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Application of traditional Chinese medicine composition to preparation of drug for treating allergic conjunctivitis

A technology of allergic conjunctivitis and composition, which is applied in the direction of drug combination, drug delivery, medical raw materials derived from ferns/filamentous plants, etc., can solve the problems of long treatment course and large side effects, and achieve good curative effect and effective High efficiency, no toxic side effects

Inactive Publication Date: 2015-04-08
GUANGDONG JUZHICHENG TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, the commonly used ocular anti-allergic drugs mainly include mast cell stabilizers, antihistamines, and glucocorticoids, but these drugs have a long course of treatment and relatively large side effects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment l

[0048] Take 20kg of honeysuckle, 20kg of cassia seeds, 10kg of plantain seeds, 10kg of skullcap, 10kg of Scutellaria baicalensis, 5kg of mint, 5kg of equisetum, 10kg of licorice, add water 10 times the total weight of the medicinal materials, soak for 60 minutes, decoct 3 times, each time 3 hours, filter, combine the filtrates, concentrate the filtrate under reduced pressure to extract with a relative density of 1.05-1.25, add ethanol to the alcohol content of 70% (v / v), let stand for 24 hours, take the supernatant, and recover the ethanol , concentrated, dried, and prepared into capsules by adding conventional auxiliary materials, each capsule containing crude drug 0.6g.

Embodiment 2

[0050] Take 18kg of honeysuckle, 18kg of cassia seeds, 18kg of plantain seeds, 16kg of scutellaria baicalensis, 10kg of Scutellaria baicalensis, 6 kg of mint, 6 kg of equisetum, 20 kg of licorice, add 12 times the total weight of the medicinal materials in water, soak 45 kg and decocted 3 times , filtered for 2 hours each time, combined the filtrates, concentrated the filtrate under reduced pressure to an extract with a relative density of 1.05-1.25, added ethanol to the alcohol content of 70% (v / v), stood for 24 hours, took the supernatant , recovering ethanol, concentrating, drying, adding conventional excipients and compressing to obtain tablets, each containing 0.5g of crude drug.

Embodiment 3

[0052]Take honeysuckle 3kg, cassia seed 3kg, psyllium 18kg, scutellaria baicalensis 12kg, Qianliguang 16kg, mint 6kg, equisetum 8kg, licorice 22kg, add 8 of the total weight of the medicinal materials, soak 30, decoct 3 times for 2 hours each time , filter, combine the filtrates, concentrate the filtrate under reduced pressure to extract with relative density of 1.05-1.25, add ethanol to the alcohol content of 80% (v / v), let stand for 24 hours, take the supernatant, recover ethanol, concentrate , dry, add conventional excipients to prepare granules, pack in bags, each bag contains 2.5g crude drug.

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PUM

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Abstract

The invention discloses application of a traditional Chinese medicine composition to preparation of a drug for treating allergic conjunctivitis, relating to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from Chinese herbal medicines such as honeysuckle, semen cassiae, semen plantaginis, scutellaria baicalensis, mint, equisetum hyemale, climbing groundsel herbs and liquorice. The traditional Chinese medicine composition disclosed by the invention is high in effect taking speed, short in treatment course and high in cure rate and can be popularized and applied on the aspect of treating allergic conjunctivitis. The traditional Chinese medicine composition disclosed by the invention can take a synergistic effect and simultaneously take the effects of dispelling wind and evils, clearing away heat and toxic materials as well as dispelling wind and arresting itching.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to the use of a traditional Chinese medicine composition in preparing medicine for treating allergic conjunctivitis. Background technique [0002] Allergic conjunctivitis, also known as allergic conjunctivitis, is a hypersensitivity reaction of the conjunctiva to external allergens. It mainly includes type I allergy and type IV allergy, among which allergic conjunctivitis caused by type I allergy is the most common. Allergic conjunctivitis caused by type Ⅰ allergy is immediate, mainly referring to allergic conjunctivitis including seasonal allergic conjunctivitis, perennial allergic conjunctivitis, giant papillary conjunctivitis, vernal keratoconjunctivitis, atopic Keratoconjunctivitis, etc.; allergic conjunctivitis caused by type Ⅳ allergy was delayed, mainly bullous conjunctivitis. [0003] Clinical symptoms: eye itching, which can occur in almost all pati...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/68A61P27/02A61P27/14
CPCA61K36/355A61K9/0053A61K9/08A61K9/16A61K9/20A61K9/48A61K36/11A61K36/28A61K36/482A61K36/484A61K36/534A61K36/539A61K36/68A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 邓凤桂
Owner GUANGDONG JUZHICHENG TECH
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