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New strain of Lactobacillus crispatus

A technology of Lactobacillus crispatus and strains, applied to Lactobacillus, bacteria, bacteria and other directions used in food preparation, can solve problems such as the inability to use glycogen fermentable carbon and the like

Active Publication Date: 2018-01-23
S P M D SA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0020] Furthermore, many of these strains are unable to use glycogen as a source of fermentable carbon (Martín R. et al., 2008)

Method used

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  • New strain of Lactobacillus crispatus
  • New strain of Lactobacillus crispatus
  • New strain of Lactobacillus crispatus

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Embodiment Construction

[0038] The present invention relates to a new isolated Lactobacillus crispatus strain designated IP174178 and deposited at CNCM under accession number 1-4646, and any isolated Lactobacillus crispatus strain having the same characteristics as this isolated strain.

[0039] The term "Lactobacilli" refers to all Lactobacillus bacteria, Gram-positive bacteria (immobile, variable shape and size), and facultative anaerobes. Most lactobacilli convert lactose and other simple sugars into lactic acid. They are found in the vagina and gastrointestinal tract, and they constitute an important component of the intestinal and vaginal flora.

[0040] Lactobacillus crispatus is one of the dominant species of vaginal flora in Europe, the United States and Japan (Antonio, MAD et al., 1999).

[0041] The isolated strain Lactobacillus crispatus IP174178 has the following functional properties:

[0042] - Higher H 2 o 2 and lactic acid production (more than 7g / L);

[0043] - the ability to gr...

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Abstract

The present invention relates to an isolated Lactobacillus crispatus strain designated IP174178 and deposited at CNCM under number 1-464 or an isolated strain having the same characteristics as IP174178. The present invention also relates to pharmaceutical or nutraceutical compositions comprising such strains, and their use for the treatment or prevention of genital infections.

Description

field of invention [0001] The present invention relates to novel specific strains of Lactobacillus crispatus isolated from samples of healthy tissue and any strains having the same characteristics and compositions comprising the same. [0002] In healthy women, the urogenital microbiota contains almost 50 different microbial species. Among these microorganisms, 95% of the population consisted of various strains of Lactobacillus (including "Dedelainia ( bacillus)”). These lactobacilli contribute to protection against pathogens through a variety of mechanisms, including the production of hydrogen peroxide, lactic acid and bacteriocins, which inhibit the adhesion and spread of pathogens. In particular, these lactobacilli Glycogen present in vaginal mucus generates lactic acid to maintain acidic pH. Therefore, various pathogens of vaginal flora, such as Gardnerella vaginalis (Gardnerella vaginalis), two road Prevotella (Prevotella bivia), gonorrhea The growth of Neisseriagonorr...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C12N1/20A61K35/747A61P31/10A61P31/04A61P13/02A61P15/02A23L33/00C12R1/225
CPCA61F13/2074A61K35/747C12R2001/225C12N1/205C12N1/20A61P13/02A61P15/02A61P31/04A61P31/10A23L33/135A61K9/0036A23V2002/00A23V2200/3204A23V2400/11
Inventor A.尼沃利兹
Owner S P M D SA