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New application of burnet tannin and astragalus polysaccharide

A technology of Astragalus polysaccharide and Burnet tannin, which is applied in the new application field of Burnet tannin and Astragalus polysaccharide to achieve the effect of improving drug efficacy and activity

Active Publication Date: 2017-09-15
广西英路维特药物有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] At present, there is no report on the compatibility of the active ingredients in Burnet and the active ingredients in Astragalus

Method used

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  • New application of burnet tannin and astragalus polysaccharide
  • New application of burnet tannin and astragalus polysaccharide
  • New application of burnet tannin and astragalus polysaccharide

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Example 1 tablet

[0028]

[0029] [Preparation method] Take the prescription amount of astragalus polysaccharide and Burnet tannin, add auxiliary materials and mix well, pass through 80 mesh sieve, then add 95% ethanol to make soft material, granulate with 16 mesh mesh; Add 50g of magnesium stearate, mix well, press into 1000 tablets, and coat to obtain.

Embodiment 2

[0030] Example 2 Capsules

[0031]

[0032] [Preparation method] Take the prescription amount of astragalus polysaccharide and Burnet tannin, add auxiliary materials and mix well, pass through 80 mesh sieve, then add 95% ethanol to make soft material, granulate with 16 mesh mesh; Capsules, made of 1000 capsules in total.

Embodiment 3

[0033] Embodiment 3 soft capsules

[0034]

[0035] [Preparation method] Take the prescription amount of astragalus polysaccharide and Burnet tannin, dry at 60°C, mix well, crush into subdivisions, add soybean oil and mix well, and make 1000 soft capsules.

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PUM

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Abstract

The present invention provides the use of Burnetia tannin in preparing a medicine for treating or / or preventing bone marrow suppression in combination with astragalus polysaccharide. After combined use of Burnetia tannin and astragalus polysaccharide, the invention exerts a synergistic effect, and its pharmacodynamic activity is significantly improved, thereby providing a new choice for clinical medication.

Description

technical field [0001] The invention provides new applications of burnet tannins and astragalus polysaccharides. Background technique [0002] Myelosuppression is the most common and important complication of cancer radiotherapy and chemotherapy. The significant decrease of peripheral blood leukocytes and platelets can lead to fatal infection and hemorrhage, which seriously limits the progress and prognosis of tumor treatment. Worldwide, treatment-related mortality associated with severe myelosuppression ranges from 4% to 12%. Most of the reasons are due to severe myelosuppression and agranulocytosis caused by various uncontrollable infections. In addition, fever and hemorrhage during the myelosuppressive stage make the patient need to be hospitalized for systematic anti-infection treatment, hemostasis, blood transfusion, etc., which indirectly increases the treatment cost of cancer patients and deteriorates the quality of life of patients. Therefore, bone marrow suppress...

Claims

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Application Information

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IPC IPC(8): A61K31/715A61K36/739A61P7/00A61K31/7024A61K36/481
Inventor 苏柘僮熊永爱张帅杰
Owner 广西英路维特药物有限公司
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