Oil-in-water type neomycin sulfate nosiheptide nanoemulsion antimicrobial medicine
A technology of neomycin sulfate and antibacterial drugs, applied in the field of medicine, can solve the problems of less absorption, achieve low surface tension, better antibacterial effect, and good effect
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[0032] Example Nosiheptide / g Neomycin sulfate / g Surfactant / g Co-surfactant / g Oil / g Water / g 16.17.6 28 (EL-40) 4 (ethanol) 12 (cinnamaldehyde)42.3 26.57.9 25 (EL-40) 3 (1,2-Propanediol) 14 (linoleic acid)43.6 35.56.5 28 (RH-40) 7 (Glycerol) 11 (castor oil)42 44.22.2 35 (RH-40) 5 (ethanol) 12 (Ethyl oleate)41.6 54.52.5 25 (Tween 80) 15 (glycerol) 13 (cinnamaldehyde)40 64.59.8 20 (Tween 80) 4 (Polyethylene glycol 400) 16 (soybean oil) 45.7
[0033] Preparation method: accurately weigh out nosiheptide, surfactant and co-surfactant, stir evenly at room temperature (25°C), and then slowly drip distilled water into which neomycin sulfate has been dissolved; with the amount of distilled water The viscosity of the system increases when the amount of distilled water is added to change the system from water-in-oil to oil-in-water nanoemulsion, the viscosity of the system becomes thinner from the most viscous state, and nothing is produced. Transparent neomycin sulfate and nosiheptide na...
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