to be improved

Method used

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  • Raw material composition of multi-component active wound repair material and preparation method
  • Raw material composition of multi-component active wound repair material and preparation method

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Embodiment 1

[0017] Preparation of multi-component active wound repair materials

[0018] ⑴ Use 30-60% deionized water, 10-30% HCI solution, analyze pure ethyl orthosilicate (TE0S) 10-30%, triethyl phosphate (TEP) 6-20%, calcium nitrate (Ca(NO 3 ) 2 ·4H 2 O) 2-8%, accurately weigh deionized water, HCI solution, analyze pure ortho-ethyl silicate, triethyl phosphate, calcium nitrate, and mix evenly; (2) Place the mixture in a platinum crucible and melt at 1350℃ for 90 minutes ⑶The molten glass-like liquid is quenched in deionized water; ⑷drying; ⑸grinding, sieving and sieving to obtain powder less than 50 microns; ⑹the powder less than 50 microns and medical sodium hyaluronate Mix according to the ratio to obtain the active wound repair material gel. After testing, the multi-component active wound repair material gel has the following components in weight percentage:

[0019] SiO 2 58%

[0020] CaO 30%

[0021] P 2 O 5 6%

[0022] Medical sodium hyaluronate 6%

[00...

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Abstract

The invention discloses a raw material composition of a multi-component active wound repair material and a preparation method. The raw material composition comprises following components, by weight, 30-60% of deionized water, 10-30% of an HCl solution, 10-30% of analytically-pure tetraethoxysilane (TEOS), 6-20% of triethyl phosphate (TEP), 2-8% of calcium nitrate (Ca(NO3)2.4H2O) and 2-20% of medical sodium hyaluronate. The raw materials are prepared into external-use preparations, such as gels, ointments and the like, for treatment of skin wound repair. The multi-component active wound repair material can induce proliferation and differentiation of human epithelial cells, can promote regeneration of soft tissue, can accelerate generation of granulation tissue and can promote wound surface to heal and reduce scars, thereby having a wide medical application prospect.

Description

Technical field [0001] The invention relates to a material for treating wounds, that is, an active wound repairing material, which belongs to the technical field of medical sanitary materials and dressings. Background technique [0002] There are many dressings available in the prior art for treating wounds, but the effects of wound exudate absorption, blood vessel growth, microcirculation, wound healing, and scar reduction need to be improved, especially for diabetic ulcers, bedsores, burns and other aspects. Unexplained wounds that are difficult to heal have worse healing effects, bring greater mental and physical pain to patients, and increase the economic burden of patients. [0003] In recent years, a new type of wound repair material has also appeared. Patent 200510104916.2 proposes to use silica, sodium oxide, calcium oxide and phosphorus pentoxide to be physically mixed, crushed, sieved (300μm), and then mixed with hyaluronic acid. Wound repair materials, multi-substance m...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/28A61L15/18
Inventor 廖书辉
Owner HUBEI SHUANGXING PHARMA CO LTD
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