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A kind of traditional Chinese medicine for treating common cold and preparation method thereof

A technology of traditional Chinese medicine and extract, applied in the field of medicine, can solve problems such as damage to the local defense function of the upper respiratory tract, invasion of latent bacteria in the upper respiratory tract, product solubility, and difficulty in reaching the standard of fritillin content.

Active Publication Date: 2015-10-28
JIANMIN GROUP YEKAITAI SINOPHARM (SUIZHOU) CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] 2. Bacteria: Bacterial infection is mostly secondary, because viral infection damages the local defense function of the upper respiratory tract, causing latent bacteria in the upper respiratory tract to take the opportunity to invade
[0009] In addition, the extraction process and specific parameters of fritillary fritillaria and comfrey yunnanensis provided in the patented preparation method of 93109013.X are not the optimal process and parameters, and the process operability of steps 1 and 3 is not feasible, and in actual production It cannot be realized, because the amount of medicinal liquid after extraction of traditional Chinese medicine is relatively large, and it is generally necessary to concentrate the medicinal liquid before it can be further made into dosage forms. In the patented process of 93109013. It is not feasible to add it in the production of granulation, and it is easy to coke after the combined extraction and direct concentration, which makes it difficult to meet the product solubility and peimin content.

Method used

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  • A kind of traditional Chinese medicine for treating common cold and preparation method thereof
  • A kind of traditional Chinese medicine for treating common cold and preparation method thereof
  • A kind of traditional Chinese medicine for treating common cold and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0067] Forsythia 416g

[0068] Raw rehmannia 430g

[0069] Dian Bupleurum 450g

[0070] Scrophulariaceae 210g

[0071] Mulberry leaves 208g

[0072] Fritillaria 208g

[0073] Banlangen 400g

[0074] Dandelion 190g

[0075] Yunnan Comfrey 220g

[0076] Bellflower 500g

[0077] Radix Seeds 416g

[0078] Licorice 218g

[0079] Take the prescription amount of Fritillaria fritillaria and Comfrey yunnanensis and grind them into coarse powder respectively, add 8 times the amount of 70% ethanol to reflux and extract twice, each time for 1.5 hours, combine the extracts, recover ethanol under reduced pressure and concentrate to a relative density of 1.32 ( 60~65℃), add a stabilizer to the extract of Fritillaria japonicus, the stabilizer is ethanol with a concentration of 75%, and the addition amount is 10% of the weight of the extract of Fritillaria japonicus, which is reserved; Wait for Shiweijing medicinal materials, decoct twice with 8 times the amount of water, 1.5 hours e...

Embodiment 2

[0086] The preparation method is the same as that of Example 1, except that the added auxiliary materials include water, and the prepared dosage form is an oral liquid.

[0087] Determination of content: according to ultraviolet spectrophotometry (Appendix VID of Chinese Pharmacopoeia 2010 edition), every 1ml of this product contains total alkaloids of fritillary fritillary and peiminin A (C 27 H45NO 3 ) shall not be less than 0.06mg.

[0088] Specifications: 10ml per bottle.

[0089] Dosage: Take orally, 2 / 3 bottle once within one year old, 1 bottle once between 1 year old and 3 years old, 2 bottles once between 4 years old and 12 years old, 3 times a day, 3 days as a course of treatment; or follow the doctor's advice.

Embodiment 3

[0091] The preparation method is the same as that of Example 1, except that the added auxiliary materials include water and sucrose, and the prepared dosage form is syrup.

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Abstract

The invention provides a traditional Chinese medicine for treating cold and a preparation method thereof. The traditional Chinese medicine is a medicament which is prepared from the following raw materials in parts by weight: 416 parts of fructus forsythia, 416 parts of dried rehmannia root, 416 parts of bupleurum candollei, 208 parts of radix scrophulariae, 208 parts of folium mori, 208 parts of thunberg fritillary bulbs, 416 parts of South Isatis Root, 208 parts of dandelion, 208 parts of onosma paniculatum, 416 parts of platycodon grandiflorum, 416 parts of semen raphani and 208 parts of liquorice. The traditional Chinese medicine provided by the invention is exact in curative effect, few in side effect and feasible in preparation method.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a traditional Chinese medicine for treating colds and a preparation method thereof. Background technique [0002] Acute upper respiratory tract infection is a common and frequently-occurring disease in children. It can occur all year round, and each person can suffer from it several times a year. Pathogens mainly invade the nose, pharynx, tonsils and larynx and cause inflammation. If the inflammation is limited to a certain part, it is named according to the inflammation of the part, such as acute rhinitis, acute tonsillitis, etc., otherwise it is collectively referred to as upper respiratory tract infection. [0003] 1. Viruses: account for about 90% of acute upper respiratory infections. Common viruses include: ①myxoviruses include influenza virus (type A and type B), parainfluenza virus (type 1, 2, 3, 4), respiratory syncytial Viruses, etc.; ②Adenovirus: There are current...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8966A61P11/00
CPCA61K9/1652A61K36/195A61K36/233A61K36/288A61K36/30A61K36/31A61K36/34A61K36/484A61K36/605A61K36/634A61K36/804A61K36/808A61K36/8966A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 任平远佘金燕孟晓波杨殊燕朱龙玲布忠江聂一鑫
Owner JIANMIN GROUP YEKAITAI SINOPHARM (SUIZHOU) CO LTD
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